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Treatment of post-biopsy arteriovenous fistula of a renal graft by selective embolization / José Miguel Hidalgo Oviedo ; Sergio Álvarez Vallejo ; Arbey Aristizabal Álzate ; Gustavo Adolfo Zuluaga Valencia ; John Fredy Nieto Ríos
Título : Treatment of post-biopsy arteriovenous fistula of a renal graft by selective embolization Tipo de documento : documento electrónico Autores : José Miguel Hidalgo Oviedo, ; Sergio Álvarez Vallejo, ; Arbey Aristizabal Álzate, ; Gustavo Adolfo Zuluaga Valencia, ; John Fredy Nieto Ríos, Fecha de publicación : 2021 Títulos uniformes : Indian Journal of Nephrology Idioma : Inglés (eng) Palabras clave : Arteriovenous fistula kidney transplantation graft biopsy graft rejection selective embolization Resumen : The development of an arteriovenous fistula (AVF) after renal graft biopsy is a rare complication, it is associated in most cases with spontaneous resolution. However, interventional therapies are required in some cases, to prevent graft loss. Selective embolization has been described as an alternative treatment. In the present study, we describes our experience on AVF after biopsy in kidney transplant patients, which was managed with selective embolization. From 2005 to 2015, a total of 452 kidney transplant biopsies were performed, 12 had an AVF requiring embolization. In 92% of cases, this was successful. Beforehand, mean serum creatinine levels were 2.45 mg/dL, after the procedure, that increased to 3.05, however, 3 months later, mean creatinine levels dropped to 1.85 mg/dL. Graft survival after 2 follow-up years was 72%. Our experience demonstrates that selective embolization of the AVF after kidney transplant biopsy is a safe procedure, and that transplant function can be maintained in patients with this complication. Mención de responsabilidad : Lina M Serna-Higuita, Monica Zuluaga-Quintero, Jose M Hidalgo-Oviedo, Sergio Alvarez Vallejo, Arbey Aristizabal-Alzate, Gustavo A Zuluaga-Valencia, John F Nieto-Ríos Referencia : Indian J Nephrol. Mar-Apr 2021;31(2):201-204. DOI (Digital Object Identifier) : 10.4103/ijn.IJN_351_19 PMID : 34267449 En línea : https://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2021;volume=31;is [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5777 Treatment of post-biopsy arteriovenous fistula of a renal graft by selective embolization [documento electrónico] / José Miguel Hidalgo Oviedo, ; Sergio Álvarez Vallejo, ; Arbey Aristizabal Álzate, ; Gustavo Adolfo Zuluaga Valencia, ; John Fredy Nieto Ríos, . - 2021.
Obra : Indian Journal of Nephrology
Idioma : Inglés (eng)
Palabras clave : Arteriovenous fistula kidney transplantation graft biopsy graft rejection selective embolization Resumen : The development of an arteriovenous fistula (AVF) after renal graft biopsy is a rare complication, it is associated in most cases with spontaneous resolution. However, interventional therapies are required in some cases, to prevent graft loss. Selective embolization has been described as an alternative treatment. In the present study, we describes our experience on AVF after biopsy in kidney transplant patients, which was managed with selective embolization. From 2005 to 2015, a total of 452 kidney transplant biopsies were performed, 12 had an AVF requiring embolization. In 92% of cases, this was successful. Beforehand, mean serum creatinine levels were 2.45 mg/dL, after the procedure, that increased to 3.05, however, 3 months later, mean creatinine levels dropped to 1.85 mg/dL. Graft survival after 2 follow-up years was 72%. Our experience demonstrates that selective embolization of the AVF after kidney transplant biopsy is a safe procedure, and that transplant function can be maintained in patients with this complication. Mención de responsabilidad : Lina M Serna-Higuita, Monica Zuluaga-Quintero, Jose M Hidalgo-Oviedo, Sergio Alvarez Vallejo, Arbey Aristizabal-Alzate, Gustavo A Zuluaga-Valencia, John F Nieto-Ríos Referencia : Indian J Nephrol. Mar-Apr 2021;31(2):201-204. DOI (Digital Object Identifier) : 10.4103/ijn.IJN_351_19 PMID : 34267449 En línea : https://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2021;volume=31;is [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5777 Reserva
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Título : Acertive decision in older adult with coronavirus Tipo de documento : documento electrónico Autores : Mónica Zuluaga Quintero, Fecha de publicación : 2021 Títulos uniformes : Journal of Lung, Pulmonary & Respiratory Research Idioma : Inglés (eng) Mención de responsabilidad : Mónica Zuluaga Quintero DOI (Digital Object Identifier) : 10.15406/jlprr.2021.08.00256 Derechos de uso : CC BY-NC En línea : https://medcraveonline.com/JLPRR/JLPRR-08-00256.pdf Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5809 Acertive decision in older adult with coronavirus [documento electrónico] / Mónica Zuluaga Quintero, . - 2021.
Obra : Journal of Lung, Pulmonary & Respiratory Research
Idioma : Inglés (eng)
Mención de responsabilidad : Mónica Zuluaga Quintero DOI (Digital Object Identifier) : 10.15406/jlprr.2021.08.00256 Derechos de uso : CC BY-NC En línea : https://medcraveonline.com/JLPRR/JLPRR-08-00256.pdf Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5809 Reserva
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2021-059Adobe Acrobat PDF ¿Carcinoma de mama o carcinoma de glándula sudorípara? Presentación de dos casos y análisis de la literatura / Gabriel Jaime Varela Aguirre
Título : ¿Carcinoma de mama o carcinoma de glándula sudorípara? Presentación de dos casos y análisis de la literatura Otros títulos : Breast carcinoma or sweat gland carcinoma? A report of two cases and a comparison with the literature Tipo de documento : documento electrónico Autores : Gabriel Jaime Varela Aguirre, Fecha de publicación : 2021 Títulos uniformes : Biomédica Idioma : Español (spa) Palabras clave : neoplasias de la mama neoplasias cutáneas glándulas apocrinas patología informes de casos Resumen : El carcinoma apocrino primario de glándula sudorípara es una neoplasia con una muy baja incidencia, que puede representar un reto diagnóstico, clínico e histológico, y un reto terapéutico local, adyuvante y de la enfermedad avanzada. La edad media de los pacientes es de alrededor de 67 años, y no se ha observado preferencia según el sexo. Se presenta con mayor frecuencia en las axilas y en el cuero cabelludo. Se caracteriza clínicamente por un lento crecimiento, aunque puede progresar agresivamente, con compromiso local, ganglionar y metastásico, principalmente, pulmonar, hepático y óseo. El tratamiento recomendado –una vez establecida la histología– consiste en una resección local amplia con un margen claro de 1 a 2 cm y linfadenectomía regional si se detectan ganglios clínicamente positivos. El tratamiento adyuvante (radioterapia o quimioterapia) y de la enfermedad avanzada no está claramente establecido. Se presentan dos pacientes de sexo femenino con sospecha inicial de cáncer de mama, en quienes se diagnosticó finalmente un carcinoma apocrino de glándula sudorípara. Mención de responsabilidad : Mauricio Luján, Gabriel Varela, Diego Morán Referencia : Biomedica. 2021 Sep 22;41(3):409-419. DOI (Digital Object Identifier) : 10.7705/biomedica.5758 PMID : 34559489 Derechos de uso : CC BY En línea : https://revistabiomedica.org/index.php/biomedica/article/view/5758 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5873 ¿Carcinoma de mama o carcinoma de glándula sudorípara? Presentación de dos casos y análisis de la literatura = Breast carcinoma or sweat gland carcinoma? A report of two cases and a comparison with the literature [documento electrónico] / Gabriel Jaime Varela Aguirre, . - 2021.
Obra : Biomédica
Idioma : Español (spa)
Palabras clave : neoplasias de la mama neoplasias cutáneas glándulas apocrinas patología informes de casos Resumen : El carcinoma apocrino primario de glándula sudorípara es una neoplasia con una muy baja incidencia, que puede representar un reto diagnóstico, clínico e histológico, y un reto terapéutico local, adyuvante y de la enfermedad avanzada. La edad media de los pacientes es de alrededor de 67 años, y no se ha observado preferencia según el sexo. Se presenta con mayor frecuencia en las axilas y en el cuero cabelludo. Se caracteriza clínicamente por un lento crecimiento, aunque puede progresar agresivamente, con compromiso local, ganglionar y metastásico, principalmente, pulmonar, hepático y óseo. El tratamiento recomendado –una vez establecida la histología– consiste en una resección local amplia con un margen claro de 1 a 2 cm y linfadenectomía regional si se detectan ganglios clínicamente positivos. El tratamiento adyuvante (radioterapia o quimioterapia) y de la enfermedad avanzada no está claramente establecido. Se presentan dos pacientes de sexo femenino con sospecha inicial de cáncer de mama, en quienes se diagnosticó finalmente un carcinoma apocrino de glándula sudorípara. Mención de responsabilidad : Mauricio Luján, Gabriel Varela, Diego Morán Referencia : Biomedica. 2021 Sep 22;41(3):409-419. DOI (Digital Object Identifier) : 10.7705/biomedica.5758 PMID : 34559489 Derechos de uso : CC BY En línea : https://revistabiomedica.org/index.php/biomedica/article/view/5758 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5873 Reserva
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2021-123Adobe Acrobat PDF
Título : End-of-life transfusions in patients with an oncological diagnosis Otros títulos : Transfusiones al final de la vida en pacientes con diagnóstico oncológico Tipo de documento : documento electrónico Autores : Juan Felipe Vargas Silva, Fecha de publicación : 2021 Títulos uniformes : Revista de la Sociedad Española del Dolor Idioma : Inglés (eng) Palabras clave : Blood transfusion hospice care quality of life cancer pain Resumen : Introduction: Cancer patients in terminal stages present symptoms related to anemia, other cytopenias, and coagulopathies that deteriorate the quality of life. These symptoms can be multicausal and do not improve in most cases. Objective: Describe the use of blood transfusions in the six months before death as an alternative palliative treatment in patients with an oncological diagnosis in the city of Medellin during the period 2013-2018. Methods: Retrospective cohort, in patients with a cancer diagnosis who received transfusions in the last six months of life, a non-probabilistic sampling of consecutive cases was executed. The analysis was carried out in SPSS, estimating absolute and relative frequencies and median with interquartile ranges. Results: Out of 3,254 medical records of cancer patients, 151 were included. The time to oncological diagnosis had a median of 2 years (IQR 1 and 3). The symptoms observed in patients before and after the first transfusion were pain, present in 32.1 % (46) and 16.9 % (25) respectively, besides drowsiness was distinguished in 25 % (36) before transfusion and 14.3 % (21) after. Finally, the clinical outcomes before and after the last transfusion prior to death, were a decrease in pain, asthenia/adynamia, drowsiness, among others. Conclusions: The findings of this research allow us to appreciate the current panorama in the institutions in which palliative care medical services are being provided and consider when to offer the blood products to a patient at the end of life as a therapeutic measure in the context of a human being cared by physicians. Mención de responsabilidad : AP Brome Uribe, LM Martínez Sánchez, L Herrera-Almanza, M Fonseca-Guzmán, C Durango-Sánchez, V Vasquez-Estrada, L Duque-Echeverri, A Morales-Montoya, ME Saavedra-Valencia, JF Vargas-Silva, SM Molina-Giraldo DOI (Digital Object Identifier) : 10.20986/resed.2022.3956/2021 Derechos de uso : CC BY-NC-ND En línea : https://www.resed.es/transfusiones-al-final-de-la-vida-en-pacientes-con-diagnost [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5991 End-of-life transfusions in patients with an oncological diagnosis = Transfusiones al final de la vida en pacientes con diagnóstico oncológico [documento electrónico] / Juan Felipe Vargas Silva, . - 2021.
Obra : Revista de la Sociedad Española del Dolor
Idioma : Inglés (eng)
Palabras clave : Blood transfusion hospice care quality of life cancer pain Resumen : Introduction: Cancer patients in terminal stages present symptoms related to anemia, other cytopenias, and coagulopathies that deteriorate the quality of life. These symptoms can be multicausal and do not improve in most cases. Objective: Describe the use of blood transfusions in the six months before death as an alternative palliative treatment in patients with an oncological diagnosis in the city of Medellin during the period 2013-2018. Methods: Retrospective cohort, in patients with a cancer diagnosis who received transfusions in the last six months of life, a non-probabilistic sampling of consecutive cases was executed. The analysis was carried out in SPSS, estimating absolute and relative frequencies and median with interquartile ranges. Results: Out of 3,254 medical records of cancer patients, 151 were included. The time to oncological diagnosis had a median of 2 years (IQR 1 and 3). The symptoms observed in patients before and after the first transfusion were pain, present in 32.1 % (46) and 16.9 % (25) respectively, besides drowsiness was distinguished in 25 % (36) before transfusion and 14.3 % (21) after. Finally, the clinical outcomes before and after the last transfusion prior to death, were a decrease in pain, asthenia/adynamia, drowsiness, among others. Conclusions: The findings of this research allow us to appreciate the current panorama in the institutions in which palliative care medical services are being provided and consider when to offer the blood products to a patient at the end of life as a therapeutic measure in the context of a human being cared by physicians. Mención de responsabilidad : AP Brome Uribe, LM Martínez Sánchez, L Herrera-Almanza, M Fonseca-Guzmán, C Durango-Sánchez, V Vasquez-Estrada, L Duque-Echeverri, A Morales-Montoya, ME Saavedra-Valencia, JF Vargas-Silva, SM Molina-Giraldo DOI (Digital Object Identifier) : 10.20986/resed.2022.3956/2021 Derechos de uso : CC BY-NC-ND En línea : https://www.resed.es/transfusiones-al-final-de-la-vida-en-pacientes-con-diagnost [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5991 Reserva
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AC-2021-156Adobe Acrobat PDF Psychogenic nonepileptic seizures in Latin America: A survey describing current practices / Lady Diana Ladino Malagón
Título : Psychogenic nonepileptic seizures in Latin America: A survey describing current practices Tipo de documento : documento electrónico Autores : Lady Diana Ladino Malagón, Fecha de publicación : 2021 Títulos uniformes : Epilepsy & Behavior Idioma : Inglés (eng) Palabras clave : Diagnosis Barriers Health services Nonepileptic seizures Psychotherapy Treatment Resumen : Objective: Psychogenic nonepileptic seizures (PNES) are one of the most common differential diagnoses of epilepsy. This study provides an overview of diagnostic and treatment services for patients with PNES across Latin America. Methods: In 2017–2018, clinicians practicing in Latin America with responsibilities for patients with PNES were contacted to respond to a survey regarding the management of this disorder developed by the International League Against Epilepsy (ILAE) PNES Task Force. Results: Three hundred and sixty responses from 17 Latin American countries were analyzed. Most respondents were neurologists (81%) under 40 years of age (61%). Fifty-seven percent of professionals stated that they personally diagnose PNES, but only 33% stated that they provide follow-up, and only 20% that they recommend treatment. Many participants (54%) characterized themselves as either unfamiliar with the diagnosis or inexperienced in arranging treatment. Most respondents reported having access to brain magnetic resonance imaging (MRI; 88%) and routine electroencephalogram (EEG; 71%), 64% have the access to video-EEG longer than 8 h, and 54% of professionals performed video-EEG to confirm PNES diagnoses. Although cognitive–behavioral therapy was recognized as the treatment of choice (by 82% of respondents), there was little access to it (60%). In contrast, a high proportion of respondents reported using antidepressant (67%), antiseizure (57%), and antipsychotic medications (54%) as treatments for PNES. Significance: This study reveals several deficiencies in the diagnosis and treatment of patients with PNES in Latin America. The barriers are reinforced by lack of knowledge among the specialists and poor healthcare system support. There is inadequate access to prolonged video-EEG and psychotherapy. An inappropriate use of antiseizure medicines seems commonplace, and there are low follow-up rates by neurologists after the diagnosis. Multidisciplinary guidelines are required to improve the approach of patients with PNES. Mención de responsabilidad : Lady Diana Ladino, Vanessa Benjumea-Cuartas, Yamile Calle-López, Juan Pablo Orozco-Hernández, Diana Marcela Castrillón-Velilla, Reydmar López-González, Anilu Daza-Restrepo, Mario Alberto Genel Castillo, Markus Reuber, Alyssa Denton, José F Tellez-Zenteno Referencia : Epilepsy Behav. 2021 Jan;114(Pt A):107150. DOI (Digital Object Identifier) : 10.1016/j.yebeh.2020.107150 PMID : 32507294 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1525505020303292 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5117 Psychogenic nonepileptic seizures in Latin America: A survey describing current practices [documento electrónico] / Lady Diana Ladino Malagón, . - 2021.
Obra : Epilepsy & Behavior
Idioma : Inglés (eng)
Palabras clave : Diagnosis Barriers Health services Nonepileptic seizures Psychotherapy Treatment Resumen : Objective: Psychogenic nonepileptic seizures (PNES) are one of the most common differential diagnoses of epilepsy. This study provides an overview of diagnostic and treatment services for patients with PNES across Latin America. Methods: In 2017–2018, clinicians practicing in Latin America with responsibilities for patients with PNES were contacted to respond to a survey regarding the management of this disorder developed by the International League Against Epilepsy (ILAE) PNES Task Force. Results: Three hundred and sixty responses from 17 Latin American countries were analyzed. Most respondents were neurologists (81%) under 40 years of age (61%). Fifty-seven percent of professionals stated that they personally diagnose PNES, but only 33% stated that they provide follow-up, and only 20% that they recommend treatment. Many participants (54%) characterized themselves as either unfamiliar with the diagnosis or inexperienced in arranging treatment. Most respondents reported having access to brain magnetic resonance imaging (MRI; 88%) and routine electroencephalogram (EEG; 71%), 64% have the access to video-EEG longer than 8 h, and 54% of professionals performed video-EEG to confirm PNES diagnoses. Although cognitive–behavioral therapy was recognized as the treatment of choice (by 82% of respondents), there was little access to it (60%). In contrast, a high proportion of respondents reported using antidepressant (67%), antiseizure (57%), and antipsychotic medications (54%) as treatments for PNES. Significance: This study reveals several deficiencies in the diagnosis and treatment of patients with PNES in Latin America. The barriers are reinforced by lack of knowledge among the specialists and poor healthcare system support. There is inadequate access to prolonged video-EEG and psychotherapy. An inappropriate use of antiseizure medicines seems commonplace, and there are low follow-up rates by neurologists after the diagnosis. Multidisciplinary guidelines are required to improve the approach of patients with PNES. Mención de responsabilidad : Lady Diana Ladino, Vanessa Benjumea-Cuartas, Yamile Calle-López, Juan Pablo Orozco-Hernández, Diana Marcela Castrillón-Velilla, Reydmar López-González, Anilu Daza-Restrepo, Mario Alberto Genel Castillo, Markus Reuber, Alyssa Denton, José F Tellez-Zenteno Referencia : Epilepsy Behav. 2021 Jan;114(Pt A):107150. DOI (Digital Object Identifier) : 10.1016/j.yebeh.2020.107150 PMID : 32507294 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1525505020303292 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5117 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001374 AC-2020-052 Archivo digital Producción Científica Artículos científicos Disponible Diabetes mellitus y COVID-19: fisiopatología y propuesta de tratamiento para el control glucémico en el tiempo de la pandemia / Carlos Esteban Builes Montaño ; Clara María Arango Toro
Título : Diabetes mellitus y COVID-19: fisiopatología y propuesta de tratamiento para el control glucémico en el tiempo de la pandemia Otros títulos : Diabetes mellitus and COVID-19: pathophysiology and treatment proposal for glycemic control at the time of the pandemic Tipo de documento : documento electrónico Autores : Carlos Esteban Builes Montaño, ; Clara María Arango Toro, Fecha de publicación : 2021 Títulos uniformes : Iatreia Idioma : Español (spa) Palabras clave : Coronavirus COVID-19 Diabetes Mellitus Glucosa Sanguínea Virus del SRAS Resumen : El coronavirus 2 del síndrome respiratorio agudo grave es el tercer betacoronavirus desde el año 2003 capaz de ocasionar una infección del tracto respiratorio inferior, llevando, en casos críticos, al síndrome de dificultad respiratoria aguda y la muerte. La edad avanzada, la hipertensión arterial y la diabetes mellitus son, entre otros, tres factores determinantes en los peores desenlaces clínicos. Múltiples mecanismos pueden explicar la mayor susceptibilidad de las personas diabéticas a las infecciones respiratorias. La hiperglucemia crónica altera tanto a la inmunidad humoral como al celular. Esta enfermedad predispone a la sobreexpresión de la proteína de la membrana celular que sirve como receptora del virus y a una respuesta inflamatoria exacerbada, aumentando el riesgo de una descompensación y de la aparición de crisis hiperglicémicas. Ante la ausencia de un tratamiento efectivo o de una vacuna, todos los esfuerzos deben hacerse para procurar un buen control metabólico de los pacientes con diabetes mellitus con y sin COVID-19. Por lo anterior, se plantean en este artículo de reflexión, diferentes propuestas para el tratamiento de la diabetes mellitus en la unidad de cuidados intensivos, sin descartar la forma ambulatoria, en donde la telemedicina y otras tecnologías permitirán acortar la distancia y mantener las medidas de aislamiento preventivo. Mención de responsabilidad : Alejandro Román-González, Luis Antonio Rodríguez, Carlos Alfonso Builes-Barrera, Diva Cristina Castro, Carlos Esteban Builes-Montaño, Clara María Arango-Toro, Johnayro Gutiérrez-Restrepo, Juan David Gómez Referencia : Iatreia ; 34(2): 161-171, abr.-jun. 2021. DOI (Digital Object Identifier) : 10.17533/10.17533/udea.iatreia.93 Derechos de uso : CC BY-NC-SA En línea : https://revistas.udea.edu.co/index.php/iatreia/article/view/341746 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5768 Diabetes mellitus y COVID-19: fisiopatología y propuesta de tratamiento para el control glucémico en el tiempo de la pandemia = Diabetes mellitus and COVID-19: pathophysiology and treatment proposal for glycemic control at the time of the pandemic [documento electrónico] / Carlos Esteban Builes Montaño, ; Clara María Arango Toro, . - 2021.
Obra : Iatreia
Idioma : Español (spa)
Palabras clave : Coronavirus COVID-19 Diabetes Mellitus Glucosa Sanguínea Virus del SRAS Resumen : El coronavirus 2 del síndrome respiratorio agudo grave es el tercer betacoronavirus desde el año 2003 capaz de ocasionar una infección del tracto respiratorio inferior, llevando, en casos críticos, al síndrome de dificultad respiratoria aguda y la muerte. La edad avanzada, la hipertensión arterial y la diabetes mellitus son, entre otros, tres factores determinantes en los peores desenlaces clínicos. Múltiples mecanismos pueden explicar la mayor susceptibilidad de las personas diabéticas a las infecciones respiratorias. La hiperglucemia crónica altera tanto a la inmunidad humoral como al celular. Esta enfermedad predispone a la sobreexpresión de la proteína de la membrana celular que sirve como receptora del virus y a una respuesta inflamatoria exacerbada, aumentando el riesgo de una descompensación y de la aparición de crisis hiperglicémicas. Ante la ausencia de un tratamiento efectivo o de una vacuna, todos los esfuerzos deben hacerse para procurar un buen control metabólico de los pacientes con diabetes mellitus con y sin COVID-19. Por lo anterior, se plantean en este artículo de reflexión, diferentes propuestas para el tratamiento de la diabetes mellitus en la unidad de cuidados intensivos, sin descartar la forma ambulatoria, en donde la telemedicina y otras tecnologías permitirán acortar la distancia y mantener las medidas de aislamiento preventivo. Mención de responsabilidad : Alejandro Román-González, Luis Antonio Rodríguez, Carlos Alfonso Builes-Barrera, Diva Cristina Castro, Carlos Esteban Builes-Montaño, Clara María Arango-Toro, Johnayro Gutiérrez-Restrepo, Juan David Gómez Referencia : Iatreia ; 34(2): 161-171, abr.-jun. 2021. DOI (Digital Object Identifier) : 10.17533/10.17533/udea.iatreia.93 Derechos de uso : CC BY-NC-SA En línea : https://revistas.udea.edu.co/index.php/iatreia/article/view/341746 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5768 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001693 AC-2021-018 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2021-018Adobe Acrobat PDF Hemolysis in Hemodialysis, Secondary to Severe Vena Cava Stenosis / Dahyana Cadavid Aljure ; Sergio Álvarez Vallejo ; Gloria María Posada Álvarez ; Eliana María Ruiz Aguilar ; Lina Marcela Higuita Urrego ; Catalina María Guerra Álvarez ; Sandra Marcela Marín Durango ; Catalina Ocampo Kohn ; John Fredy Nieto Ríos ; Arbey Aristizabal Álzate ; Gustavo Adolfo Zuluaga Valencia
Título : Hemolysis in Hemodialysis, Secondary to Severe Vena Cava Stenosis Tipo de documento : documento electrónico Autores : Dahyana Cadavid Aljure, ; Sergio Álvarez Vallejo, ; Gloria María Posada Álvarez, ; Eliana María Ruiz Aguilar, ; Lina Marcela Higuita Urrego, ; Catalina María Guerra Álvarez, ; Sandra Marcela Marín Durango, ; Catalina Ocampo Kohn, ; John Fredy Nieto Ríos, ; Arbey Aristizabal Álzate, ; Gustavo Adolfo Zuluaga Valencia, Fecha de publicación : 2021 Títulos uniformes : Cureus Idioma : Inglés (eng) Palabras clave : hemolysis anemia hemodialysis access stenosis blood circulation complications Resumen : Complications in hemodialysis patients are increasingly rare thanks to advances in technology, including more compatible membranes, more flexible lines, safety in water treatments, alarms in the circuit, and standardization in dialysate fluids plus exhaustive chemical and microbiological tests. In addition, it is highly unusual having hemolysis on hemodialysis; however, it is a life-threatening complication, so the cause must be identified and early managed. The etiology can be chemical or mechanical; however, so far, there are no reports in the literature of an association with severe stenosis of the vena cava, as it is described in the case reported here, where a patient presented hemolysis in two hemodialysis sessions, without initially being possible to find the cause; the only identifiable factor was that he had a dysfunctional tunneled jugular catheter, with a history of difficult vascular access. The patient underwent interventional radiology, finding 99% stenosis of the vena cava, which prevented the passage of the contrast agent to the atrium. Angioplasty and catheter replacement were performed, with a resolution of the complication; the subsequent dialysis therapies were satisfactory. Mención de responsabilidad : Dahyana Cadavid Aljure, Sergio Alvarez-Vallejo, Gloria Posada-Alvarez, Eliana Ruiz-Aguilar, Lina Higuita-Urrego, Catalina Guerra-Alvarez, Sandra Marin-Durango, Catalina Ocampo-Kohn, John Fredy Nieto-Rios, Arbey Aristizabal-Alzate, Gustavo Zuluaga-Valencia Referencia : Cureus. 2021 May 21;13(5):e15156. DOI (Digital Object Identifier) : 10.7759/cureus.15156 PMID : 34168923 En línea : https://www.cureus.com/articles/58087-hemolysis-in-hemodialysis-secondary-to-sev [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5800 Hemolysis in Hemodialysis, Secondary to Severe Vena Cava Stenosis [documento electrónico] / Dahyana Cadavid Aljure, ; Sergio Álvarez Vallejo, ; Gloria María Posada Álvarez, ; Eliana María Ruiz Aguilar, ; Lina Marcela Higuita Urrego, ; Catalina María Guerra Álvarez, ; Sandra Marcela Marín Durango, ; Catalina Ocampo Kohn, ; John Fredy Nieto Ríos, ; Arbey Aristizabal Álzate, ; Gustavo Adolfo Zuluaga Valencia, . - 2021.
Obra : Cureus
Idioma : Inglés (eng)
Palabras clave : hemolysis anemia hemodialysis access stenosis blood circulation complications Resumen : Complications in hemodialysis patients are increasingly rare thanks to advances in technology, including more compatible membranes, more flexible lines, safety in water treatments, alarms in the circuit, and standardization in dialysate fluids plus exhaustive chemical and microbiological tests. In addition, it is highly unusual having hemolysis on hemodialysis; however, it is a life-threatening complication, so the cause must be identified and early managed. The etiology can be chemical or mechanical; however, so far, there are no reports in the literature of an association with severe stenosis of the vena cava, as it is described in the case reported here, where a patient presented hemolysis in two hemodialysis sessions, without initially being possible to find the cause; the only identifiable factor was that he had a dysfunctional tunneled jugular catheter, with a history of difficult vascular access. The patient underwent interventional radiology, finding 99% stenosis of the vena cava, which prevented the passage of the contrast agent to the atrium. Angioplasty and catheter replacement were performed, with a resolution of the complication; the subsequent dialysis therapies were satisfactory. Mención de responsabilidad : Dahyana Cadavid Aljure, Sergio Alvarez-Vallejo, Gloria Posada-Alvarez, Eliana Ruiz-Aguilar, Lina Higuita-Urrego, Catalina Guerra-Alvarez, Sandra Marin-Durango, Catalina Ocampo-Kohn, John Fredy Nieto-Rios, Arbey Aristizabal-Alzate, Gustavo Zuluaga-Valencia Referencia : Cureus. 2021 May 21;13(5):e15156. DOI (Digital Object Identifier) : 10.7759/cureus.15156 PMID : 34168923 En línea : https://www.cureus.com/articles/58087-hemolysis-in-hemodialysis-secondary-to-sev [...] Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5800 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001731 AC-2021-050 Archivo digital Producción Científica Artículos científicos Disponible Tratamiento citorreductor disponible en Colombia para la trombocitemia esencial. Revisión panorámica de la evidencia / Kenny Mauricio Gálvez Cárdenas
Título : Tratamiento citorreductor disponible en Colombia para la trombocitemia esencial. Revisión panorámica de la evidencia Otros títulos : Cytoreductive treatment for essential thrombocythemia in Colombia. Panoramic review of the evidence Tipo de documento : documento electrónico Autores : Kenny Mauricio Gálvez Cárdenas, Fecha de publicación : 2021 Títulos uniformes : Revista Colombiana de Hematología y Oncología Idioma : Español (spa) Palabras clave : Trombocitemia esencial trastornos mieloproliferativos tratamiento farmacológico trombosis Resumen : La trombocitemia esencial (TE) es una neoplasia mieloproliferativa crónica BCR-ABL negativa, caracterizada por la producción excesiva de plaquetas clonales. La prevalencia mundial varía, siendo aproximadamente 38 a 57 por 100.000. El tratamiento de la TE tiene como objetivo reducir el riesgo de trombosis o complicaciones hemorrágicas. Objetivo: el objetivo de la presente revisión panorámica es evaluar la evidencia actual sobre el tratamiento citoreductor de la trombocitemia esencial disponible en Colombia. Métodos: se realizó una búsqueda estructurada de literatura respecto a la efectividad y seguridad de los tratamientos citoreductores en el paciente con trombocitemia esencial. A partir de la pregunta de investigación con estructura PICO, se definieron los criterios de inclusión: pacientes con trombocitemia esencial, en manejo con Anagrelida y/o Hidroxiurea. Se incluyeron estudios de revisiones sistemáticas, metanálisis, ensayos clínicos aleatorizados. Resultados: se realizó una búsqueda en MEDLINE, EMBASE, LILACS, Cochrane Database of systematic Reviews, que arrojó 119 referencias de las cuales se incluyeron cuatro estudios, que cumplían con las características de la población, intervención y comparador. Conclusiones: la terapia citorreductora es fundamental para el manejo de la trombocitemia esencial. La evidencia sugiere que tanto Hidroxiurea como Anangrelida son agentes que brindan una protección similar contra eventos trombo-hemorrágicos clínicamente significativos. Mención de responsabilidad : Virginia Abello Polo MD, Carmen Rosales Oliveros MD, Kenny Mauricio Gálvez Cárdenas MD, José Domingo Saavedra, Juan Guillermo Duque Ortega DOI (Digital Object Identifier) : 10.51643/22562915.335 Derechos de uso : CC BY-NC-ND En línea : https://revista.acho.info/index.php/acho/article/view/335 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5832 Tratamiento citorreductor disponible en Colombia para la trombocitemia esencial. Revisión panorámica de la evidencia = Cytoreductive treatment for essential thrombocythemia in Colombia. Panoramic review of the evidence [documento electrónico] / Kenny Mauricio Gálvez Cárdenas, . - 2021.
Obra : Revista Colombiana de Hematología y Oncología
Idioma : Español (spa)
Palabras clave : Trombocitemia esencial trastornos mieloproliferativos tratamiento farmacológico trombosis Resumen : La trombocitemia esencial (TE) es una neoplasia mieloproliferativa crónica BCR-ABL negativa, caracterizada por la producción excesiva de plaquetas clonales. La prevalencia mundial varía, siendo aproximadamente 38 a 57 por 100.000. El tratamiento de la TE tiene como objetivo reducir el riesgo de trombosis o complicaciones hemorrágicas. Objetivo: el objetivo de la presente revisión panorámica es evaluar la evidencia actual sobre el tratamiento citoreductor de la trombocitemia esencial disponible en Colombia. Métodos: se realizó una búsqueda estructurada de literatura respecto a la efectividad y seguridad de los tratamientos citoreductores en el paciente con trombocitemia esencial. A partir de la pregunta de investigación con estructura PICO, se definieron los criterios de inclusión: pacientes con trombocitemia esencial, en manejo con Anagrelida y/o Hidroxiurea. Se incluyeron estudios de revisiones sistemáticas, metanálisis, ensayos clínicos aleatorizados. Resultados: se realizó una búsqueda en MEDLINE, EMBASE, LILACS, Cochrane Database of systematic Reviews, que arrojó 119 referencias de las cuales se incluyeron cuatro estudios, que cumplían con las características de la población, intervención y comparador. Conclusiones: la terapia citorreductora es fundamental para el manejo de la trombocitemia esencial. La evidencia sugiere que tanto Hidroxiurea como Anangrelida son agentes que brindan una protección similar contra eventos trombo-hemorrágicos clínicamente significativos. Mención de responsabilidad : Virginia Abello Polo MD, Carmen Rosales Oliveros MD, Kenny Mauricio Gálvez Cárdenas MD, José Domingo Saavedra, Juan Guillermo Duque Ortega DOI (Digital Object Identifier) : 10.51643/22562915.335 Derechos de uso : CC BY-NC-ND En línea : https://revista.acho.info/index.php/acho/article/view/335 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5832 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001766 AC-2021-082 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2021-082Adobe Acrobat PDF Determinación de los niveles de cortisol salival en niños escolares y adolescentes sanos / Verónica Abad Londoño
Título : Determinación de los niveles de cortisol salival en niños escolares y adolescentes sanos Otros títulos : Determination of salival cortisol levels in healthy schoolchildren and adolescents Tipo de documento : documento electrónico Autores : Verónica Abad Londoño, Fecha de publicación : 2021 Títulos uniformes : Revista Colombiana de Endocrinología Diabetes y Metabolismo Idioma : Español (spa) Palabras clave : cortisol en saliva hipercortisolismo síndrome Cushing insuficiencia adrenal glucocorticoides Resumen : Objective: To determine salivary cortisol values in a small group of healthy schoolchildren and adolescents between the ages of 6-18 in the city of Medellín and determine their relationship with the circadian cycle according to the time of sampling. Introduction: Salivary cortisol is an ultrafiltrate of plasma cortisol and reflects biologically active levels, this follows the circadian variation of serum cortisol, finding the highest levels in the morning and lower levels at midnight. Methods: A descriptive observational study was carried out in which healthy schoolchildren and adolescents between 6 and 18 years of age were included. Two samples of saliva were collected in each child, the first at 8:00 a.m. and the second at 23:00 a.m. on the same day. The samples were processed by enzymatic immunoassay (EIA-ELISA) in Abad laboratory of the city of Medellín. The statistical method of Kolmogorov-Smirnov and Shapiro-Wilk was used to determine normality. For the presentation of results, the measures of central tendency and dispersion were used according to the normality of the variable. Results: Data from 31 individuals were analyzed. 51.6 % of the population were men. The average age was 11.26 years (± 3.4) and the average BMI was 18.1 kg/m2 (± 2.8). With respect to cortisol levels, the cortisol level at 08:00 a.m. a median of 4.39 ng/ml was obtained (RIQ 2.76-6.98); and for the cortisol level at 11:00 p.m., a median of 0.51 ng/ml (RIQ 0.41-0.84) was obtained. There were no significant differences by sex. Conclusion: The average salivary cortisol values in the group of healthy schoolchildren and adolescents in the city of Medellín are within the reference values reported in international studies, so it is recommended for the diagnosis and monitoring of hyper / hypocortisolism. Mención de responsabilidad : Vanessa Garzón Ruiz, Clemencia Pérez Betancur, Verónica Abad Londoño DOI (Digital Object Identifier) : 10.53853/encr.8.2.711 Derechos de uso : CC BY-NC-ND En línea : http://revistaendocrino.org/index.php/rcedm/article/view/711 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5896 Determinación de los niveles de cortisol salival en niños escolares y adolescentes sanos = Determination of salival cortisol levels in healthy schoolchildren and adolescents [documento electrónico] / Verónica Abad Londoño, . - 2021.
Obra : Revista Colombiana de Endocrinología Diabetes y Metabolismo
Idioma : Español (spa)
Palabras clave : cortisol en saliva hipercortisolismo síndrome Cushing insuficiencia adrenal glucocorticoides Resumen : Objective: To determine salivary cortisol values in a small group of healthy schoolchildren and adolescents between the ages of 6-18 in the city of Medellín and determine their relationship with the circadian cycle according to the time of sampling. Introduction: Salivary cortisol is an ultrafiltrate of plasma cortisol and reflects biologically active levels, this follows the circadian variation of serum cortisol, finding the highest levels in the morning and lower levels at midnight. Methods: A descriptive observational study was carried out in which healthy schoolchildren and adolescents between 6 and 18 years of age were included. Two samples of saliva were collected in each child, the first at 8:00 a.m. and the second at 23:00 a.m. on the same day. The samples were processed by enzymatic immunoassay (EIA-ELISA) in Abad laboratory of the city of Medellín. The statistical method of Kolmogorov-Smirnov and Shapiro-Wilk was used to determine normality. For the presentation of results, the measures of central tendency and dispersion were used according to the normality of the variable. Results: Data from 31 individuals were analyzed. 51.6 % of the population were men. The average age was 11.26 years (± 3.4) and the average BMI was 18.1 kg/m2 (± 2.8). With respect to cortisol levels, the cortisol level at 08:00 a.m. a median of 4.39 ng/ml was obtained (RIQ 2.76-6.98); and for the cortisol level at 11:00 p.m., a median of 0.51 ng/ml (RIQ 0.41-0.84) was obtained. There were no significant differences by sex. Conclusion: The average salivary cortisol values in the group of healthy schoolchildren and adolescents in the city of Medellín are within the reference values reported in international studies, so it is recommended for the diagnosis and monitoring of hyper / hypocortisolism. Mención de responsabilidad : Vanessa Garzón Ruiz, Clemencia Pérez Betancur, Verónica Abad Londoño DOI (Digital Object Identifier) : 10.53853/encr.8.2.711 Derechos de uso : CC BY-NC-ND En línea : http://revistaendocrino.org/index.php/rcedm/article/view/711 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5896 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001851 AC-2021-147 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2021-147Adobe Acrobat PDF Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson's Disease / Leonardo Fabio Moreno Gómez
Título : Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson's Disease Tipo de documento : documento electrónico Autores : Leonardo Fabio Moreno Gómez, Fecha de publicación : 2021 Títulos uniformes : Clinical Neurophysiology Idioma : Inglés (eng) Palabras clave : Alpha rhythm Electroencephalography Neuropsychological tests Parkinson’s Disease Theta rhythm Resumen : Objective: To determine possible associations of hemispheric-regional alpha/theta ratio (α/θ) with neuropsychological test performance in Parkinson's Disease (PD) non-demented patients. Methods: 36 PD were matched to 36 Healthy Controls (HC). The α/θ in eight hemispheric regions was computed from the relative power spectral density of the resting-state quantitative electroencephalogram (qEEG). Correlations between α/θ and performance in several neuropsychological tests were conducted, significant findings were included in a moderation analysis. Results: The α/θ in all regions was lower in PD than in HC, with larger effect sizes in the posterior regions. Right parietal, and right and left occipital α/θ had significant positive correlations with performance in Judgement of Line Orientation Test (JLOT) in PD. Adjusted moderation analysis indicated that right, but not left, occipital α/θ influenced the JLOT performance related to PD. Conclusions: Reduction of the occipital α/θ, in particular on the right side, was associated with visuospatial performance impairment in PD. Significance: Visuospatial impairment in PD, which is highly correlated with the subsequent development of dementia, is reflected in α/θ in the right posterior regions. The right occipital α/θ may represent a useful qEEG marker for evaluating the presence of early signs of cognitive decline in PD and the subsequent risk of dementia. Mención de responsabilidad : Alberto Jaramillo-Jimenez, Jazmin Ximena Suarez-Revelo, John Fredy Ochoa-Gomez, Jairo Alexander Carmona Arroyave, Yamile Bocanegra, Francisco Lopera, Omar Buriticá, David Antonio Pineda-Salazar, Leonardo Moreno Gómez, Carlos Andrés Tobón Quintero, Miguel Germán Borda, Laura Bonanni, Dominic H Ffytche, Kolbjørn Brønnick, Dag Aarsland Referencia : Clin Neurophysiol. 2021 Jan 13;132(3):756-764. DOI (Digital Object Identifier) : 10.1016/j.clinph.2021.01.001 PMID : 33571883 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1388-2457(21)00003-1 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5758 Resting-state EEG alpha/theta ratio related to neuropsychological test performance in Parkinson's Disease [documento electrónico] / Leonardo Fabio Moreno Gómez, . - 2021.
Obra : Clinical Neurophysiology
Idioma : Inglés (eng)
Palabras clave : Alpha rhythm Electroencephalography Neuropsychological tests Parkinson’s Disease Theta rhythm Resumen : Objective: To determine possible associations of hemispheric-regional alpha/theta ratio (α/θ) with neuropsychological test performance in Parkinson's Disease (PD) non-demented patients. Methods: 36 PD were matched to 36 Healthy Controls (HC). The α/θ in eight hemispheric regions was computed from the relative power spectral density of the resting-state quantitative electroencephalogram (qEEG). Correlations between α/θ and performance in several neuropsychological tests were conducted, significant findings were included in a moderation analysis. Results: The α/θ in all regions was lower in PD than in HC, with larger effect sizes in the posterior regions. Right parietal, and right and left occipital α/θ had significant positive correlations with performance in Judgement of Line Orientation Test (JLOT) in PD. Adjusted moderation analysis indicated that right, but not left, occipital α/θ influenced the JLOT performance related to PD. Conclusions: Reduction of the occipital α/θ, in particular on the right side, was associated with visuospatial performance impairment in PD. Significance: Visuospatial impairment in PD, which is highly correlated with the subsequent development of dementia, is reflected in α/θ in the right posterior regions. The right occipital α/θ may represent a useful qEEG marker for evaluating the presence of early signs of cognitive decline in PD and the subsequent risk of dementia. Mención de responsabilidad : Alberto Jaramillo-Jimenez, Jazmin Ximena Suarez-Revelo, John Fredy Ochoa-Gomez, Jairo Alexander Carmona Arroyave, Yamile Bocanegra, Francisco Lopera, Omar Buriticá, David Antonio Pineda-Salazar, Leonardo Moreno Gómez, Carlos Andrés Tobón Quintero, Miguel Germán Borda, Laura Bonanni, Dominic H Ffytche, Kolbjørn Brønnick, Dag Aarsland Referencia : Clin Neurophysiol. 2021 Jan 13;132(3):756-764. DOI (Digital Object Identifier) : 10.1016/j.clinph.2021.01.001 PMID : 33571883 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1388-2457(21)00003-1 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5758 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001678 AC-2021-009 Archivo digital Producción Científica Artículos científicos Disponible Impact of COVID-19 infection on patients with cancer: experience in a Latin American country: the ACHOCC-19 study / Alicia Quiroga Echeverri
Título : Impact of COVID-19 infection on patients with cancer: experience in a Latin American country: the ACHOCC-19 study Tipo de documento : documento electrónico Autores : Alicia Quiroga Echeverri, Fecha de publicación : 2021 Títulos uniformes : The Oncologist Idioma : Inglés (eng) Palabras clave : Cancer Covid-19 Latin America mortality survival Resumen : Introduction: The ACHOCC-19 study was performed to characterize COVID-19 infection in our oncological population. Methodology: Analytical cohort study of patients with cancer and COVID-19 infection in Colombia. From April 1 to October 31, 2020. Demographic and clinical variables related to cancer and COVID-19 infection were collected. The primary outcome was 30-day mortality from all causes. The association between the outcome and the prognostic variables was analyzed using logistic regression models and survival analysis with Cox regression. Results: 742 patients were included. 72% > 51 years. The most prevalent neoplasms were breast (132 [17,77%]), colorectal (92 12,34%), and prostate (81 [10,9%]). 220 (29,6%) patients were asymptomatic and 96 (26,3%) died. In the bivariate descriptive analysis, higher mortality in patients > 70 years, lung cancer, ≥2 comorbidities, former smokers, receiving antibiotics, corticosteroids, and anticoagulants, residents of rural areas, low socioeconomic status, and increased acute phase reactants. In the logistic regression analysis, higher mortality with ECOG 3 OR 28,67 (8,2-99,6), ECOG 4 OR 20,89 (3,36-129,7), two complications from COVID-19 OR 5,3 (1,50-18,1), and cancer in progression OR 02,08 (1,01-4,27). In the Cox regression analysis, the statistically significant HRs were metastatic disease HR 1,58 (1,16 - 2,16), cancer in progression HR 1,08 (1,24 - 2,61) vs partial response HR 0,31 (0,11 - 0,88), use of steroids HR 1,44 (1,01 - 2,06) and antibiotics HR 2,11 (1,47 - 2,95). Interpretations: In our study, cancer patients have higher mortality due to COVID-19 infection if they have active cancer, metastatic or progressive cancer, ECOG status >2 and low socioeconomic status. Implications for practice: Our findings raise the need to carefully evaluate patients with metastatic cancer, in progression, and with impaired ECOG to define the relevance of cancer treatment during the pandemic, consider the risk/benefit of the interventions, and establish clear and complete communication with the patients and their families about the risk of complications. There is also the importance of offering additional support to patients with low income and residence in rural areas so that they can have more support during cancer treatment. Mención de responsabilidad : Aylen Vanessa Ospina, Ricardo Bruges, William Mantilla, Iván Triana, Pedro Ramos, Sandra Aruachan, Alicia Quiroga, Isabel Munevar, Juan Ortiz, Néstor Llinás, Paola Pinilla, Henry Vargas, Henry Idrobo, Andrea Russi, Ray Manneh Kopp, Giovanna Rivas, Héctor González, Daniel Santa, Jesús Insuasty, Laura Bernal, Jorge Otero, Carlos Vargas, Javier Pacheco, Carmen Alcalá, Paola Jiménez, Milton Lombana, Fernando Contreras, Javier Segovia, Luis Pino, José Lobatón, Manuel González, Javier Cuello, Juliana Bogoya, Angela Barrero, Gilberto de Lima Lopes Jr Referencia : Oncologist. 2021 Oct;26(10):e1761-e1773. DOI (Digital Object Identifier) : 10.1002/onco.13861 PMID : 34132449 En línea : https://theoncologist.onlinelibrary.wiley.com/doi/10.1002/onco.13861 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5791 Impact of COVID-19 infection on patients with cancer: experience in a Latin American country: the ACHOCC-19 study [documento electrónico] / Alicia Quiroga Echeverri, . - 2021.
Obra : The Oncologist
Idioma : Inglés (eng)
Palabras clave : Cancer Covid-19 Latin America mortality survival Resumen : Introduction: The ACHOCC-19 study was performed to characterize COVID-19 infection in our oncological population. Methodology: Analytical cohort study of patients with cancer and COVID-19 infection in Colombia. From April 1 to October 31, 2020. Demographic and clinical variables related to cancer and COVID-19 infection were collected. The primary outcome was 30-day mortality from all causes. The association between the outcome and the prognostic variables was analyzed using logistic regression models and survival analysis with Cox regression. Results: 742 patients were included. 72% > 51 years. The most prevalent neoplasms were breast (132 [17,77%]), colorectal (92 12,34%), and prostate (81 [10,9%]). 220 (29,6%) patients were asymptomatic and 96 (26,3%) died. In the bivariate descriptive analysis, higher mortality in patients > 70 years, lung cancer, ≥2 comorbidities, former smokers, receiving antibiotics, corticosteroids, and anticoagulants, residents of rural areas, low socioeconomic status, and increased acute phase reactants. In the logistic regression analysis, higher mortality with ECOG 3 OR 28,67 (8,2-99,6), ECOG 4 OR 20,89 (3,36-129,7), two complications from COVID-19 OR 5,3 (1,50-18,1), and cancer in progression OR 02,08 (1,01-4,27). In the Cox regression analysis, the statistically significant HRs were metastatic disease HR 1,58 (1,16 - 2,16), cancer in progression HR 1,08 (1,24 - 2,61) vs partial response HR 0,31 (0,11 - 0,88), use of steroids HR 1,44 (1,01 - 2,06) and antibiotics HR 2,11 (1,47 - 2,95). Interpretations: In our study, cancer patients have higher mortality due to COVID-19 infection if they have active cancer, metastatic or progressive cancer, ECOG status >2 and low socioeconomic status. Implications for practice: Our findings raise the need to carefully evaluate patients with metastatic cancer, in progression, and with impaired ECOG to define the relevance of cancer treatment during the pandemic, consider the risk/benefit of the interventions, and establish clear and complete communication with the patients and their families about the risk of complications. There is also the importance of offering additional support to patients with low income and residence in rural areas so that they can have more support during cancer treatment. Mención de responsabilidad : Aylen Vanessa Ospina, Ricardo Bruges, William Mantilla, Iván Triana, Pedro Ramos, Sandra Aruachan, Alicia Quiroga, Isabel Munevar, Juan Ortiz, Néstor Llinás, Paola Pinilla, Henry Vargas, Henry Idrobo, Andrea Russi, Ray Manneh Kopp, Giovanna Rivas, Héctor González, Daniel Santa, Jesús Insuasty, Laura Bernal, Jorge Otero, Carlos Vargas, Javier Pacheco, Carmen Alcalá, Paola Jiménez, Milton Lombana, Fernando Contreras, Javier Segovia, Luis Pino, José Lobatón, Manuel González, Javier Cuello, Juliana Bogoya, Angela Barrero, Gilberto de Lima Lopes Jr Referencia : Oncologist. 2021 Oct;26(10):e1761-e1773. DOI (Digital Object Identifier) : 10.1002/onco.13861 PMID : 34132449 En línea : https://theoncologist.onlinelibrary.wiley.com/doi/10.1002/onco.13861 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5791 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001722 AC-2021-041 Archivo digital Producción Científica Artículos científicos Disponible Contribución del químico farmacéutico en los programas de gerenciamiento de antimicrobianos: estudio de cohortes ambispectivo / Elkyn Johan Granados Vega
Título : Contribución del químico farmacéutico en los programas de gerenciamiento de antimicrobianos: estudio de cohortes ambispectivo Otros títulos : Pharmacist's contribution on antimicrobial stewardship program: ambispective cohort study Tipo de documento : documento electrónico Autores : Elkyn Johan Granados Vega, Fecha de publicación : 2021 Títulos uniformes : Revista Chilena de Infectología Idioma : Español (spa) Palabras clave : programa de gerenciamiento de antimicrobianos químico farmacéutico resistencia bacteriana servicio farmacia hospitalaria atención farmacéutica Resumen : Introducción: El programa de gerenciamiento de antimicrobianos (PGAn) promueve el uso racional de los antimicrobianos, garantizando que cada paciente reciba el fármaco correcto, por el tiempo correcto, por la vía y a la dosis correcta. Objetivo: Establecer la asociación de los resultados de un PGAn liderado por un químico farmacéutico, en términos de consumo de antimicrobianos, duración del tratamiento y costos, en una institución prestadora de salud de alta complejidad. Materiales y Método: Estudio de cohortes ambispectivo. En la cohorte expuesta, (entorno de un PGAn), un químico farmacéutico con entrenamiento en enfermedades infecciosas evaluó e intervino la indicación, dosis, duración del tratamiento y espectro bacteriano del antimicrobiano. La cohorte no expuesta fue una población retrospectiva similar (pareada) a la cohorte expuesta, pero sin la evaluación de su terapia antimicrobiana. Resultados: Se identificaron 258 pacientes en la cohorte expuesta y 247 en la cohorte no expuesta al PGAn. Se observó una disminución en el consumo de antimicrobianos (119.831 vs 137.678 DDD/100 pacientes-día, p Mención de responsabilidad : Héctor Holguín, Pedro Amariles, William Ospina, Miguel Pinzón, Johan Granados Referencia : Rev Chilena Infectol. 2021 Aug;38(4):480-487. DOI (Digital Object Identifier) : 10.4067/S0716-10182021000400480 PMID : 34652392 Derechos de uso : CC BY-NC En línea : https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-10182021000400480 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5855 Contribución del químico farmacéutico en los programas de gerenciamiento de antimicrobianos: estudio de cohortes ambispectivo = Pharmacist's contribution on antimicrobial stewardship program: ambispective cohort study [documento electrónico] / Elkyn Johan Granados Vega, . - 2021.
Obra : Revista Chilena de Infectología
Idioma : Español (spa)
Palabras clave : programa de gerenciamiento de antimicrobianos químico farmacéutico resistencia bacteriana servicio farmacia hospitalaria atención farmacéutica Resumen : Introducción: El programa de gerenciamiento de antimicrobianos (PGAn) promueve el uso racional de los antimicrobianos, garantizando que cada paciente reciba el fármaco correcto, por el tiempo correcto, por la vía y a la dosis correcta. Objetivo: Establecer la asociación de los resultados de un PGAn liderado por un químico farmacéutico, en términos de consumo de antimicrobianos, duración del tratamiento y costos, en una institución prestadora de salud de alta complejidad. Materiales y Método: Estudio de cohortes ambispectivo. En la cohorte expuesta, (entorno de un PGAn), un químico farmacéutico con entrenamiento en enfermedades infecciosas evaluó e intervino la indicación, dosis, duración del tratamiento y espectro bacteriano del antimicrobiano. La cohorte no expuesta fue una población retrospectiva similar (pareada) a la cohorte expuesta, pero sin la evaluación de su terapia antimicrobiana. Resultados: Se identificaron 258 pacientes en la cohorte expuesta y 247 en la cohorte no expuesta al PGAn. Se observó una disminución en el consumo de antimicrobianos (119.831 vs 137.678 DDD/100 pacientes-día, p Mención de responsabilidad : Héctor Holguín, Pedro Amariles, William Ospina, Miguel Pinzón, Johan Granados Referencia : Rev Chilena Infectol. 2021 Aug;38(4):480-487. DOI (Digital Object Identifier) : 10.4067/S0716-10182021000400480 PMID : 34652392 Derechos de uso : CC BY-NC En línea : https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-10182021000400480 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5855 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001793 AC-2021-105 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2021-105Adobe Acrobat PDF Tromboprofilaxis, anticoagulación y coagulopatía en tiempos de pandemia: recomendación de la ACATA, ACMI, SCC CCV y ACMV / Kenny Mauricio Gálvez Cárdenas
Título : Tromboprofilaxis, anticoagulación y coagulopatía en tiempos de pandemia: recomendación de la ACATA, ACMI, SCC CCV y ACMV Otros títulos : Thromboprophylaxis, anticoagulation and coagulopathy in times of pandemic: The ACATA, ACMI, SCC CCV and ACMV recommendation Tipo de documento : documento electrónico Autores : Kenny Mauricio Gálvez Cárdenas, Fecha de publicación : 2021 Títulos uniformes : Revista Colombiana de Cardiología Idioma : Español (spa) Palabras clave : Tromboprofilaxis Anticoagulación Trombosis Anticoagulantes COVID-19 Coronavirus Resumen : Introducción: La enfermedad por coronavirus 2019 (COVID-19) puede predisponer a tromboembolia venosa o trombosis arterial debido a una respuesta inflamatoria aumentada, hipoxia, inmovilización y coagulación intravascular diseminada; hasta en un 20 a 50% de pacientes hospitalizados con COVID-19 tienen alteraciones hematológicas relacionadas con coagulopatía (dímero D elevado, tiempo de protrombina prolongado, trombocitopenia y/o fibrinógeno bajo). Evaluaciones post mortem evidencian depósitos trombóticos microvasculares típicos, ricos en plaquetas en vasos pequeños de pulmones y otros órganos. Objetivo: Brindar una aproximación práctica y actualizada en el manejo del paciente con riesgo elevado o que presentan eventos tromboembólicos en el marco de la actual pandemia por COVID-19. Material y métodos: Se realizó una revisión narrativa que incluyó estudios observacionales descriptivos. Se efectuó una búsqueda de la literatura de evidencia médica en diferentes buscadores como Science Direct y PubMed, usando las palabras claves “thromboprophylaxis”, “anticoagulation”, “thrombosis”, “anticoagulant”, “COVID-19”, “SARS-CoV-2”, “coronavirus”. Posteriormente se escribieron las recomendaciones generales referentes al tema. Conclusiones: Existen diferentes formas en las que la pandemia por COVID-19 puede predisponer al desarrollo de enfermedades trombóticas o tromboembólicas, el efecto directo o indirecto de este virus relacionado con la tormenta de citocinas que precipita el inicio del síndrome de respuesta inflamatoria sistémica y predispone al desarrollo de eventos trombóticos; también las intervenciones disponibles pueden tener interacciones farmacológicas con antiagregantes y/o anticoagulantes. Mención de responsabilidad : Juan E. Gómez-Mesa, Ana C. Montenegro, Kenny M. Gálvez, Dora I. Molina, Gilberto Amed-Castillo, Luis E. Echeverría, María-Claudia Montes, Stephania Galindo-Coral Referencia : Rev. colomb. cardiol ; 28(6): 539-547, nov.-dic. 2021. DOI (Digital Object Identifier) : 10.24875/RCCAR.M21000095 Derechos de uso : CC BY-NC-ND En línea : https://www.rccardiologia.com/frame_esp.php?id=108 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5887 Tromboprofilaxis, anticoagulación y coagulopatía en tiempos de pandemia: recomendación de la ACATA, ACMI, SCC CCV y ACMV = Thromboprophylaxis, anticoagulation and coagulopathy in times of pandemic: The ACATA, ACMI, SCC CCV and ACMV recommendation [documento electrónico] / Kenny Mauricio Gálvez Cárdenas, . - 2021.
Obra : Revista Colombiana de Cardiología
Idioma : Español (spa)
Palabras clave : Tromboprofilaxis Anticoagulación Trombosis Anticoagulantes COVID-19 Coronavirus Resumen : Introducción: La enfermedad por coronavirus 2019 (COVID-19) puede predisponer a tromboembolia venosa o trombosis arterial debido a una respuesta inflamatoria aumentada, hipoxia, inmovilización y coagulación intravascular diseminada; hasta en un 20 a 50% de pacientes hospitalizados con COVID-19 tienen alteraciones hematológicas relacionadas con coagulopatía (dímero D elevado, tiempo de protrombina prolongado, trombocitopenia y/o fibrinógeno bajo). Evaluaciones post mortem evidencian depósitos trombóticos microvasculares típicos, ricos en plaquetas en vasos pequeños de pulmones y otros órganos. Objetivo: Brindar una aproximación práctica y actualizada en el manejo del paciente con riesgo elevado o que presentan eventos tromboembólicos en el marco de la actual pandemia por COVID-19. Material y métodos: Se realizó una revisión narrativa que incluyó estudios observacionales descriptivos. Se efectuó una búsqueda de la literatura de evidencia médica en diferentes buscadores como Science Direct y PubMed, usando las palabras claves “thromboprophylaxis”, “anticoagulation”, “thrombosis”, “anticoagulant”, “COVID-19”, “SARS-CoV-2”, “coronavirus”. Posteriormente se escribieron las recomendaciones generales referentes al tema. Conclusiones: Existen diferentes formas en las que la pandemia por COVID-19 puede predisponer al desarrollo de enfermedades trombóticas o tromboembólicas, el efecto directo o indirecto de este virus relacionado con la tormenta de citocinas que precipita el inicio del síndrome de respuesta inflamatoria sistémica y predispone al desarrollo de eventos trombóticos; también las intervenciones disponibles pueden tener interacciones farmacológicas con antiagregantes y/o anticoagulantes. Mención de responsabilidad : Juan E. Gómez-Mesa, Ana C. Montenegro, Kenny M. Gálvez, Dora I. Molina, Gilberto Amed-Castillo, Luis E. Echeverría, María-Claudia Montes, Stephania Galindo-Coral Referencia : Rev. colomb. cardiol ; 28(6): 539-547, nov.-dic. 2021. DOI (Digital Object Identifier) : 10.24875/RCCAR.M21000095 Derechos de uso : CC BY-NC-ND En línea : https://www.rccardiologia.com/frame_esp.php?id=108 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5887 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001828 AC-2021-137 Archivo digital Producción Científica Artículos científicos Disponible Documentos electrónicos
2021-137Adobe Acrobat PDF
Título : Harvesting the anterolateral thigh flap with non-sizable perforators Tipo de documento : documento electrónico Autores : Alejandro Zapata Ospina, Fecha de publicación : 2021 Títulos uniformes : Journal of Plastic, Reconstructive & Aesthetic Surgery Idioma : Inglés (eng) Palabras clave : anterolateral thigh flap non-sizable perforator myocutaneous flap capillary perforator Resumen : Background: The anterolateral thigh flap (ALT) has proven over time to be one of the best reconstructive workhorse thanks to its versatility and reliability. Without preoperative imaging, vascular anomalies such as having no sizable perforator are sometimes encountered during dissection. We propose a technique, based on a modified version of the traditional myocutaneous ALT to allow harvest of the flap based on non-sizable perforators. This technique can also enable splitting of a flap when only one sizable perforator is present. Methods: A retrospective review was done of patients who received reconstruction with free ALT flap from 2013 to 2019 by the senior author HSS and included all flaps in which non-sizable perforators were harvested. Data collected for analysis included patient demographics, flap size, defect location, inset type and flap survival. Surgical Technique: Despite detachment of the majority of skin paddle from the muscle, the flap is harvested with a sleeve of areolar tissue containing preferably more than one non-sizable perforators attached to a small muscular segment of the vastus lateralis containing the pedicle. Results: A total of 349 ALT flaps were performed during the review period by senior author HSS, and 25 flaps were harvested with non-sizable perforator, 10 of which were to enable a split. There were no total losses and 6 partial losses; 2 were amenable to direct closure after debridement, 1 required skin graft, and 3 required a new flap for wound coverage. Incorporating more than one non-sizable perforator increases the reliability of the flap. This technique should be used with caution in patients with multiple underlying comorbidities and when a flow-through flap is required. We were able to achieve primary closure of all donor sites. Conclusions: It is possible to harvest the anterolateral thigh flap without sizable perforators by conversion to a modified version of myocutaneous flap. In well selected patients, using our technique, several non-sizable perforators can reliably perfuse an ALT without the need to use an alternative donor site. This maximizes the number of harvestable ALTs and also increases the reconstructive potential by splitting previously “un-splitable” flaps. Mención de responsabilidad : Alejandro Zapata-Ospina, Jill Chen, Richard Tee, Seng-Feng Jeng, Bishal Karki y Hsiang-Shun Shih Referencia : J Plast Reconstr Aesthet Surg. 2021 May;74(5):1022-1030. DOI (Digital Object Identifier) : 10.1016/j.bjps.2020.10.063 PMID : 33551361 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1748681520305611 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5195 Harvesting the anterolateral thigh flap with non-sizable perforators [documento electrónico] / Alejandro Zapata Ospina, . - 2021.
Obra : Journal of Plastic, Reconstructive & Aesthetic Surgery
Idioma : Inglés (eng)
Palabras clave : anterolateral thigh flap non-sizable perforator myocutaneous flap capillary perforator Resumen : Background: The anterolateral thigh flap (ALT) has proven over time to be one of the best reconstructive workhorse thanks to its versatility and reliability. Without preoperative imaging, vascular anomalies such as having no sizable perforator are sometimes encountered during dissection. We propose a technique, based on a modified version of the traditional myocutaneous ALT to allow harvest of the flap based on non-sizable perforators. This technique can also enable splitting of a flap when only one sizable perforator is present. Methods: A retrospective review was done of patients who received reconstruction with free ALT flap from 2013 to 2019 by the senior author HSS and included all flaps in which non-sizable perforators were harvested. Data collected for analysis included patient demographics, flap size, defect location, inset type and flap survival. Surgical Technique: Despite detachment of the majority of skin paddle from the muscle, the flap is harvested with a sleeve of areolar tissue containing preferably more than one non-sizable perforators attached to a small muscular segment of the vastus lateralis containing the pedicle. Results: A total of 349 ALT flaps were performed during the review period by senior author HSS, and 25 flaps were harvested with non-sizable perforator, 10 of which were to enable a split. There were no total losses and 6 partial losses; 2 were amenable to direct closure after debridement, 1 required skin graft, and 3 required a new flap for wound coverage. Incorporating more than one non-sizable perforator increases the reliability of the flap. This technique should be used with caution in patients with multiple underlying comorbidities and when a flow-through flap is required. We were able to achieve primary closure of all donor sites. Conclusions: It is possible to harvest the anterolateral thigh flap without sizable perforators by conversion to a modified version of myocutaneous flap. In well selected patients, using our technique, several non-sizable perforators can reliably perfuse an ALT without the need to use an alternative donor site. This maximizes the number of harvestable ALTs and also increases the reconstructive potential by splitting previously “un-splitable” flaps. Mención de responsabilidad : Alejandro Zapata-Ospina, Jill Chen, Richard Tee, Seng-Feng Jeng, Bishal Karki y Hsiang-Shun Shih Referencia : J Plast Reconstr Aesthet Surg. 2021 May;74(5):1022-1030. DOI (Digital Object Identifier) : 10.1016/j.bjps.2020.10.063 PMID : 33551361 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1748681520305611 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5195 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001644 AC-2020-138 Archivo digital Producción Científica Artículos científicos Disponible Comparison of immediate colposcopy, repeat conventional cytology and high-risk human papillomavirus testing for the clinical management of atypical squamous cells of undetermined significance cytology in routine health services of Medellin, Colombia: The ASCUS-COL trial / Marcela Riveros Ángel
Título : Comparison of immediate colposcopy, repeat conventional cytology and high-risk human papillomavirus testing for the clinical management of atypical squamous cells of undetermined significance cytology in routine health services of Medellin, Colombia: The ASCUS-COL trial Tipo de documento : documento electrónico Autores : Marcela Riveros Ángel, Fecha de publicación : 2021 Títulos uniformes : International Journal of Cancer Idioma : Inglés (eng) Resumen : In the context of opportunistic cervical cancer screening settings of low-and-middle-income countries, little is known about the benefits of high-risk human papillomavirus (hrHPV) testing on high-grade cervical abnormality detection among women with atypical squamous cells of undetermined significance (ASC-US) cytology in routine clinical practice. We compared the effectiveness of immediate colposcopy (IC), conventional cytology at 6 and 12 months (colposcopy if ≥ASC-US) (RC) and hrHPV testing (colposcopy if hrHPV-positive) (HPV) to detect cervical intraepithelial neoplasia grade 2 or more severe diagnoses (CIN2+) among women aged 20 to 69 years with ASC-US in routine care. Participants (n = 2661) were evenly randomized into three arms (n = 882 IC, n = 890 RC, n = 889 HPV) to receive services by routine healthcare providers and invited to an exit visit 24 months after recruitment. Histopathology was blindly reviewed by a quality-control external panel (QC). The primary endpoint was the first QC-diagnosed CIN2+ or CIN3+ detected during three periods: enrolment (≤6 months for IC and HPV, ≤12 months for RC), follow-up (between enrolment and exit visit) and exit visit. The trial is completed. Colposcopy was done on 88%, 42% and 52% of participants in IC, RC and HPV. Overall, 212 CIN2+ and 52 CIN3+ cases were diagnosed. No differences were observed for CIN2+ detection (P = .821). However, compared to IC, only HPV significantly reduced CIN3+ cases that providers were unable to detect during the 2-year routine follow-up (relative proportion 0.35, 95% CI 0.09-0.87). In this context, hrHPV testing was the most effective and efficient management strategy for women with ASC-US cytology. Mención de responsabilidad : Armando Baena, Maria C. Agudelo, Carolina Lopez, Arianis Tatiana Ramírez, Kelly Melisa Castañeda, Astrid M. Bedoya, Marcela Riveros, Guadalupe Posada, Mauricio Borrero, Carlos A. Buitrago, David Suescun, Luis J. Gomez, Juan C. Ochoa, Mark Stoler, Julia Gage, Philip E. Castle, Peter Sasieni, Maribel Almonte, Rolando Herrero, Gloria I. Sanchez, for the ASCUS-COL Trial Group Referencia : Int J Cancer. 2020 Oct 2. DOI (Digital Object Identifier) : 10.1002/ijc.33318 PMID : 33006400 En línea : https://onlinelibrary.wiley.com/doi/10.1002/ijc.33318 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5749 Comparison of immediate colposcopy, repeat conventional cytology and high-risk human papillomavirus testing for the clinical management of atypical squamous cells of undetermined significance cytology in routine health services of Medellin, Colombia: The ASCUS-COL trial [documento electrónico] / Marcela Riveros Ángel, . - 2021.
Obra : International Journal of Cancer
Idioma : Inglés (eng)
Resumen : In the context of opportunistic cervical cancer screening settings of low-and-middle-income countries, little is known about the benefits of high-risk human papillomavirus (hrHPV) testing on high-grade cervical abnormality detection among women with atypical squamous cells of undetermined significance (ASC-US) cytology in routine clinical practice. We compared the effectiveness of immediate colposcopy (IC), conventional cytology at 6 and 12 months (colposcopy if ≥ASC-US) (RC) and hrHPV testing (colposcopy if hrHPV-positive) (HPV) to detect cervical intraepithelial neoplasia grade 2 or more severe diagnoses (CIN2+) among women aged 20 to 69 years with ASC-US in routine care. Participants (n = 2661) were evenly randomized into three arms (n = 882 IC, n = 890 RC, n = 889 HPV) to receive services by routine healthcare providers and invited to an exit visit 24 months after recruitment. Histopathology was blindly reviewed by a quality-control external panel (QC). The primary endpoint was the first QC-diagnosed CIN2+ or CIN3+ detected during three periods: enrolment (≤6 months for IC and HPV, ≤12 months for RC), follow-up (between enrolment and exit visit) and exit visit. The trial is completed. Colposcopy was done on 88%, 42% and 52% of participants in IC, RC and HPV. Overall, 212 CIN2+ and 52 CIN3+ cases were diagnosed. No differences were observed for CIN2+ detection (P = .821). However, compared to IC, only HPV significantly reduced CIN3+ cases that providers were unable to detect during the 2-year routine follow-up (relative proportion 0.35, 95% CI 0.09-0.87). In this context, hrHPV testing was the most effective and efficient management strategy for women with ASC-US cytology. Mención de responsabilidad : Armando Baena, Maria C. Agudelo, Carolina Lopez, Arianis Tatiana Ramírez, Kelly Melisa Castañeda, Astrid M. Bedoya, Marcela Riveros, Guadalupe Posada, Mauricio Borrero, Carlos A. Buitrago, David Suescun, Luis J. Gomez, Juan C. Ochoa, Mark Stoler, Julia Gage, Philip E. Castle, Peter Sasieni, Maribel Almonte, Rolando Herrero, Gloria I. Sanchez, for the ASCUS-COL Trial Group Referencia : Int J Cancer. 2020 Oct 2. DOI (Digital Object Identifier) : 10.1002/ijc.33318 PMID : 33006400 En línea : https://onlinelibrary.wiley.com/doi/10.1002/ijc.33318 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5749 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001822 AC-2020-159 Archivo digital Producción Científica Artículos científicos Disponible