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Sodium bicarbonate versus isotonic saline solution to prevent contrast-induced nephropathy: a systematic review and meta-analysis / Lina Maria Serna Higuita ; John Fredy Nieto Ríos ; Jorge Hernando Donado Gómez
Título : Sodium bicarbonate versus isotonic saline solution to prevent contrast-induced nephropathy: a systematic review and meta-analysis Otros títulos : El bicarbonato de sodio en comparación con solución salina isotónica para prevenir la nefropatía inducida por contraste: Una revisión sistemática y meta-análisis Tipo de documento : documento electrónico Autores : Lina Maria Serna Higuita, ; John Fredy Nieto Ríos, ; Jorge Hernando Donado Gómez, Fecha de publicación : 2015 Títulos uniformes : Colombia Médica Idioma : Inglés (eng) Palabras clave : Contrast induced nephropathy acute kidney injury sodium bicarbonate sodium chloride Resumen : Introduction: Contrast-induced nephropathy is one of the main causes of acute kidney injury and increased hospital-acquired morbidity and mortality. The use of sodium bicarbonate for nephroprotection has emerged as a preventative strategy; however, its efficacy is controversial compared to other strategies, such as hydration using 0.9% saline solution. Objective: To compare the effectiveness of sodium bicarbonate vs. hydration using 0.9% saline solution to prevent contrast-induced acute kidney injury. Methods: A systematic review of studies registered in the COCHRANE, PUBMED, MEDLINE, LILACS, SCIELO and EMBASE databases was conducted. Randomized controlled studies that evaluated the use of 0.9% saline solution vs. sodium bicarbonate to prevent contrast-induced nephropathy were included. Results: A total of 22 studies (5,686 patients) were included. Sodium bicarbonate did not decrease the risk of contrast-induced nephropathy (RD= 0.00; 95% CI= -0.02 to 0.03; p= 0.83; I2= 0%). No significant differences were found in the demand for renal replacement therapy (RD= 0.00; 95% CI= -0.01 to 0-01; I2 = 0%; p= 0.99) or in mortality (RD= -0.00; 95% CI= -0.001 to 0.001; I2 = 0%; p= 0.51). Conclusions: Sodium bicarbonate administration is not superior to the use of 0.9% saline solution for preventing contrast-induced nephropathy in patients with risk factors, nor is it better at reducing mortality or the need for renal replacement therapy. Mención de responsabilidad : Carlos Andres Zapata-Chica, Diana Bello Marquez, Lina Maria Serna-Higuita, John Fredy Nieto-Ríos, Fabian David Casas-Arroyave, Jorge Hernando Donado-Gómez Referencia : Colomb Med (Cali). 2015 Sep 30;46(3):90-103. DOI (Digital Object Identifier) : 10.25100/cm.v46i3.1925 PMID : 26600623 Derechos de uso : CC BY En línea : https://colombiamedica.univalle.edu.co/index.php/comedica/article/view/1925 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3913 Sodium bicarbonate versus isotonic saline solution to prevent contrast-induced nephropathy: a systematic review and meta-analysis = El bicarbonato de sodio en comparación con solución salina isotónica para prevenir la nefropatía inducida por contraste: Una revisión sistemática y meta-análisis [documento electrónico] / Lina Maria Serna Higuita, ; John Fredy Nieto Ríos, ; Jorge Hernando Donado Gómez, . - 2015.
Obra : Colombia Médica
Idioma : Inglés (eng)
Palabras clave : Contrast induced nephropathy acute kidney injury sodium bicarbonate sodium chloride Resumen : Introduction: Contrast-induced nephropathy is one of the main causes of acute kidney injury and increased hospital-acquired morbidity and mortality. The use of sodium bicarbonate for nephroprotection has emerged as a preventative strategy; however, its efficacy is controversial compared to other strategies, such as hydration using 0.9% saline solution. Objective: To compare the effectiveness of sodium bicarbonate vs. hydration using 0.9% saline solution to prevent contrast-induced acute kidney injury. Methods: A systematic review of studies registered in the COCHRANE, PUBMED, MEDLINE, LILACS, SCIELO and EMBASE databases was conducted. Randomized controlled studies that evaluated the use of 0.9% saline solution vs. sodium bicarbonate to prevent contrast-induced nephropathy were included. Results: A total of 22 studies (5,686 patients) were included. Sodium bicarbonate did not decrease the risk of contrast-induced nephropathy (RD= 0.00; 95% CI= -0.02 to 0.03; p= 0.83; I2= 0%). No significant differences were found in the demand for renal replacement therapy (RD= 0.00; 95% CI= -0.01 to 0-01; I2 = 0%; p= 0.99) or in mortality (RD= -0.00; 95% CI= -0.001 to 0.001; I2 = 0%; p= 0.51). Conclusions: Sodium bicarbonate administration is not superior to the use of 0.9% saline solution for preventing contrast-induced nephropathy in patients with risk factors, nor is it better at reducing mortality or the need for renal replacement therapy. Mención de responsabilidad : Carlos Andres Zapata-Chica, Diana Bello Marquez, Lina Maria Serna-Higuita, John Fredy Nieto-Ríos, Fabian David Casas-Arroyave, Jorge Hernando Donado-Gómez Referencia : Colomb Med (Cali). 2015 Sep 30;46(3):90-103. DOI (Digital Object Identifier) : 10.25100/cm.v46i3.1925 PMID : 26600623 Derechos de uso : CC BY En línea : https://colombiamedica.univalle.edu.co/index.php/comedica/article/view/1925 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3913 Reserva
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