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Update of hepatitis C in Colombia / Juan Ignacio Marín Zuluaga ; Octavio Germán Muñoz Maya ; Juan Carlos Restrepo Gutiérrez ; Óscar Mauricio Santos Sánchez
Título : Update of hepatitis C in Colombia Tipo de documento : documento electrónico Autores : Juan Ignacio Marín Zuluaga, ; Octavio Germán Muñoz Maya, ; Juan Carlos Restrepo Gutiérrez, ; Óscar Mauricio Santos Sánchez, Fecha de publicación : 2018 Títulos uniformes : Current Tropical Medicine Reports Dimensiones : Idioma : Inglés (eng) Palabras clave : Hepatitis C HCV Colombia South America Direct-acting antiviral DAA Resumen : Purpose of Review The goal is to describe the epidemiology, disease burden and detection, available therapies, and current challenges to access care for people with chronic hepatitis C infection in Colombia. Recent Findings There are no detailed statistics about the prevalence of HCVin Colombia; nonetheless, majority of patients with hepatitis C are infected with genotype 1 and having received blood products before 1996 represents the main risk factor. The use of intravenous drugs has started to be recognized as a population at risk that is in increment. Direct-acting antivirals became available in 2016 in Colombia thanks to a centralized purchase program with the Pan American Health Organization. Summary There are well-established guidelines for the use of available antivirals for all disease stages and genotypes and sustained virologic response (SVR) rates are 95 to 100%. Underdiagnosis, access and linkage to care, and disease stigmatization have contributed to a low number of patients that have actually completed their therapy. Mención de responsabilidad : Federico Hinestrosa, Juan Ignacio Marín, Octavio Muñoz Maya, Oscar Santos & Juan Carlos Restrepo Referencia : Curr Trop Med Rep (2018) 5: 133 DOI (Digital Object Identifier) : 10.1007/s40475-018-0147-5 En línea : https://link.springer.com/article/10.1007/s40475-018-0147-5 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3423 Update of hepatitis C in Colombia [documento electrónico] / Juan Ignacio Marín Zuluaga, ; Octavio Germán Muñoz Maya, ; Juan Carlos Restrepo Gutiérrez, ; Óscar Mauricio Santos Sánchez, . - 2018 . - ; PDF.
Obra : Current Tropical Medicine Reports
Idioma : Inglés (eng)
Palabras clave : Hepatitis C HCV Colombia South America Direct-acting antiviral DAA Resumen : Purpose of Review The goal is to describe the epidemiology, disease burden and detection, available therapies, and current challenges to access care for people with chronic hepatitis C infection in Colombia. Recent Findings There are no detailed statistics about the prevalence of HCVin Colombia; nonetheless, majority of patients with hepatitis C are infected with genotype 1 and having received blood products before 1996 represents the main risk factor. The use of intravenous drugs has started to be recognized as a population at risk that is in increment. Direct-acting antivirals became available in 2016 in Colombia thanks to a centralized purchase program with the Pan American Health Organization. Summary There are well-established guidelines for the use of available antivirals for all disease stages and genotypes and sustained virologic response (SVR) rates are 95 to 100%. Underdiagnosis, access and linkage to care, and disease stigmatization have contributed to a low number of patients that have actually completed their therapy. Mención de responsabilidad : Federico Hinestrosa, Juan Ignacio Marín, Octavio Muñoz Maya, Oscar Santos & Juan Carlos Restrepo Referencia : Curr Trop Med Rep (2018) 5: 133 DOI (Digital Object Identifier) : 10.1007/s40475-018-0147-5 En línea : https://link.springer.com/article/10.1007/s40475-018-0147-5 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3423 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000757 AC-2018-044 Archivo digital Producción Científica Artículos científicos Disponible Hepatitis C virus seroprevalence in multi-transfused patients in Colombia / Sergio Jaramillo Velásquez ; Jorge Hernando Donado Gómez ; Ángela Patricia Estrada Naranjo ; Sandra Yepes
Título : Hepatitis C virus seroprevalence in multi-transfused patients in Colombia Tipo de documento : documento electrónico Autores : Sergio Jaramillo Velásquez, ; Jorge Hernando Donado Gómez, ; Ángela Patricia Estrada Naranjo, ; Sandra Yepes, Fecha de publicación : 2005 Títulos uniformes : Journal of Clinical Virology Idioma : Inglés (eng) Palabras clave : HCV prevalence multi-transfused patients Colombia Resumen : Background: Hepatitis C Vtrus (HCV) refection is a public health problem worldwide, with particular relevance m multi-transfused patients given that HCV is principally transmitted by exposure to infected blood Study design: Between February and September 2003 a cross-sectional study was carried out m four hospital centres m Bogotfi and Medellln, Colombia, to determine the risk factors for HCV refection m 500 multi-transfused patients. Results: The study population was distributed in five groups haemophlha, haemodyahsls, acute bleeding, oncologlcal illnesses and sickle cell disease or thalassemla Serum samples from patients were tested for HCV aXltlbodles (Asxym TM, Abbott) An overall prevalence (9 0%, 95% confidence interval (CI) 6 4 11 6) (45/500) of HCV infection was found Antl-HCV aXltlbodles were detected m 32 2% of patients with haemophlha, 6 1% of patients undergoing haemodlalysls, 7 1% of patients with sickle cell disease or thalassemla, 2 6% of patients with acute bleeding and 3 4% of patients with oncologlcal or hematological diseases The mare risk t; actors associated with refection by HCV were to be hemophdlc (odds ratio, OR 18 03, 95% CI 3 96 114 17), having received transfusions before 1995 (OR 12 27, 95% CI 5 57 27 69), and having received more than 48 units of blood components (OR 6 08, 95% CI 3 06 12 1) In the multlwxlate axmlysls, only the year of transfusions (before 1995) remained significantly associated with risk of infection by HCV. Conclusions: The data show a 3-fold reduction m the refection risk between 1993 and 1995, when the serological screening for HCV in blood donors was being introduced A reduction greater than 90% was achteved by 1995 when the screening coverage reached 99% Mención de responsabilidad : Mauricio Beltrân, Maria-Cristina Navas, Fernando De la Hoz, Maria Mercedes Muñoz, Sergio Jaramillo, Cecilia Estrada, Lucia Del Pilar Cortés, Maria Patricia Arbelâez, Jorge Donado, Gloria Barco, Martha Luna, Gustavo Adolfo Uribe, Amalia de Maldonado, Juan Carlos Restrepo, Gonzalo Correa, Paula Borda, Gloria Rey, Marlen de Neira, Angela Estrada, Sandra Yepes, Oscar Beltrân, Javier Pacheco, Iván Villegas, Jorge Boshell Referencia : J Clin Virol. 2005 Dec;34Suppl,2:S33-8. DOI (Digital Object Identifier) : 10.1016/S1386-6532(05)80032-0 PMID : 16461238 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1386653205800320 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3438 Hepatitis C virus seroprevalence in multi-transfused patients in Colombia [documento electrónico] / Sergio Jaramillo Velásquez, ; Jorge Hernando Donado Gómez, ; Ángela Patricia Estrada Naranjo, ; Sandra Yepes, . - 2005.
Obra : Journal of Clinical Virology
Idioma : Inglés (eng)
Palabras clave : HCV prevalence multi-transfused patients Colombia Resumen : Background: Hepatitis C Vtrus (HCV) refection is a public health problem worldwide, with particular relevance m multi-transfused patients given that HCV is principally transmitted by exposure to infected blood Study design: Between February and September 2003 a cross-sectional study was carried out m four hospital centres m Bogotfi and Medellln, Colombia, to determine the risk factors for HCV refection m 500 multi-transfused patients. Results: The study population was distributed in five groups haemophlha, haemodyahsls, acute bleeding, oncologlcal illnesses and sickle cell disease or thalassemla Serum samples from patients were tested for HCV aXltlbodles (Asxym TM, Abbott) An overall prevalence (9 0%, 95% confidence interval (CI) 6 4 11 6) (45/500) of HCV infection was found Antl-HCV aXltlbodles were detected m 32 2% of patients with haemophlha, 6 1% of patients undergoing haemodlalysls, 7 1% of patients with sickle cell disease or thalassemla, 2 6% of patients with acute bleeding and 3 4% of patients with oncologlcal or hematological diseases The mare risk t; actors associated with refection by HCV were to be hemophdlc (odds ratio, OR 18 03, 95% CI 3 96 114 17), having received transfusions before 1995 (OR 12 27, 95% CI 5 57 27 69), and having received more than 48 units of blood components (OR 6 08, 95% CI 3 06 12 1) In the multlwxlate axmlysls, only the year of transfusions (before 1995) remained significantly associated with risk of infection by HCV. Conclusions: The data show a 3-fold reduction m the refection risk between 1993 and 1995, when the serological screening for HCV in blood donors was being introduced A reduction greater than 90% was achteved by 1995 when the screening coverage reached 99% Mención de responsabilidad : Mauricio Beltrân, Maria-Cristina Navas, Fernando De la Hoz, Maria Mercedes Muñoz, Sergio Jaramillo, Cecilia Estrada, Lucia Del Pilar Cortés, Maria Patricia Arbelâez, Jorge Donado, Gloria Barco, Martha Luna, Gustavo Adolfo Uribe, Amalia de Maldonado, Juan Carlos Restrepo, Gonzalo Correa, Paula Borda, Gloria Rey, Marlen de Neira, Angela Estrada, Sandra Yepes, Oscar Beltrân, Javier Pacheco, Iván Villegas, Jorge Boshell Referencia : J Clin Virol. 2005 Dec;34Suppl,2:S33-8. DOI (Digital Object Identifier) : 10.1016/S1386-6532(05)80032-0 PMID : 16461238 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1386653205800320 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3438 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000005 AC-2005-004 Archivo digital Producción Científica Artículos científicos Disponible