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Reproducibility of a protocol for standardized reading of chest X-rays of children household contact of patients with tuberculosis / Lina Marcela Cadavid Álvarez ; Lucila Beatriz Molinares Arevalo    

Público ISBD Título : Reproducibility of a protocol for standardized reading of chest X-rays of children household contact of patients with tuberculosis Tipo de documento : documento electrónico Autores : Lina Marcela Cadavid Álvarez, ; Lucila Beatriz Molinares Arevalo, Fecha de publicación : 2022 Títulos uniformes : BMC Pediatrics Idioma : Inglés (eng) Palabras clave : Tuberculosis  Pulmonary  Latent Tuberculosis  Clinical Protocols  Radiography  Thoracic  Observer Variation  Reproducibility of Results Resumen : Background: The interpretation of the chest radiograph may vary because it depends on the reader and due to the non-specificity of findings in tuberculosis (TB). We aim to assess the reproducibility of a standardized chest radiograph reading protocol in contacts of patients with pulmonary TB under the 5 years of age. Methods: Descriptive, cross-sectional study with children under the age of five, household contacts of patients with confirmed pulmonary TB from Medellín, Bello and Itagüí (Colombia) between Jan-01-2015 and May-31-2016. Standardized reading protocol: two radiologists, blinded independent reading, use of template (Dr. Andronikou design) in case of disagreement a third reading was performed. Kappa coefficient for intra and inter observer agreement, and prevalence ratio were estimated of sociodemographic characteristics, TB exposure and interpretation of chest X-ray. Results: From 278 children, standardized reading found 255 (91.7%) normal X-rays, 10 (3.6%) consistent with TB, and 13 (4.7%) other alterations. Global agreement was 91.3% (Kappa = 0.51). Inter-observer agreement between readers 1-2 was 90.0% (Kappa = 0.59) and 1-3 93.2% (Kappa = 0.59). Intra-observer agreement for reader 1 was 95.5% (Kappa = 0.86), 2 84.0% (Kappa = 0.51), and 3 94.7% (Kappa = 0.68). Greater inter-observer disagreement was between readers 1-2 for soft tissue density suggestive of adenopathy (4.6%), airspace opacification (1.17%) and pleural effusion (0.58%); between readers 1-3 for soft tissue density suggestive of adenopathy (4.2%), opacification of airspace (2.5%) and cavities (0.8%). Conclusions: Chest radiographs are an affordable tool that contributes to the diagnosis of TB, so having a standardized reading protocol showed good agreement and improves the reproducibility of radiograph interpretation. Mención de responsabilidad : María Margarita Lozano-Acosta, María Alejandra Rubiano-Arenas, Lina Marcela Cadavid, Guillermo Vélez-Parra, Beatriz Molinares, Diana Marcela Marín-Pineda, María Patricia Arbeláez-Montoya & Dione Benjumea-Bedoya Referencia : BMC Pediatr. 2022 May 24;22(1):307. DOI (Digital Object Identifier) : 10.1186/s12887-022-03347-6 PMID : 35610599 Derechos de uso : CC BY En línea : https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-022-03347-6 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6082 Reproducibility of a protocol for standardized reading of chest X-rays of children household contact of patients with tuberculosis [documento electrónico] / Lina Marcela Cadavid Álvarez, ; Lucila Beatriz Molinares Arevalo,  . - 2022. Obra : BMC Pediatrics Idioma : Inglés (eng) Palabras clave : Tuberculosis  Pulmonary  Latent Tuberculosis  Clinical Protocols  Radiography  Thoracic  Observer Variation  Reproducibility of Results Resumen : Background: The interpretation of the chest radiograph may vary because it depends on the reader and due to the non-specificity of findings in tuberculosis (TB). We aim to assess the reproducibility of a standardized chest radiograph reading protocol in contacts of patients with pulmonary TB under the 5 years of age. Methods: Descriptive, cross-sectional study with children under the age of five, household contacts of patients with confirmed pulmonary TB from Medellín, Bello and Itagüí (Colombia) between Jan-01-2015 and May-31-2016. Standardized reading protocol: two radiologists, blinded independent reading, use of template (Dr. Andronikou design) in case of disagreement a third reading was performed. Kappa coefficient for intra and inter observer agreement, and prevalence ratio were estimated of sociodemographic characteristics, TB exposure and interpretation of chest X-ray. Results: From 278 children, standardized reading found 255 (91.7%) normal X-rays, 10 (3.6%) consistent with TB, and 13 (4.7%) other alterations. Global agreement was 91.3% (Kappa = 0.51). Inter-observer agreement between readers 1-2 was 90.0% (Kappa = 0.59) and 1-3 93.2% (Kappa = 0.59). Intra-observer agreement for reader 1 was 95.5% (Kappa = 0.86), 2 84.0% (Kappa = 0.51), and 3 94.7% (Kappa = 0.68). Greater inter-observer disagreement was between readers 1-2 for soft tissue density suggestive of adenopathy (4.6%), airspace opacification (1.17%) and pleural effusion (0.58%); between readers 1-3 for soft tissue density suggestive of adenopathy (4.2%), opacification of airspace (2.5%) and cavities (0.8%). Conclusions: Chest radiographs are an affordable tool that contributes to the diagnosis of TB, so having a standardized reading protocol showed good agreement and improves the reproducibility of radiograph interpretation. Mención de responsabilidad : María Margarita Lozano-Acosta, María Alejandra Rubiano-Arenas, Lina Marcela Cadavid, Guillermo Vélez-Parra, Beatriz Molinares, Diana Marcela Marín-Pineda, María Patricia Arbeláez-Montoya & Dione Benjumea-Bedoya Referencia : BMC Pediatr. 2022 May 24;22(1):307. DOI (Digital Object Identifier) : 10.1186/s12887-022-03347-6 PMID : 35610599 Derechos de uso : CC BY En línea : https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-022-03347-6 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6082

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Pulmonary imaging in coronavirus disease 2019 (COVID-19): a series of 140 Latin American children / Lina Marcela Cadavid Álvarez  

Público ISBD Título : Pulmonary imaging in coronavirus disease 2019 (COVID-19): a series of 140 Latin American children Tipo de documento : documento electrónico Autores : Lina Marcela Cadavid Álvarez, Fecha de publicación : 2021 Títulos uniformes : Pediatric Radiology Idioma : Inglés (eng) Palabras clave : Chest  Children  Computed tomography  Coronavirus disease 2019  Lungs  Pulmonary  Radiography  Severe acute respiratory syndrome coronavirus 2 Resumen : Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which resulted in the worldwide coronavirus disease 2019 (COVID-19) pandemic of 2020, has particularly affected Latin America. Objective: The purpose of the study was to analyze the imaging findings of pulmonary COVID-19 in a large pediatric series. Materials and methods: Children with SARS-CoV-2 infection confirmed by either quantitative reverse transcription-polymerase chain reaction from nasopharyngeal swabs or presence of circulating immunoglobulin M (IgM) antibodies and who underwent chest radiograph or CT or both were included in this retrospective multicenter study. Three pediatric radiologists independently reviewed radiographs and CTs to identify the presence, localization, distribution and extension of pulmonary lesions. Results: We included 140 children (71 female; median age 6.3 years, interquartile range 1.6–12.1 years) in the study. Peribronchial thickening (93%), ground-glass opacities (79%) and vascular engorgement (63%) were the most frequent findings on 131 radiographs. Ground-glass opacities (91%), vascular engorgement (84%) and peribronchial thickening (72%) were the most frequent findings on 32 CTs. Peribronchial thickening (100%), ground-glass opacities (83%) and pulmonary vascular engorgement (79%) were common radiograph findings in asymptomatic children (n=25). Ground-glass opacity and consolidation were significantly higher in children who needed intensive care admission or died (92% and 48%), in contrast with children with a favorable outcome (71% and 24%, respectively; P Mención de responsabilidad : Carlos F. Ugas-Charcape, María Elena Ucar, Judith Almanza-Aranda, Emiliana Rizo-Patrón, Claudia Lazarte-Rantes, Pablo Caro-Domínguez, Lina Cadavid, Lizbet Pérez-Marrero, Tatiana Fazecas, Lucía Gomez, Mariana Sánchez Curiel, Walter Pacheco, Ana Rizzi, Andrés García-Bayce, Efigenia Bendeck, Mario Montaño, Pedro Daltro & José D. Arce-V Referencia : Pediatr Radiol. 2021 Aug;51(9):1597-1607. DOI (Digital Object Identifier) : 10.1007/s00247-021-05055-2 PMID : 33791841 En línea : https://link.springer.com/article/10.1007%2Fs00247-021-05055-2 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5856 Pulmonary imaging in coronavirus disease 2019 (COVID-19): a series of 140 Latin American children [documento electrónico] / Lina Marcela Cadavid Álvarez,  . - 2021. Obra : Pediatric Radiology Idioma : Inglés (eng) Palabras clave : Chest  Children  Computed tomography  Coronavirus disease 2019  Lungs  Pulmonary  Radiography  Severe acute respiratory syndrome coronavirus 2 Resumen : Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which resulted in the worldwide coronavirus disease 2019 (COVID-19) pandemic of 2020, has particularly affected Latin America. Objective: The purpose of the study was to analyze the imaging findings of pulmonary COVID-19 in a large pediatric series. Materials and methods: Children with SARS-CoV-2 infection confirmed by either quantitative reverse transcription-polymerase chain reaction from nasopharyngeal swabs or presence of circulating immunoglobulin M (IgM) antibodies and who underwent chest radiograph or CT or both were included in this retrospective multicenter study. Three pediatric radiologists independently reviewed radiographs and CTs to identify the presence, localization, distribution and extension of pulmonary lesions. Results: We included 140 children (71 female; median age 6.3 years, interquartile range 1.6–12.1 years) in the study. Peribronchial thickening (93%), ground-glass opacities (79%) and vascular engorgement (63%) were the most frequent findings on 131 radiographs. Ground-glass opacities (91%), vascular engorgement (84%) and peribronchial thickening (72%) were the most frequent findings on 32 CTs. Peribronchial thickening (100%), ground-glass opacities (83%) and pulmonary vascular engorgement (79%) were common radiograph findings in asymptomatic children (n=25). Ground-glass opacity and consolidation were significantly higher in children who needed intensive care admission or died (92% and 48%), in contrast with children with a favorable outcome (71% and 24%, respectively; P Mención de responsabilidad : Carlos F. Ugas-Charcape, María Elena Ucar, Judith Almanza-Aranda, Emiliana Rizo-Patrón, Claudia Lazarte-Rantes, Pablo Caro-Domínguez, Lina Cadavid, Lizbet Pérez-Marrero, Tatiana Fazecas, Lucía Gomez, Mariana Sánchez Curiel, Walter Pacheco, Ana Rizzi, Andrés García-Bayce, Efigenia Bendeck, Mario Montaño, Pedro Daltro & José D. Arce-V Referencia : Pediatr Radiol. 2021 Aug;51(9):1597-1607. DOI (Digital Object Identifier) : 10.1007/s00247-021-05055-2 PMID : 33791841 En línea : https://link.springer.com/article/10.1007%2Fs00247-021-05055-2 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5856

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Diagnostic performance of CT esophagography in patients with suspected esophageal rupture / Álvaro Enrique Sanabria Quiroga  

Público ISBD Título : Diagnostic performance of CT esophagography in patients with suspected esophageal rupture Tipo de documento : documento electrónico Autores : Álvaro Enrique Sanabria Quiroga, Fecha de publicación : 2014 Títulos uniformes : Emergency Radiology Idioma : Inglés (eng) Palabras clave : Esophageal perforation  multidetector computed tomography  diagnosis  radiography  esophagogram Resumen : Esophageal rupture is a surgical catastrophe. The gold standard for diagnosing is iodine, water-soluble contrast medium esophagography. CT esophagography has shown promising results. This study aimed to assess the diagnostic performance of CT esophagography in patients with a suspicion of esophageal rupture. This prospective study assessed the performance of a diagnostic test and was approved by local IRB committee. Patients who presented with a clinical suspicion of esophageal rupture were included. CT esophagography findings were described by the emergency radiologist. Clinical outcomes (presence or absence of esophageal rupture) were reported by surgeons. The operative characteristics were calculated. A final predictive scale for rupture was built. A total of 64 patients were recruited (age 26.5 years, 90 % male, 82 % trauma). Sensitivity, specificity, and positive and negative likelihood ratios (LRs) were 77.7 % (95 % confidence interval (CI) 45–100), 94.3 % (87.2–100), 14 (9.81–19.9), and 0.24 (0.05–1.22), respectively. The final model for predicting rupture included five variables: age (odds ratio (OR) 1.03; 95 % CI, 0.95–1.11; p = 0.04), leakage of contrast media into the mediastinum or pleural space (OR 10.0; 95 % CI, 0.64–156.9; p = 0.10), extraluminal air or fluid collections (OR 43.1; 95 % CI, 1.52–1217.3; p = 0.027), esophageal wall thickening (OR 10.1; 95 % CI, 0.50–202.8; p = 0.12), and left pneumothorax or pleural effusion (OR 6.5; 95 % CI, 0.31–132.7; p = 0.2). The overall agreement was 0.40 (95 % CI, 0.09–0.72) for the predictive model. The model sensitivity was 50.0 %, and the specificity was 98.4 %. CT esophagography shows a good diagnostic performance in patients with a suspected esophageal rupture Mención de responsabilidad : Tatiana Suarez-Poveda, Carlos H Morales-Uribe, Alvaro Sanabria, Adriana Llano-Sánchez, Andrés Mauricio Valencia-Delgado, Luis Fernando Rivera-Velázquez, John Fernando Bedoya-Ospina Referencia : Emerg Radiol. 2014 Oct;21(5):505-10. DOI (Digital Object Identifier) : 10.1007/s10140-014-1222-4 PMID : 24748526 En línea : https://link.springer.com/article/10.1007%2Fs10140-014-1222-4 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3784 Diagnostic performance of CT esophagography in patients with suspected esophageal rupture [documento electrónico] / Álvaro Enrique Sanabria Quiroga,  . - 2014. Obra : Emergency Radiology Idioma : Inglés (eng) Palabras clave : Esophageal perforation  multidetector computed tomography  diagnosis  radiography  esophagogram Resumen : Esophageal rupture is a surgical catastrophe. The gold standard for diagnosing is iodine, water-soluble contrast medium esophagography. CT esophagography has shown promising results. This study aimed to assess the diagnostic performance of CT esophagography in patients with a suspicion of esophageal rupture. This prospective study assessed the performance of a diagnostic test and was approved by local IRB committee. Patients who presented with a clinical suspicion of esophageal rupture were included. CT esophagography findings were described by the emergency radiologist. Clinical outcomes (presence or absence of esophageal rupture) were reported by surgeons. The operative characteristics were calculated. A final predictive scale for rupture was built. A total of 64 patients were recruited (age 26.5 years, 90 % male, 82 % trauma). Sensitivity, specificity, and positive and negative likelihood ratios (LRs) were 77.7 % (95 % confidence interval (CI) 45–100), 94.3 % (87.2–100), 14 (9.81–19.9), and 0.24 (0.05–1.22), respectively. The final model for predicting rupture included five variables: age (odds ratio (OR) 1.03; 95 % CI, 0.95–1.11; p = 0.04), leakage of contrast media into the mediastinum or pleural space (OR 10.0; 95 % CI, 0.64–156.9; p = 0.10), extraluminal air or fluid collections (OR 43.1; 95 % CI, 1.52–1217.3; p = 0.027), esophageal wall thickening (OR 10.1; 95 % CI, 0.50–202.8; p = 0.12), and left pneumothorax or pleural effusion (OR 6.5; 95 % CI, 0.31–132.7; p = 0.2). The overall agreement was 0.40 (95 % CI, 0.09–0.72) for the predictive model. The model sensitivity was 50.0 %, and the specificity was 98.4 %. CT esophagography shows a good diagnostic performance in patients with a suspected esophageal rupture Mención de responsabilidad : Tatiana Suarez-Poveda, Carlos H Morales-Uribe, Alvaro Sanabria, Adriana Llano-Sánchez, Andrés Mauricio Valencia-Delgado, Luis Fernando Rivera-Velázquez, John Fernando Bedoya-Ospina Referencia : Emerg Radiol. 2014 Oct;21(5):505-10. DOI (Digital Object Identifier) : 10.1007/s10140-014-1222-4 PMID : 24748526 En línea : https://link.springer.com/article/10.1007%2Fs10140-014-1222-4 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3784

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