Inicio
Resultado de la búsqueda
1 búsqueda de la palabra clave 'Staphylococcal Infections'
Clasificado(s) por (Año de edición descendente) Refinar búsqueda Genera el flujo rss de la búsqueda
Enlace permanente de la investigación
Validation of VIRSTA and Predicting Risk of Endocarditis Using a Clinical Tool (PREDICT) Scores to Determine the Priority of Echocardiography in Patients With Staphylococcus aureus Bacteremia / Juan Sebastián Peinado Acevedo
Accompagne Reply to Karakonstantis, et al; Zervou and Zacharioudakis; and Rasmussen, et al / Juan Sebastián Peinado Acevedo
Título : Validation of VIRSTA and Predicting Risk of Endocarditis Using a Clinical Tool (PREDICT) Scores to Determine the Priority of Echocardiography in Patients With Staphylococcus aureus Bacteremia Tipo de documento : documento electrónico Autores : Juan Sebastián Peinado Acevedo, Fecha de publicación : 2021 Títulos uniformes : Clinical Infectious Diseases Idioma : Inglés (eng) Palabras clave : Bacteremia Echocardiography Endocarditis Staphylococcal Infections Staphylococcus aureus Resumen : Introduction: Infective endocarditis (IE) secondary to Staphylococcus aureus bacteremia (SAB) has high morbidity and mortality. The systematic use of echocardiography in SAB is controversial. We aimed to validate VIRSTA and PREDICT scores for predicting the risk of IE in Colombian patients with SAB and, consequently, to determine the need for echocardiography. Methodology: Cohort of patients hospitalized with SAB in two high complexity institutions in Medellin, Colombia, between 2012-2018. The diagnosis of IE was established based on the modified Duke criteria. The VIRSTA and PREDICT scores were calculated from the clinical records, and their operational performance was calculated. Results: The final analysis included 922 patients, 62 (6.7%) of whom were diagnosed with IE. The frequency of IE in patients with a negative VIRSTA scale was 0.44% (2/454). The frequency of IE in patients with a negative PREDICT scale on day 5 was 4.8% (30/622). The sensitivity and negative predictive value (NPV) of the VIRSTA scale was 96.7% and 99.5%, respectively. For the PREDICT scale on day 5, the sensitivity and NPV were 51.6% and 95.1%, respectively. The discrimination, given by the area under the ROC curve (AUC), was 0.86 for VIRSTA and 0.64 for PREDICT. Conclusions: In patients with negative VIRSTA, screening echocardiography may be unnecessary due to the low frequency of IE. In PREDICT-negative patients, despite the low frequency of IE, it is not safe to omit echocardiography. Mención de responsabilidad : Juan Sebastián Peinado-Acevedo, Juan José Hurtado-Guerra, Carolina Hincapié, Juanita Mesa-Abad, José Roberto Uribe-Delgado, Santiago Giraldo-Ramírez, Paula A Lengerke-Diaz, Fabián Jaimes Referencia : Clin Infect Dis. 2021 Sep 7;73(5):e1151-e1157. DOI (Digital Object Identifier) : 10.1093/cid/ciaa1844 PMID : 33537758 En línea : https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa1844/6127448 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5774 Validation of VIRSTA and Predicting Risk of Endocarditis Using a Clinical Tool (PREDICT) Scores to Determine the Priority of Echocardiography in Patients With Staphylococcus aureus Bacteremia [documento electrónico] / Juan Sebastián Peinado Acevedo, . - 2021.
Accompagne Reply to Karakonstantis, et al; Zervou and Zacharioudakis; and Rasmussen, et al / Juan Sebastián Peinado Acevedo
Obra : Clinical Infectious Diseases
Idioma : Inglés (eng)
Palabras clave : Bacteremia Echocardiography Endocarditis Staphylococcal Infections Staphylococcus aureus Resumen : Introduction: Infective endocarditis (IE) secondary to Staphylococcus aureus bacteremia (SAB) has high morbidity and mortality. The systematic use of echocardiography in SAB is controversial. We aimed to validate VIRSTA and PREDICT scores for predicting the risk of IE in Colombian patients with SAB and, consequently, to determine the need for echocardiography. Methodology: Cohort of patients hospitalized with SAB in two high complexity institutions in Medellin, Colombia, between 2012-2018. The diagnosis of IE was established based on the modified Duke criteria. The VIRSTA and PREDICT scores were calculated from the clinical records, and their operational performance was calculated. Results: The final analysis included 922 patients, 62 (6.7%) of whom were diagnosed with IE. The frequency of IE in patients with a negative VIRSTA scale was 0.44% (2/454). The frequency of IE in patients with a negative PREDICT scale on day 5 was 4.8% (30/622). The sensitivity and negative predictive value (NPV) of the VIRSTA scale was 96.7% and 99.5%, respectively. For the PREDICT scale on day 5, the sensitivity and NPV were 51.6% and 95.1%, respectively. The discrimination, given by the area under the ROC curve (AUC), was 0.86 for VIRSTA and 0.64 for PREDICT. Conclusions: In patients with negative VIRSTA, screening echocardiography may be unnecessary due to the low frequency of IE. In PREDICT-negative patients, despite the low frequency of IE, it is not safe to omit echocardiography. Mención de responsabilidad : Juan Sebastián Peinado-Acevedo, Juan José Hurtado-Guerra, Carolina Hincapié, Juanita Mesa-Abad, José Roberto Uribe-Delgado, Santiago Giraldo-Ramírez, Paula A Lengerke-Diaz, Fabián Jaimes Referencia : Clin Infect Dis. 2021 Sep 7;73(5):e1151-e1157. DOI (Digital Object Identifier) : 10.1093/cid/ciaa1844 PMID : 33537758 En línea : https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa1844/6127448 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5774 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001699 AC-2021-024 Archivo digital Producción Científica Artículos científicos Disponible