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Early stimulated thyroglobulin after thyroidectomy for thyroid cancer predicts pre-radioiodine therapy thyroglobulin values / Julio Andrés Valencia Ferro  

Público ISBD Título : Early stimulated thyroglobulin after thyroidectomy for thyroid cancer predicts pre-radioiodine therapy thyroglobulin values Tipo de documento : documento electrónico Autores : Julio Andrés Valencia Ferro, Fecha de publicación : 2022 Títulos uniformes : Minerva Endocrinology Idioma : Inglés (eng) Palabras clave : Thyroid neoplasms  Thyroglobulin  Thyroidectomy Resumen : Introduction: Follow-up of patients who undergo a total thyroidectomy is performed with thyroglobulin (Tg), and anti-thyroglobulin antibodies (AbTg). The objective of RAI adjuvant therapy is to negativize Tg to undetectable levels to ease the follow-up. The objective of this study was to evaluate the correlation of serum Tg values measured 2 weeks after surgery with the Tg value prior to RAI adjuvant therapy in order to define its utility as a reliable predictor of pre-therapy Tg and as a potential predictor to avoid RAI adjuvant therapy. Methods: Retrospective analysis of a cohort recruited prospectively. Adult patients with thyroid carcinoma who underwent total thyroidectomy and classified as intermediate or high risk by ATA guidelines. All patients were left without levothyroxine support after surgery and for at least two weeks. We measured biochemical markers two-four weeks after thyroidectomy and before and after RAI. Results: We included 75 patients. Thirty-three (44.0%) patients were classified as ATA high risk. In the post-RAI scan, only 1 (1.3%) showed distant metastases. The comparison between early post-operative and pre-therapy Tg values showed that Tg decreased or remained stable at postoperative levels in 75 patients (100%). Conclusions: Postoperative Tg measurements are a reliable marker of pretherapy Tg levels in patients with intermediate- and high-risk thyroid carcinoma who are candidates for RAI adjuvant therapy. These results need correlation with outcomes and response to therapy in high-risk patients. Mención de responsabilidad : Julio Valencia, Jorge Jiménez, Alvaro Sanabria Referencia : Minerva Endocrinol (Torino). 2022 Jul 13. DOI (Digital Object Identifier) : 10.23736/S2724-6507.22.03813-1 PMID : 35822431 En línea : https://www.minervamedica.it/en/journals/minerva-endocrinology/article.php?cod=R [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6059 Early stimulated thyroglobulin after thyroidectomy for thyroid cancer predicts pre-radioiodine therapy thyroglobulin values [documento electrónico] / Julio Andrés Valencia Ferro,  . - 2022. Obra : Minerva Endocrinology Idioma : Inglés (eng) Palabras clave : Thyroid neoplasms  Thyroglobulin  Thyroidectomy Resumen : Introduction: Follow-up of patients who undergo a total thyroidectomy is performed with thyroglobulin (Tg), and anti-thyroglobulin antibodies (AbTg). The objective of RAI adjuvant therapy is to negativize Tg to undetectable levels to ease the follow-up. The objective of this study was to evaluate the correlation of serum Tg values measured 2 weeks after surgery with the Tg value prior to RAI adjuvant therapy in order to define its utility as a reliable predictor of pre-therapy Tg and as a potential predictor to avoid RAI adjuvant therapy. Methods: Retrospective analysis of a cohort recruited prospectively. Adult patients with thyroid carcinoma who underwent total thyroidectomy and classified as intermediate or high risk by ATA guidelines. All patients were left without levothyroxine support after surgery and for at least two weeks. We measured biochemical markers two-four weeks after thyroidectomy and before and after RAI. Results: We included 75 patients. Thirty-three (44.0%) patients were classified as ATA high risk. In the post-RAI scan, only 1 (1.3%) showed distant metastases. The comparison between early post-operative and pre-therapy Tg values showed that Tg decreased or remained stable at postoperative levels in 75 patients (100%). Conclusions: Postoperative Tg measurements are a reliable marker of pretherapy Tg levels in patients with intermediate- and high-risk thyroid carcinoma who are candidates for RAI adjuvant therapy. These results need correlation with outcomes and response to therapy in high-risk patients. Mención de responsabilidad : Julio Valencia, Jorge Jiménez, Alvaro Sanabria Referencia : Minerva Endocrinol (Torino). 2022 Jul 13. DOI (Digital Object Identifier) : 10.23736/S2724-6507.22.03813-1 PMID : 35822431 En línea : https://www.minervamedica.it/en/journals/minerva-endocrinology/article.php?cod=R [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6059

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DD001903	AC-2022-067	Archivo digital	Producción Científica	Artículos científicos	Disponible

The Bethesda system for reporting thyroid cytopathology in Colombia : Correlation with histopathological diagnoses in oncology and non-oncology institutions / Álvaro Enrique Sanabria Quiroga    

Público ISBD Título : The Bethesda system for reporting thyroid cytopathology in Colombia : Correlation with histopathological diagnoses in oncology and non-oncology institutions Tipo de documento : documento electrónico Autores : Álvaro Enrique Sanabria Quiroga, Fecha de publicación : 2015 Títulos uniformes : Journal of Cytology Idioma : Inglés (eng) Palabras clave : Bethesda system  biopsy  fine needle  multicenter study  pathology  terminology  thyroid cytopathology  thyroid gland  thyroid neoplasms Resumen : Aim: To determine the correlation between the results of thyroid fine-needle aspirations interpreted using the Bethesda system and final histopathological reports for patients at an oncology hospital (OH) and non-oncology hospitals (NOHs).Materials and Methods: A retrospective, cross-sectional, descriptive study was performed to compare the cytology and histopathology results for patients with thyroid nodules in three Colombian hospitals. The final correlation of diagnoses between the two methods is reported. In Colombia, the health system provides the existence of general care hospitals and hospitals specializing in care of patients with cancer.Results: A total of 196 reports were reviewed, of which 53% were from OH and 47% were from NOHs. A greater proportion of category V (37.5%) was diagnosed at the OH, whereas NOHs diagnosed a greater proportion of category II (42.3%). The global correlation between diagnoses made using cytology and histopathology was 93.3% for categories V and VI (based on the final malignant diagnosis) and 86.9% for benign category II. Significant differences between institution types were observed when category IV and V and malignant histopathology were compared (56.3% OH vs. 23.5% NOH; P = 0.05 for category IV, 97.4% OH vs. 82.3% NOH; P = 0.03 for category V), while no significant difference between institution types was observed when category II and final benign diagnosis were compared (P = 0.6).Conclusions: The Bethesda system for thyroid cytology correlates adequately with final histopathological diagnosis in Colombia. Significant differences were identified in the diagnostic correlation for malignant lesions between the OH and NOHs in categories IV and V caused by selection bias of the population. Mención de responsabilidad : Mario Alexander Melo-Uribe, Álvaro Sanabria, Alfredo Romero-Rojas, Gabriel Pérez, Elga Johanna Vargas, María Claudia Abaúnza, Víctor Gutiérrez Referencia : J Cytol. 2015 Jan-Mar;32(1):12-6. DOI (Digital Object Identifier) : 10.4103/0970-9371.155224. PMID : 25948937 Derechos de uso : CC BY-NC-SA En línea : http://www.jcytol.org/article.asp?issn=0970-9371;year=2015;volume=32;issue=1;spa [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3900 The Bethesda system for reporting thyroid cytopathology in Colombia : Correlation with histopathological diagnoses in oncology and non-oncology institutions [documento electrónico] / Álvaro Enrique Sanabria Quiroga,  . - 2015. Obra : Journal of Cytology Idioma : Inglés (eng) Palabras clave : Bethesda system  biopsy  fine needle  multicenter study  pathology  terminology  thyroid cytopathology  thyroid gland  thyroid neoplasms Resumen : Aim: To determine the correlation between the results of thyroid fine-needle aspirations interpreted using the Bethesda system and final histopathological reports for patients at an oncology hospital (OH) and non-oncology hospitals (NOHs).Materials and Methods: A retrospective, cross-sectional, descriptive study was performed to compare the cytology and histopathology results for patients with thyroid nodules in three Colombian hospitals. The final correlation of diagnoses between the two methods is reported. In Colombia, the health system provides the existence of general care hospitals and hospitals specializing in care of patients with cancer.Results: A total of 196 reports were reviewed, of which 53% were from OH and 47% were from NOHs. A greater proportion of category V (37.5%) was diagnosed at the OH, whereas NOHs diagnosed a greater proportion of category II (42.3%). The global correlation between diagnoses made using cytology and histopathology was 93.3% for categories V and VI (based on the final malignant diagnosis) and 86.9% for benign category II. Significant differences between institution types were observed when category IV and V and malignant histopathology were compared (56.3% OH vs. 23.5% NOH; P = 0.05 for category IV, 97.4% OH vs. 82.3% NOH; P = 0.03 for category V), while no significant difference between institution types was observed when category II and final benign diagnosis were compared (P = 0.6).Conclusions: The Bethesda system for thyroid cytology correlates adequately with final histopathological diagnosis in Colombia. Significant differences were identified in the diagnostic correlation for malignant lesions between the OH and NOHs in categories IV and V caused by selection bias of the population. Mención de responsabilidad : Mario Alexander Melo-Uribe, Álvaro Sanabria, Alfredo Romero-Rojas, Gabriel Pérez, Elga Johanna Vargas, María Claudia Abaúnza, Víctor Gutiérrez Referencia : J Cytol. 2015 Jan-Mar;32(1):12-6. DOI (Digital Object Identifier) : 10.4103/0970-9371.155224. PMID : 25948937 Derechos de uso : CC BY-NC-SA En línea : http://www.jcytol.org/article.asp?issn=0970-9371;year=2015;volume=32;issue=1;spa [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3900

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