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Reproducibility of a protocol for standardized reading of chest X-rays of children household contact of patients with tuberculosis / Lina Marcela Cadavid Álvarez ; Lucila Beatriz Molinares Arevalo
Título : Reproducibility of a protocol for standardized reading of chest X-rays of children household contact of patients with tuberculosis Tipo de documento : documento electrónico Autores : Lina Marcela Cadavid Álvarez, ; Lucila Beatriz Molinares Arevalo, Fecha de publicación : 2022 Títulos uniformes : BMC Pediatrics Idioma : Inglés (eng) Palabras clave : Tuberculosis Pulmonary Latent Tuberculosis Clinical Protocols Radiography Thoracic Observer Variation Reproducibility of Results Resumen : Background: The interpretation of the chest radiograph may vary because it depends on the reader and due to the non-specificity of findings in tuberculosis (TB). We aim to assess the reproducibility of a standardized chest radiograph reading protocol in contacts of patients with pulmonary TB under the 5 years of age. Methods: Descriptive, cross-sectional study with children under the age of five, household contacts of patients with confirmed pulmonary TB from Medellín, Bello and Itagüí (Colombia) between Jan-01-2015 and May-31-2016. Standardized reading protocol: two radiologists, blinded independent reading, use of template (Dr. Andronikou design) in case of disagreement a third reading was performed. Kappa coefficient for intra and inter observer agreement, and prevalence ratio were estimated of sociodemographic characteristics, TB exposure and interpretation of chest X-ray. Results: From 278 children, standardized reading found 255 (91.7%) normal X-rays, 10 (3.6%) consistent with TB, and 13 (4.7%) other alterations. Global agreement was 91.3% (Kappa = 0.51). Inter-observer agreement between readers 1-2 was 90.0% (Kappa = 0.59) and 1-3 93.2% (Kappa = 0.59). Intra-observer agreement for reader 1 was 95.5% (Kappa = 0.86), 2 84.0% (Kappa = 0.51), and 3 94.7% (Kappa = 0.68). Greater inter-observer disagreement was between readers 1-2 for soft tissue density suggestive of adenopathy (4.6%), airspace opacification (1.17%) and pleural effusion (0.58%); between readers 1-3 for soft tissue density suggestive of adenopathy (4.2%), opacification of airspace (2.5%) and cavities (0.8%). Conclusions: Chest radiographs are an affordable tool that contributes to the diagnosis of TB, so having a standardized reading protocol showed good agreement and improves the reproducibility of radiograph interpretation. Mención de responsabilidad : María Margarita Lozano-Acosta, María Alejandra Rubiano-Arenas, Lina Marcela Cadavid, Guillermo Vélez-Parra, Beatriz Molinares, Diana Marcela Marín-Pineda, María Patricia Arbeláez-Montoya & Dione Benjumea-Bedoya Referencia : BMC Pediatr. 2022 May 24;22(1):307. DOI (Digital Object Identifier) : 10.1186/s12887-022-03347-6 PMID : 35610599 Derechos de uso : CC BY En línea : https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-022-03347-6 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6082 Reproducibility of a protocol for standardized reading of chest X-rays of children household contact of patients with tuberculosis [documento electrónico] / Lina Marcela Cadavid Álvarez, ; Lucila Beatriz Molinares Arevalo, . - 2022.
Obra : BMC Pediatrics
Idioma : Inglés (eng)
Palabras clave : Tuberculosis Pulmonary Latent Tuberculosis Clinical Protocols Radiography Thoracic Observer Variation Reproducibility of Results Resumen : Background: The interpretation of the chest radiograph may vary because it depends on the reader and due to the non-specificity of findings in tuberculosis (TB). We aim to assess the reproducibility of a standardized chest radiograph reading protocol in contacts of patients with pulmonary TB under the 5 years of age. Methods: Descriptive, cross-sectional study with children under the age of five, household contacts of patients with confirmed pulmonary TB from Medellín, Bello and Itagüí (Colombia) between Jan-01-2015 and May-31-2016. Standardized reading protocol: two radiologists, blinded independent reading, use of template (Dr. Andronikou design) in case of disagreement a third reading was performed. Kappa coefficient for intra and inter observer agreement, and prevalence ratio were estimated of sociodemographic characteristics, TB exposure and interpretation of chest X-ray. Results: From 278 children, standardized reading found 255 (91.7%) normal X-rays, 10 (3.6%) consistent with TB, and 13 (4.7%) other alterations. Global agreement was 91.3% (Kappa = 0.51). Inter-observer agreement between readers 1-2 was 90.0% (Kappa = 0.59) and 1-3 93.2% (Kappa = 0.59). Intra-observer agreement for reader 1 was 95.5% (Kappa = 0.86), 2 84.0% (Kappa = 0.51), and 3 94.7% (Kappa = 0.68). Greater inter-observer disagreement was between readers 1-2 for soft tissue density suggestive of adenopathy (4.6%), airspace opacification (1.17%) and pleural effusion (0.58%); between readers 1-3 for soft tissue density suggestive of adenopathy (4.2%), opacification of airspace (2.5%) and cavities (0.8%). Conclusions: Chest radiographs are an affordable tool that contributes to the diagnosis of TB, so having a standardized reading protocol showed good agreement and improves the reproducibility of radiograph interpretation. Mención de responsabilidad : María Margarita Lozano-Acosta, María Alejandra Rubiano-Arenas, Lina Marcela Cadavid, Guillermo Vélez-Parra, Beatriz Molinares, Diana Marcela Marín-Pineda, María Patricia Arbeláez-Montoya & Dione Benjumea-Bedoya Referencia : BMC Pediatr. 2022 May 24;22(1):307. DOI (Digital Object Identifier) : 10.1186/s12887-022-03347-6 PMID : 35610599 Derechos de uso : CC BY En línea : https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-022-03347-6 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6082 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001929 AC-2022-090 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
AC-2022-090Adobe Acrobat PDF Systematic review of the literature on reproducibility of the interpretation of renal biopsy in lupus nephritis / Mauricio Restrepo Escobar ; Paula Andrea Granda Carvajal ; Fabián Alberto Jaimes Barragán
Título : Systematic review of the literature on reproducibility of the interpretation of renal biopsy in lupus nephritis Tipo de documento : documento electrónico Autores : Mauricio Restrepo Escobar, ; Paula Andrea Granda Carvajal, ; Fabián Alberto Jaimes Barragán, Fecha de publicación : 2017 Títulos uniformes : Lupus Idioma : Inglés (eng) Palabras clave : Biopsy nephritis reliability renal lupus reproducibility of results systematic review Resumen : Objective: Before using a test, it should be determined whether the results are reliable. The reliability of the interpretation of renal biopsy in patients with lupus nephritis has not been clearly elucidated. Our objective was to estimate inter and intraobserver reliability of the histological classification, as well as activity and chronicity indices in renal biopsy of patients with lupus nephritis. Methods: We conducted a systematic search of the literature, which included articles in any language, using PubMed, Embase, Cochrane and Lilacs databases. Search terms included were: reproducibility, reliability, agreement, systemic lupus erythematosus and lupus nephritis. Comparative studies with any design were included, regardless of the year or the language of publication. Two investigators, independently, screened the literature published in accordance with pre-established inclusion and exclusion criteria. Results: We found 13 relevant studies. Inter-observer reproducibility of most measurements was moderate or low, despite the fact that, in most cases, the readings were made by expert nephropathologists. There was great diversity among designs, participants, including samples and outcomes evaluated in different studies. Although there are too many reports on the clinical use, studies evaluating the reliability of classifications on renal biopsy in lupus nephritis are rare. The quality of the methodological design and reporting was fair. Conclusion: The interpretation of renal biopsy in lupus nephritis is poorly reproducible, causing serious doubts about its validity and its clinical application. As it can lead to serious diagnosis, treatment and prognosis errors, it is necessary to intensify research in this field. Mención de responsabilidad : M Restrepo-Escobar, P A Granda-Carvajal, F Jaimes Referencia : Lupus. 2017 Dec;26(14):1502-1512. DOI (Digital Object Identifier) : 10.1177/0961203317706556 PMID : 28441914 En línea : https://journals.sagepub.com/doi/abs/10.1177/0961203317706556 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4048 Systematic review of the literature on reproducibility of the interpretation of renal biopsy in lupus nephritis [documento electrónico] / Mauricio Restrepo Escobar, ; Paula Andrea Granda Carvajal, ; Fabián Alberto Jaimes Barragán, . - 2017.
Obra : Lupus
Idioma : Inglés (eng)
Palabras clave : Biopsy nephritis reliability renal lupus reproducibility of results systematic review Resumen : Objective: Before using a test, it should be determined whether the results are reliable. The reliability of the interpretation of renal biopsy in patients with lupus nephritis has not been clearly elucidated. Our objective was to estimate inter and intraobserver reliability of the histological classification, as well as activity and chronicity indices in renal biopsy of patients with lupus nephritis. Methods: We conducted a systematic search of the literature, which included articles in any language, using PubMed, Embase, Cochrane and Lilacs databases. Search terms included were: reproducibility, reliability, agreement, systemic lupus erythematosus and lupus nephritis. Comparative studies with any design were included, regardless of the year or the language of publication. Two investigators, independently, screened the literature published in accordance with pre-established inclusion and exclusion criteria. Results: We found 13 relevant studies. Inter-observer reproducibility of most measurements was moderate or low, despite the fact that, in most cases, the readings were made by expert nephropathologists. There was great diversity among designs, participants, including samples and outcomes evaluated in different studies. Although there are too many reports on the clinical use, studies evaluating the reliability of classifications on renal biopsy in lupus nephritis are rare. The quality of the methodological design and reporting was fair. Conclusion: The interpretation of renal biopsy in lupus nephritis is poorly reproducible, causing serious doubts about its validity and its clinical application. As it can lead to serious diagnosis, treatment and prognosis errors, it is necessary to intensify research in this field. Mención de responsabilidad : M Restrepo-Escobar, P A Granda-Carvajal, F Jaimes Referencia : Lupus. 2017 Dec;26(14):1502-1512. DOI (Digital Object Identifier) : 10.1177/0961203317706556 PMID : 28441914 En línea : https://journals.sagepub.com/doi/abs/10.1177/0961203317706556 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4048 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000648 AC-2017-037 Archivo digital Producción Científica Artículos científicos Disponible