Inicio
Resultado de la búsqueda
6 búsqueda de la palabra clave 'Paracoccidioidomycosis'
Clasificado(s) por (Año de edición descendente) Refinar búsqueda Genera el flujo rss de la búsqueda
Enlace permanente de la investigaciónSystemic paracoccidioidomycosis in a patient with enzymatic myeloperoxidase deficiency and acute lymphoblastic leukemia: case report / Luis Eduardo Buitrago Naranjo
Título : Systemic paracoccidioidomycosis in a patient with enzymatic myeloperoxidase deficiency and acute lymphoblastic leukemia: case report Tipo de documento : documento electrónico Autores : Luis Eduardo Buitrago Naranjo, Fecha de publicación : 2022 Títulos uniformes : Bulletin of the National Research Center Idioma : Inglés (eng) Palabras clave : Acute lymphoblastic leukemia lymphoblastic Case report Enzymatic deficiency Myeloperoxidase deficiency Paracoccidioidomycosis Resumen : Background: Paracoccidioidomycosis is a systemic fungal infection that is potentially fatal, and the most prevalent of its kind in Latin America. The predisposition to infection appears to be related to abnormalities in cellular immunity, given its low prevalence in endemic regions. The role of myeloperoxidase deficiency has not been elucidated. Case presentation: We present a case of 48-year-old female patient with acute lymphoblastic leukemia, stem cell transplant candidate, who developed a fever with lymphadenopathy and lung nodules, consistent with paracoccidioidomycosis infection, in whom a myeloperoxidase deficiency was later discovered. The treatment of the hematologic malignancy had a good impact solving the enzymatic deficiency and antifungal therapy achieve controlling the infection. Conclusions: This case lays out the possible association between acute leukemia, an alteration in neutrophil function (needed to fight fungal infections) and an infection due to Paracoccidioides brasiliensis. Mención de responsabilidad : Sebastián Hoyos, Cristián Camilo Agudelo, Diana Mercedes Lozano & Luis Eduardo Buitrago Referencia : Bull Natl Res Cent. 2022;46(1):286. DOI (Digital Object Identifier) : 10.1186/s42269-022-00973-z PMID : 36593896 Derechos de uso : CC BY En línea : https://bnrc.springeropen.com/articles/10.1186/s42269-022-00973-z Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6110 Systemic paracoccidioidomycosis in a patient with enzymatic myeloperoxidase deficiency and acute lymphoblastic leukemia: case report [documento electrónico] / Luis Eduardo Buitrago Naranjo, . - 2022.
Obra : Bulletin of the National Research Center
Idioma : Inglés (eng)
Palabras clave : Acute lymphoblastic leukemia lymphoblastic Case report Enzymatic deficiency Myeloperoxidase deficiency Paracoccidioidomycosis Resumen : Background: Paracoccidioidomycosis is a systemic fungal infection that is potentially fatal, and the most prevalent of its kind in Latin America. The predisposition to infection appears to be related to abnormalities in cellular immunity, given its low prevalence in endemic regions. The role of myeloperoxidase deficiency has not been elucidated. Case presentation: We present a case of 48-year-old female patient with acute lymphoblastic leukemia, stem cell transplant candidate, who developed a fever with lymphadenopathy and lung nodules, consistent with paracoccidioidomycosis infection, in whom a myeloperoxidase deficiency was later discovered. The treatment of the hematologic malignancy had a good impact solving the enzymatic deficiency and antifungal therapy achieve controlling the infection. Conclusions: This case lays out the possible association between acute leukemia, an alteration in neutrophil function (needed to fight fungal infections) and an infection due to Paracoccidioides brasiliensis. Mención de responsabilidad : Sebastián Hoyos, Cristián Camilo Agudelo, Diana Mercedes Lozano & Luis Eduardo Buitrago Referencia : Bull Natl Res Cent. 2022;46(1):286. DOI (Digital Object Identifier) : 10.1186/s42269-022-00973-z PMID : 36593896 Derechos de uso : CC BY En línea : https://bnrc.springeropen.com/articles/10.1186/s42269-022-00973-z Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6110 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001970 AC-2022-122 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
AC-2022-122Adobe Acrobat PDF
Título : Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiency Tipo de documento : documento electrónico Autores : Carlos Andrés Agudelo, ; Johnayro Gutiérrez Restrepo, ; Alejandro Vélez Hoyos, Fecha de publicación : 2009 Títulos uniformes : Revista do Instituto de Medicina Tropical de São Paulo Idioma : Inglés (eng) Palabras clave : Paracoccidioidomycosis adrenal insufficiency cortisol Resumen : The authors report two cases of adrenal insufficiency secondary to infiltration of the adrenal glands by Paracoccidioides brasiliensis. The first patient had been treated for a chronic multifocal form of paracoccidiodomycosis 11 years ago. The diagnosis of the mycosis was done simultaneous with that of the adrenal insufficiency in the second patient. In both patients the diagnosis was done by direct visualization of fungus in adrenal biopsies. They were treated with hormonal supplements and itraconazol by 12 and six months, without relapses during the follow-up perio Mención de responsabilidad : Carlos Andrés Agudelo, Carolina Muñoz, Alex Ramírez, Jonhairo Gutierrez, Santiago Velez, Juan Camilo Perez, Alejandro Velez, Angela María Tobon, Angela Restrepo Referencia : Rev Inst Med Trop Sao Paulo. 2009 Jan-Feb;51(1):45-8. DOI (Digital Object Identifier) : 10.1590/s0036-46652009000100008 PMID : 19229390 Derechos de uso : CC BY-NC En línea : http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652009000100008&l [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3490 Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiency [documento electrónico] / Carlos Andrés Agudelo, ; Johnayro Gutiérrez Restrepo, ; Alejandro Vélez Hoyos, . - 2009.
Obra : Revista do Instituto de Medicina Tropical de São Paulo
Idioma : Inglés (eng)
Palabras clave : Paracoccidioidomycosis adrenal insufficiency cortisol Resumen : The authors report two cases of adrenal insufficiency secondary to infiltration of the adrenal glands by Paracoccidioides brasiliensis. The first patient had been treated for a chronic multifocal form of paracoccidiodomycosis 11 years ago. The diagnosis of the mycosis was done simultaneous with that of the adrenal insufficiency in the second patient. In both patients the diagnosis was done by direct visualization of fungus in adrenal biopsies. They were treated with hormonal supplements and itraconazol by 12 and six months, without relapses during the follow-up perio Mención de responsabilidad : Carlos Andrés Agudelo, Carolina Muñoz, Alex Ramírez, Jonhairo Gutierrez, Santiago Velez, Juan Camilo Perez, Alejandro Velez, Angela María Tobon, Angela Restrepo Referencia : Rev Inst Med Trop Sao Paulo. 2009 Jan-Feb;51(1):45-8. DOI (Digital Object Identifier) : 10.1590/s0036-46652009000100008 PMID : 19229390 Derechos de uso : CC BY-NC En línea : http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652009000100008&l [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3490 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000058 AC-2009-020 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2009-020.pdfAdobe Acrobat PDF
Título : Pulmonary paracoccidioidomycosis Tipo de documento : documento electrónico Autores : Carlos Andrés Agudelo, Fecha de publicación : 2008 Títulos uniformes : Seminars in Respiratory and Critical Care Medicine Idioma : Inglés (eng) Palabras clave : Paracoccidioidomycosis Paracoccidioides brasiliensis clinical presentations diagnosis immunopathology treatment Resumen : Paracoccidioidomycosis (formerly known as South American blastomycosis) is produced by the thermally dimorphic fungus Paracoccidioides brasiliensis. Most often this mycosis runs a chronic progressive course affecting preferentially the lungs followed by the skin, mucous membranes, adrenals, and reticuloendothelial organs. Acute-subacute presentations can be observed in children and immunosuppressed patients. Occasionally, self-limited infections have been documented. Two types of clinical presentations are described, the acute-subacute (juvenile) and the chronic (adult) forms of the disease. Paracoccidioidomycosis predominates in adult males (13:1); this gender difference is not observed in children or adolescents. The mycosis is limited geographically to various Latin American countries, with the greatest number of cases originating in Brazil, The fungus's natural habitat has not been precisely defined, although it is supposed to be a soil-inhabiting microorganism. No outbreaks have been reported. P. brasiliensis is capable of entering into prolonged periods of latency as is demonstrated by its diagnosis in patients who have moved outside the recognized endemic areas. This review updates clinicians and laboratory workers on the characteristics of a mycosis seldom reported outside of the Latin American countries. Mención de responsabilidad : Angela Restrepo, Gil Benard, Cláudio C. de Castro, Carlos A. Agudelo, Angela M. Tobón Referencia : Semin Respir Crit Care Med. 2008 Apr;29(2):182-97. DOI (Digital Object Identifier) : 10.1055/s-2008-1063857 PMID : 18366000 En línea : https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-2008-1063857 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4441 Pulmonary paracoccidioidomycosis [documento electrónico] / Carlos Andrés Agudelo, . - 2008.
Obra : Seminars in Respiratory and Critical Care Medicine
Idioma : Inglés (eng)
Palabras clave : Paracoccidioidomycosis Paracoccidioides brasiliensis clinical presentations diagnosis immunopathology treatment Resumen : Paracoccidioidomycosis (formerly known as South American blastomycosis) is produced by the thermally dimorphic fungus Paracoccidioides brasiliensis. Most often this mycosis runs a chronic progressive course affecting preferentially the lungs followed by the skin, mucous membranes, adrenals, and reticuloendothelial organs. Acute-subacute presentations can be observed in children and immunosuppressed patients. Occasionally, self-limited infections have been documented. Two types of clinical presentations are described, the acute-subacute (juvenile) and the chronic (adult) forms of the disease. Paracoccidioidomycosis predominates in adult males (13:1); this gender difference is not observed in children or adolescents. The mycosis is limited geographically to various Latin American countries, with the greatest number of cases originating in Brazil, The fungus's natural habitat has not been precisely defined, although it is supposed to be a soil-inhabiting microorganism. No outbreaks have been reported. P. brasiliensis is capable of entering into prolonged periods of latency as is demonstrated by its diagnosis in patients who have moved outside the recognized endemic areas. This review updates clinicians and laboratory workers on the characteristics of a mycosis seldom reported outside of the Latin American countries. Mención de responsabilidad : Angela Restrepo, Gil Benard, Cláudio C. de Castro, Carlos A. Agudelo, Angela M. Tobón Referencia : Semin Respir Crit Care Med. 2008 Apr;29(2):182-97. DOI (Digital Object Identifier) : 10.1055/s-2008-1063857 PMID : 18366000 En línea : https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-2008-1063857 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4441 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000941 AC-2008-028 Archivo digital Producción Científica Artículos científicos Disponible
Título : Activity of two different triazoles in a murine model of paracoccidioidomycosis Tipo de documento : documento electrónico Autores : Susana Restrepo, ; Ángela María Tabares Velásquez, ; Ángela Restrepo Moreno, Fecha de publicación : 1992 Títulos uniformes : Revista do Instituto de Medicina Tropical de São Paulo Idioma : Inglés (eng) Palabras clave : Paracoccidioidomycosis Experimental Treatment Triazole Itraconazol Schering 39304 Resumen : A new orally absorbable triazole (Schering 39304) with a long serum half-life in man (60 hours), was tried in a murine model of progressive paracoccidioidomycosis and compared with itraconazole, another triazole which has proven effective in this mycosis. Only 15% of the infected, untreated mice survived while 53 to 75% of the animals receiving itraconazole survived. Mice treated with Schering 39304 exhibited higher (86 - 100%) survival rates. Statistically, the 5 mg/kg Sch 39304 was superior to the 50 mg/kg itraconazole dose. Lung cultures showed that 20 mg/kg/day of Sch achieved sterilization of the infectious foci. These results indicate that the new triazole will have a place in the treatment of paracoccidioidomycosis. Mención de responsabilidad : Susana Restrepo; Angela M. Tabares; Angela Restrepo Referencia : Rev Inst Med Trop Sao Paulo. 1992 Mar-Apr;34(2):171-6. DOI (Digital Object Identifier) : 10.1590/s0036-46651992000200014 PMID : 1340032 Derechos de uso : CC BY-NC En línea : http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651992000200014 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4364 Activity of two different triazoles in a murine model of paracoccidioidomycosis [documento electrónico] / Susana Restrepo, ; Ángela María Tabares Velásquez, ; Ángela Restrepo Moreno, . - 1992.
Obra : Revista do Instituto de Medicina Tropical de São Paulo
Idioma : Inglés (eng)
Palabras clave : Paracoccidioidomycosis Experimental Treatment Triazole Itraconazol Schering 39304 Resumen : A new orally absorbable triazole (Schering 39304) with a long serum half-life in man (60 hours), was tried in a murine model of progressive paracoccidioidomycosis and compared with itraconazole, another triazole which has proven effective in this mycosis. Only 15% of the infected, untreated mice survived while 53 to 75% of the animals receiving itraconazole survived. Mice treated with Schering 39304 exhibited higher (86 - 100%) survival rates. Statistically, the 5 mg/kg Sch 39304 was superior to the 50 mg/kg itraconazole dose. Lung cultures showed that 20 mg/kg/day of Sch achieved sterilization of the infectious foci. These results indicate that the new triazole will have a place in the treatment of paracoccidioidomycosis. Mención de responsabilidad : Susana Restrepo; Angela M. Tabares; Angela Restrepo Referencia : Rev Inst Med Trop Sao Paulo. 1992 Mar-Apr;34(2):171-6. DOI (Digital Object Identifier) : 10.1590/s0036-46651992000200014 PMID : 1340032 Derechos de uso : CC BY-NC En línea : http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651992000200014 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4364 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000864 AC-1992-003 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
1992-003.pdfAdobe Acrobat PDF
Título : Electron microscopic study of conidia produced by the mycelium of Paracoccidioides brasiliensis Tipo de documento : documento electrónico Autores : Maria E. Salazar, ; Luz Elena Cano Restrepo, ; Ángela Restrepo Moreno, Fecha de publicación : 1991 Títulos uniformes : Mycopathologia Idioma : Inglés (eng) Palabras clave : Paracoccidioidomycosis mycelium conidia ultrastructure Resumen : The ultrastructure of asexual spores (conidia) produced by the mycelial form of Paracoccidioides brasiliensis was studied for the first time with transmission electron microscopy, using thin sections of aldehyde-osmium-fixed and epoxy-resin-embedded samples. The various types of conidia observed in the sections correlated well with previous light-microscopic descriptions. These types were intercalary or apical conidia, depending on their location along the originating hyphae. As in previous studies they were characterized as arthroconidia, aleuriospores and sessile or pedunculate pyriform conidia. The sporogenous cells were clearly distinguished from hyphal cells by the thickness and appearance of their cell walls. Copious fibrillar material (glycocalyx) detected at the cell surface was stained with ruthenium red during the fixation process. Typical subcellular organelles (nucleus, nucleolus, mitochondria, ribosomes, etc) were found in most of the sections. It was concluded that the spores produced by the mycelial phase of P. brasiliensis possess all attributes of viable and physiologically competent eukaryotic cells. Mención de responsabilidad : Mercedes R. Edwards, M. E. Salazar, W. A. Samsonoff, L. E. Cano, G. A. Ostrander & A. Restrepo Referencia : Mycopathologia. 1991 Jun;114(3):169-77. DOI (Digital Object Identifier) : 10.1007/BF00437210 PMID : 1886643 En línea : https://link.springer.com/article/10.1007/BF00437210 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4360 Electron microscopic study of conidia produced by the mycelium of Paracoccidioides brasiliensis [documento electrónico] / Maria E. Salazar, ; Luz Elena Cano Restrepo, ; Ángela Restrepo Moreno, . - 1991.
Obra : Mycopathologia
Idioma : Inglés (eng)
Palabras clave : Paracoccidioidomycosis mycelium conidia ultrastructure Resumen : The ultrastructure of asexual spores (conidia) produced by the mycelial form of Paracoccidioides brasiliensis was studied for the first time with transmission electron microscopy, using thin sections of aldehyde-osmium-fixed and epoxy-resin-embedded samples. The various types of conidia observed in the sections correlated well with previous light-microscopic descriptions. These types were intercalary or apical conidia, depending on their location along the originating hyphae. As in previous studies they were characterized as arthroconidia, aleuriospores and sessile or pedunculate pyriform conidia. The sporogenous cells were clearly distinguished from hyphal cells by the thickness and appearance of their cell walls. Copious fibrillar material (glycocalyx) detected at the cell surface was stained with ruthenium red during the fixation process. Typical subcellular organelles (nucleus, nucleolus, mitochondria, ribosomes, etc) were found in most of the sections. It was concluded that the spores produced by the mycelial phase of P. brasiliensis possess all attributes of viable and physiologically competent eukaryotic cells. Mención de responsabilidad : Mercedes R. Edwards, M. E. Salazar, W. A. Samsonoff, L. E. Cano, G. A. Ostrander & A. Restrepo Referencia : Mycopathologia. 1991 Jun;114(3):169-77. DOI (Digital Object Identifier) : 10.1007/BF00437210 PMID : 1886643 En línea : https://link.springer.com/article/10.1007/BF00437210 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4360 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000860 AC-1991-002 Archivo digital Producción Científica Artículos científicos Disponible Permalink
