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Enlace permanente de la investigaciónSuccessful multiple-exchange peritoneal dialysis in a patient with severe hematological toxicity by methotrexate: case report and literature review / Arbey Aristizabal Álzate ; John Fredy Nieto Ríos ; Catalina Ocampo Kohn ; Gustavo Adolfo Zuluaga Valencia
Título : Successful multiple-exchange peritoneal dialysis in a patient with severe hematological toxicity by methotrexate: case report and literature review Tipo de documento : documento electrónico Autores : Arbey Aristizabal Álzate, ; John Fredy Nieto Ríos, ; Catalina Ocampo Kohn, ; Gustavo Adolfo Zuluaga Valencia, Fecha de publicación : 2019 Títulos uniformes : Brazilian Journal of Nephrology Idioma : Inglés (eng) Palabras clave : Methotrexate pancytopenia renal insufficiency peritoneal dialysis Resumen : Methotrexate is an effective medication to control several diseases; however, it can be very toxic, being myelosuppression one of its main adverse effects, which increases in severity and frequency in patients with renal failure. We present the case of a 68-year-old man with chronic, end-stage renal disease associated with ANCA vasculitis, under treatment with peritoneal dialysis, who received the medication at a low dose, indicated by disease activity, which presented as a complication with severe pancytopenia with mucositis that improved with support measures and multiple-exchange peritoneal dialysis. We reviewed 20 cases published to date of pancytopenia associated with methotrexate in patients on dialysis and found high morbidity and mortality, which is why its use in this type of patient is not recommended. However, when this complication occurs, a therapeutic option could be the use of multiple-exchange peritoneal dialysis in addition to supportive therapy for drug-related toxicity, although it is recognized that studies are required to show the role of multiple-exchange peritoneal dialysis in the removal of this medication. Mención de responsabilidad : Arbey Aristizabal-Alzate, John Fredy Nieto-Rios, Catalina Ocampo-Kohn, Lina Maria Serna-Higuita, Diana Carolina Bello-Marquez, Gustavo Adolfo Zuluaga-Valencia Referencia : J Bras Nefrol. 2018 Sep 21. pii: S0101-28002018005003402. DOI (Digital Object Identifier) : 10.1590/2175-8239-JBN-2018-0095 PMID : 30281061 Derechos de uso : CC BY En línea : http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002018005003402&l [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4133 Successful multiple-exchange peritoneal dialysis in a patient with severe hematological toxicity by methotrexate: case report and literature review [documento electrónico] / Arbey Aristizabal Álzate, ; John Fredy Nieto Ríos, ; Catalina Ocampo Kohn, ; Gustavo Adolfo Zuluaga Valencia, . - 2019.
Obra : Brazilian Journal of Nephrology
Idioma : Inglés (eng)
Palabras clave : Methotrexate pancytopenia renal insufficiency peritoneal dialysis Resumen : Methotrexate is an effective medication to control several diseases; however, it can be very toxic, being myelosuppression one of its main adverse effects, which increases in severity and frequency in patients with renal failure. We present the case of a 68-year-old man with chronic, end-stage renal disease associated with ANCA vasculitis, under treatment with peritoneal dialysis, who received the medication at a low dose, indicated by disease activity, which presented as a complication with severe pancytopenia with mucositis that improved with support measures and multiple-exchange peritoneal dialysis. We reviewed 20 cases published to date of pancytopenia associated with methotrexate in patients on dialysis and found high morbidity and mortality, which is why its use in this type of patient is not recommended. However, when this complication occurs, a therapeutic option could be the use of multiple-exchange peritoneal dialysis in addition to supportive therapy for drug-related toxicity, although it is recognized that studies are required to show the role of multiple-exchange peritoneal dialysis in the removal of this medication. Mención de responsabilidad : Arbey Aristizabal-Alzate, John Fredy Nieto-Rios, Catalina Ocampo-Kohn, Lina Maria Serna-Higuita, Diana Carolina Bello-Marquez, Gustavo Adolfo Zuluaga-Valencia Referencia : J Bras Nefrol. 2018 Sep 21. pii: S0101-28002018005003402. DOI (Digital Object Identifier) : 10.1590/2175-8239-JBN-2018-0095 PMID : 30281061 Derechos de uso : CC BY En línea : http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002018005003402&l [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4133 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000744 AC-2018-031 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2018-031.pdfAdobe Acrobat PDF
Título : Urinary tract infection leading to hospital admission during the first year after kidney transplantation: A retrospective cohort study Tipo de documento : documento electrónico Autores : Fabián Alberto Jaimes Barragán, Fecha de publicación : 2016 Títulos uniformes : Transplantation Reports Idioma : Inglés (eng) Palabras clave : CKD Chronic kidney disease CKF Chronic kidney failure ESRD end stage renal disease HD hemodialysis KTR kidney transplant recipients MDR Multidrug resistant MMF mycophenolate mofetil mTOR mammalian target of rapamycin PD peritoneal dialysis RRT renal replacement therapy UTI Urinary tract infection TMP/SMX Trimethoprim-sulfamethoxazole XDR Extensively drug-resistant Resumen : Introduction: Urinary tract infection (UTI) is the most common infectious problem in kidney transplant recipients (KTR). It has been associated with risk factors inherent to the transplant and it could negatively affect clinical outcomes. The aim of this study was to describe demographic, clinical and microbiological characteristics of patients with UTI. Methods: We underwent a retrospective study reviewing the database of kidney transplants patients in a national reference center in Colombia. We included patients admitted for inpatient treatment related to urinary tract infection in the first year after transplantation. Results: We describe clinical information from 65 patients, the mean age was 46 years, the most common comorbidity was hypertension (n=48/62, 77.4%) followed by diabetes mellitus (n=11/62, 17.7%); 77% (n=50/65) of the infections were diagnosed in the first 6 months after transplant and 70% (n=45/65) had pyelonephritis. Acute dysfunction of the graft was the most common complication in 59% (n=33/56) of cases. The most common etiological agent described was E. coli in 67% (n=37/55) of patients followed by Klebsiella pneumoniae (n=13/55). Bacteremia was present in 25% of cases. Infection with extended-spectrum betalactamases producing bacteria was present in 42% (n=18/42) of our isolations and multidrug resistance was documented in 39% (n=21/54) of isolates. Conclusion: Most UTI leading to hospitalization in KTR occur in the first six months. Pyelonephritis explains the majority of clinical diagnosis. The rate of blood stream infections and multidrug resistance bacteria is high, justifying an empiric broad-spectrum antibiotic treatment. Mención de responsabilidad : Santiago Giraldo-Ramírez, Oscar Emilio Díaz-Portilla, Andrés Felipe Miranda-Arboleda, Jorge Henao-Sierra, Lina María Echeverri-Toro, Fabian Jaimes DOI (Digital Object Identifier) : 10.1016/j.tpr.2016.09.001 Derechos de uso : CC BY-NC-ND En línea : https://linkinghub.elsevier.com/retrieve/pii/S2451959616300154 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4616 Urinary tract infection leading to hospital admission during the first year after kidney transplantation: A retrospective cohort study [documento electrónico] / Fabián Alberto Jaimes Barragán, . - 2016.
Obra : Transplantation Reports
Idioma : Inglés (eng)
Palabras clave : CKD Chronic kidney disease CKF Chronic kidney failure ESRD end stage renal disease HD hemodialysis KTR kidney transplant recipients MDR Multidrug resistant MMF mycophenolate mofetil mTOR mammalian target of rapamycin PD peritoneal dialysis RRT renal replacement therapy UTI Urinary tract infection TMP/SMX Trimethoprim-sulfamethoxazole XDR Extensively drug-resistant Resumen : Introduction: Urinary tract infection (UTI) is the most common infectious problem in kidney transplant recipients (KTR). It has been associated with risk factors inherent to the transplant and it could negatively affect clinical outcomes. The aim of this study was to describe demographic, clinical and microbiological characteristics of patients with UTI. Methods: We underwent a retrospective study reviewing the database of kidney transplants patients in a national reference center in Colombia. We included patients admitted for inpatient treatment related to urinary tract infection in the first year after transplantation. Results: We describe clinical information from 65 patients, the mean age was 46 years, the most common comorbidity was hypertension (n=48/62, 77.4%) followed by diabetes mellitus (n=11/62, 17.7%); 77% (n=50/65) of the infections were diagnosed in the first 6 months after transplant and 70% (n=45/65) had pyelonephritis. Acute dysfunction of the graft was the most common complication in 59% (n=33/56) of cases. The most common etiological agent described was E. coli in 67% (n=37/55) of patients followed by Klebsiella pneumoniae (n=13/55). Bacteremia was present in 25% of cases. Infection with extended-spectrum betalactamases producing bacteria was present in 42% (n=18/42) of our isolations and multidrug resistance was documented in 39% (n=21/54) of isolates. Conclusion: Most UTI leading to hospitalization in KTR occur in the first six months. Pyelonephritis explains the majority of clinical diagnosis. The rate of blood stream infections and multidrug resistance bacteria is high, justifying an empiric broad-spectrum antibiotic treatment. Mención de responsabilidad : Santiago Giraldo-Ramírez, Oscar Emilio Díaz-Portilla, Andrés Felipe Miranda-Arboleda, Jorge Henao-Sierra, Lina María Echeverri-Toro, Fabian Jaimes DOI (Digital Object Identifier) : 10.1016/j.tpr.2016.09.001 Derechos de uso : CC BY-NC-ND En línea : https://linkinghub.elsevier.com/retrieve/pii/S2451959616300154 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4616 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001114 AC-2016-095 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2016-095.pdfAdobe Acrobat PDF
Título : Peritoneal dialysis-related peritonitis: twenty-seven years of experience in a Colombian medical center Otros títulos : Peritonitis asociada a la diálisis peritoneal, 27 años de experiencia en un único centro, Medellín, Colombia Tipo de documento : documento electrónico Autores : John Fredy Nieto Ríos, ; Lina Maria Serna Higuita, Fecha de publicación : 2014 Títulos uniformes : Nefrología Idioma : Inglés (eng) Palabras clave : Peritoneal dialysis peritonitis Colombia Latin America Resumen : Peritonitis has been the most common complication of continues ambulatory peritoneal dialysis (CAPD) since it was first implemented, and it remains the leading cause of treatment failure and transfer to other renal replacement therapies. This study presents a Colombian series with a total of 2469 episodes of peritonitis in 914 patients from a cohort of 1,497 patients on PD, who were followed for almost three decades at a single center. This is the largest Latin American series of patients with PD-related peritonitis. Objective: To describe the CAPD-related peritonitis in a cohort of patients followed for 27 years at a single center, and compare the results with those observed elsewhere in the world. Study Design: Prospective study of incident patients on CAPD from March 1981 to December 2008. Results: In our center, the rate of peritonitis has been steady between 0.8 and 0.9 since 1981 and no significant changes have been noticed in the 27 years of follow up. The rate remains similar to that described nowadays by other large dialysis centers in the world, which have reported significant improvements in recent decades. No significant differences were found in the isolates of gram-positive and gram-negative microorganisms or fungi with respect to those reported by other large series, or in the frequency of culture-negative peritonitis. Conclusion: This study presents the largest Latin American series of patients with CAPD-related peritonitis with a total of 2,469 patients. In this study, the rate of CAPD-related peritonitis remained almost the same during the three decades of observation despite having used three different CAPD systems. Our hypothesis is that the socio-economic conditions of the patients admitted for peritoneal dialysis influences the rate of peritonitis. Mención de responsabilidad : John F Nieto-Ríos, James S Díaz-Betancur, Mario Arbeláez-Gómez, Álvaro García-García, Joaquín Rodelo-Ceballos, Alberto Reino-Buelvas, Lina M Serna-Higuita, Jorge E Henao-Sierra Referencia : Nefrologia. 2014;34(1):88-95. DOI (Digital Object Identifier) : 10.3265/Nefrologia.pre2013.Nov.12002 PMID : 24336639 Derechos de uso : CC BY-NC-ND En línea : https://www.revistanefrologia.com/es-linkresolver-peritonitis-asociada-dialisis- [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3763 Peritoneal dialysis-related peritonitis: twenty-seven years of experience in a Colombian medical center = Peritonitis asociada a la diálisis peritoneal, 27 años de experiencia en un único centro, Medellín, Colombia [documento electrónico] / John Fredy Nieto Ríos, ; Lina Maria Serna Higuita, . - 2014.
Obra : Nefrología
Idioma : Inglés (eng)
Palabras clave : Peritoneal dialysis peritonitis Colombia Latin America Resumen : Peritonitis has been the most common complication of continues ambulatory peritoneal dialysis (CAPD) since it was first implemented, and it remains the leading cause of treatment failure and transfer to other renal replacement therapies. This study presents a Colombian series with a total of 2469 episodes of peritonitis in 914 patients from a cohort of 1,497 patients on PD, who were followed for almost three decades at a single center. This is the largest Latin American series of patients with PD-related peritonitis. Objective: To describe the CAPD-related peritonitis in a cohort of patients followed for 27 years at a single center, and compare the results with those observed elsewhere in the world. Study Design: Prospective study of incident patients on CAPD from March 1981 to December 2008. Results: In our center, the rate of peritonitis has been steady between 0.8 and 0.9 since 1981 and no significant changes have been noticed in the 27 years of follow up. The rate remains similar to that described nowadays by other large dialysis centers in the world, which have reported significant improvements in recent decades. No significant differences were found in the isolates of gram-positive and gram-negative microorganisms or fungi with respect to those reported by other large series, or in the frequency of culture-negative peritonitis. Conclusion: This study presents the largest Latin American series of patients with CAPD-related peritonitis with a total of 2,469 patients. In this study, the rate of CAPD-related peritonitis remained almost the same during the three decades of observation despite having used three different CAPD systems. Our hypothesis is that the socio-economic conditions of the patients admitted for peritoneal dialysis influences the rate of peritonitis. Mención de responsabilidad : John F Nieto-Ríos, James S Díaz-Betancur, Mario Arbeláez-Gómez, Álvaro García-García, Joaquín Rodelo-Ceballos, Alberto Reino-Buelvas, Lina M Serna-Higuita, Jorge E Henao-Sierra Referencia : Nefrologia. 2014;34(1):88-95. DOI (Digital Object Identifier) : 10.3265/Nefrologia.pre2013.Nov.12002 PMID : 24336639 Derechos de uso : CC BY-NC-ND En línea : https://www.revistanefrologia.com/es-linkresolver-peritonitis-asociada-dialisis- [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3763 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000338 AC-2014-004 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2014-004.pdfAdobe Acrobat PDF
