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Título : DICER1 gene mutations in endocrine tumors Tipo de documento : documento electrónico Autores : Luis Vicente Syro Moreno, Fecha de publicación : 2018 Títulos uniformes : Endocrine Related Cancer Idioma : Inglés (eng) Palabras clave : DICER1 endocrine tumors mutation neoplasms pathology Resumen : In this review, the importance of the DICER1 gene in the function of endocrine cells is discussed. There is conclusive evidence that DICER1 mutations play a crucial role in the development, progression, cell proliferation, therapeutic responsiveness and behavior of several endocrine tumors. We review the literature of DICER1 gene mutations in thyroid, parathyroid, pituitary, pineal gland, endocrine pancreas, paragangliomas, medullary, adrenocortical, ovarian and testicular tumors. Although significant progress has been made during the last few years, much more work is needed to fully understand the significance of DICER1 mutations. Mención de responsabilidad : Michael Solarski, Fabio Rotondo, William D Foulkes, John R Priest, Luis V Syro, Henriett Butz, Michael D Cusimano, Kalman Kovacs Referencia : Endocr Relat Cancer. 2018 Mar;25(3):R197-R208. DOI (Digital Object Identifier) : 10.1530/ERC-17-0509 PMID : 29330195 En línea : https://erc.bioscientifica.com/view/journals/erc/25/3/ERC-17-0509.xml Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4195 DICER1 gene mutations in endocrine tumors [documento electrónico] / Luis Vicente Syro Moreno, . - 2018.
Obra : Endocrine Related Cancer
Idioma : Inglés (eng)
Palabras clave : DICER1 endocrine tumors mutation neoplasms pathology Resumen : In this review, the importance of the DICER1 gene in the function of endocrine cells is discussed. There is conclusive evidence that DICER1 mutations play a crucial role in the development, progression, cell proliferation, therapeutic responsiveness and behavior of several endocrine tumors. We review the literature of DICER1 gene mutations in thyroid, parathyroid, pituitary, pineal gland, endocrine pancreas, paragangliomas, medullary, adrenocortical, ovarian and testicular tumors. Although significant progress has been made during the last few years, much more work is needed to fully understand the significance of DICER1 mutations. Mención de responsabilidad : Michael Solarski, Fabio Rotondo, William D Foulkes, John R Priest, Luis V Syro, Henriett Butz, Michael D Cusimano, Kalman Kovacs Referencia : Endocr Relat Cancer. 2018 Mar;25(3):R197-R208. DOI (Digital Object Identifier) : 10.1530/ERC-17-0509 PMID : 29330195 En línea : https://erc.bioscientifica.com/view/journals/erc/25/3/ERC-17-0509.xml Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4195 Reserva
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