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How many adults with temporal epilepsy have a mild course and do not require epilepsy surgery? / Lady Diana Ladino Malagón  

Público ISBD Título : How many adults with temporal epilepsy have a mild course and do not require epilepsy surgery? Tipo de documento : documento electrónico Autores : Lady Diana Ladino Malagón, Fecha de publicación : 2016 Títulos uniformes : Epileptic Disorders Idioma : Inglés (eng) Palabras clave : Adult epilepsy  benign temporal epilepsy  mild course  prognosis  severe course  temporal lobe epilepsy Resumen : Temporal lobe epilepsy (TLE) is the most common type of drug-resistant epilepsy in adults and commonly requires surgical treatment. While an overwhelming preponderance of literature supports the notion that a large percentage of patients with TLE benefit from surgery, there is a paucity of outcome data on patients who demonstrate a sustained response to pharmacological treatment. In this study, we present an adult cohort of patients with TLE, with the purpose of identifying the proportion of patients with a mild course of the disease, as well as potential risk factors. A prospective cohort study of all patients with TLE assessed and followed by the Saskatchewan Epilepsy Program, from 1 March 2007 to Jan 29(th) 2014. Patients were dichotomized as having a mild (seizure freedom without surgical intervention) or severe (surgical intervention required and/or failure to achieve seizure remission) course. Descriptive statistics, odds ratios and confidence intervals were calculated to identify predictors of seizure freedom. The cohort consisted of 159 patients. Mean patient age at last follow-up visit was 46±14.4 (range: 19-88) years. Mean follow-up period was 43.4±22.6 (6 to 84) months. Forty-six patients (29%) demonstrated mild-course TLE while 113 (71%) had a severe course of TLE. Patients with a mild course of TLE were more likely to be older (p = 0.002), have late-onset epilepsy (p Mención de responsabilidad : Lizbeth Hernández-Ronquillo, Samantha Buckley, Lady Diana Ladino, Adam Wu, Farzad Moien-Afshari, Syed Aa Rizvi, Jose F Téllez-Zenteno Referencia : Epileptic Disord. 2016 Jun 1;18(2):137-47. DOI (Digital Object Identifier) : 10.1684/epd.2016.0822 PMID : 27100050 En línea : https://www.jle.com/fr/revues/epd/e-docs/how_many_adults_with_temporal_epilepsy_ [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3983 How many adults with temporal epilepsy have a mild course and do not require epilepsy surgery? [documento electrónico] / Lady Diana Ladino Malagón,  . - 2016. Obra : Epileptic Disorders Idioma : Inglés (eng) Palabras clave : Adult epilepsy  benign temporal epilepsy  mild course  prognosis  severe course  temporal lobe epilepsy Resumen : Temporal lobe epilepsy (TLE) is the most common type of drug-resistant epilepsy in adults and commonly requires surgical treatment. While an overwhelming preponderance of literature supports the notion that a large percentage of patients with TLE benefit from surgery, there is a paucity of outcome data on patients who demonstrate a sustained response to pharmacological treatment. In this study, we present an adult cohort of patients with TLE, with the purpose of identifying the proportion of patients with a mild course of the disease, as well as potential risk factors. A prospective cohort study of all patients with TLE assessed and followed by the Saskatchewan Epilepsy Program, from 1 March 2007 to Jan 29(th) 2014. Patients were dichotomized as having a mild (seizure freedom without surgical intervention) or severe (surgical intervention required and/or failure to achieve seizure remission) course. Descriptive statistics, odds ratios and confidence intervals were calculated to identify predictors of seizure freedom. The cohort consisted of 159 patients. Mean patient age at last follow-up visit was 46±14.4 (range: 19-88) years. Mean follow-up period was 43.4±22.6 (6 to 84) months. Forty-six patients (29%) demonstrated mild-course TLE while 113 (71%) had a severe course of TLE. Patients with a mild course of TLE were more likely to be older (p = 0.002), have late-onset epilepsy (p Mención de responsabilidad : Lizbeth Hernández-Ronquillo, Samantha Buckley, Lady Diana Ladino, Adam Wu, Farzad Moien-Afshari, Syed Aa Rizvi, Jose F Téllez-Zenteno Referencia : Epileptic Disord. 2016 Jun 1;18(2):137-47. DOI (Digital Object Identifier) : 10.1684/epd.2016.0822 PMID : 27100050 En línea : https://www.jle.com/fr/revues/epd/e-docs/how_many_adults_with_temporal_epilepsy_ [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3983

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Código de barras	Número de Ubicación	Tipo de medio	Ubicación	Sección	Estado
DD000575	AC-2016-050	Archivo digital	Producción Científica	Artículos científicos	Disponible