Induced sputum as an adequate clinical specimen for the etiological diagnosis of community-acquired pneumonia (CAP) in children and adolescents / Andrea Victoria Restrepo Gouzy ; Mónica Rosa Trujillo Honeysberg    

Público ISBD Título : Induced sputum as an adequate clinical specimen for the etiological diagnosis of community-acquired pneumonia (CAP) in children and adolescents Tipo de documento : documento electrónico Autores : Andrea Victoria Restrepo Gouzy, ; Mónica Rosa Trujillo Honeysberg, Fecha de publicación : 2022 Títulos uniformes : International Journal of Infectious Diseases Idioma : Inglés (eng) Palabras clave : Induced sputum  adolescents  children  diagnosis  etiology  pneumonia Resumen : Objectives: This study aimed to evaluate the utility of induced sputum (IS) for the diagnosis of community-acquired pneumonia (CAP) in pediatric population. Methods: This cross-sectional study included pediatric population aged between 1 month and 17 years who were hospitalized with a diagnosis of CAP in 13 hospitals in Colombia, in whom an IS sample was obtained. Gram staining, aerobic bacterial and mycobacterial culture tests, and polymerase chain reaction (PCR) for 6 atypical bacteria and 15 respiratory viruses were performed. We evaluated the quality of IS samples. Results: IS samples were collected in 516 of 525 children included in this study. The median age was 32 months, 38.6% were younger than 2 years, and 40.9% were between 2 and 5 years. Two patients had transient hypoxemia during the procedure. The quality of the IS obtained was good in 48.4% and intermediate in 24.5%. Identification of a respiratory pathogen was achieved with an IS sample (with Gram staining, culture test, and PCR) in 372 of 516 children with CAP. Conclusion: Our study shows that IS is an adequate sample for the diagnosis of CAP in pediatric population that required hospitalization. The procedure was safe, well tolerated, and with better diagnostic yields compared with the rest of the samples obtained. Mención de responsabilidad : Zulma Vanessa Rueda, Marcela Bermúdez, Andrea Restrepo, Carlos Garcés, Olga Morales, Claudia Roya-Pabón, Luisa Fernanda Carmona, Catalina Arango, Jose Luis Albarracín, Lucelly López, Yudy Aguilar, María Angélica Maya, Mónica Trujillo, Ángela Rocio Copete, Cristian Vera, Mariana Herrera, Margarita Rosa Giraldo, Gloria Isabel Niño-Cruz, Lázaro A Vélez Referencia : Int J Infect Dis. 2022 Jan 19;116:348-354. DOI (Digital Object Identifier) : 10.1016/j.ijid.2022.01.026 PMID : 35063681 Derechos de uso : CC BY-NC-ND En línea : https://linkinghub.elsevier.com/retrieve/pii/S1201-9712(22)00025-X Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6010 Induced sputum as an adequate clinical specimen for the etiological diagnosis of community-acquired pneumonia (CAP) in children and adolescents [documento electrónico] / Andrea Victoria Restrepo Gouzy, ; Mónica Rosa Trujillo Honeysberg,  . - 2022. Obra : International Journal of Infectious Diseases Idioma : Inglés (eng) Palabras clave : Induced sputum  adolescents  children  diagnosis  etiology  pneumonia Resumen : Objectives: This study aimed to evaluate the utility of induced sputum (IS) for the diagnosis of community-acquired pneumonia (CAP) in pediatric population. Methods: This cross-sectional study included pediatric population aged between 1 month and 17 years who were hospitalized with a diagnosis of CAP in 13 hospitals in Colombia, in whom an IS sample was obtained. Gram staining, aerobic bacterial and mycobacterial culture tests, and polymerase chain reaction (PCR) for 6 atypical bacteria and 15 respiratory viruses were performed. We evaluated the quality of IS samples. Results: IS samples were collected in 516 of 525 children included in this study. The median age was 32 months, 38.6% were younger than 2 years, and 40.9% were between 2 and 5 years. Two patients had transient hypoxemia during the procedure. The quality of the IS obtained was good in 48.4% and intermediate in 24.5%. Identification of a respiratory pathogen was achieved with an IS sample (with Gram staining, culture test, and PCR) in 372 of 516 children with CAP. Conclusion: Our study shows that IS is an adequate sample for the diagnosis of CAP in pediatric population that required hospitalization. The procedure was safe, well tolerated, and with better diagnostic yields compared with the rest of the samples obtained. Mención de responsabilidad : Zulma Vanessa Rueda, Marcela Bermúdez, Andrea Restrepo, Carlos Garcés, Olga Morales, Claudia Roya-Pabón, Luisa Fernanda Carmona, Catalina Arango, Jose Luis Albarracín, Lucelly López, Yudy Aguilar, María Angélica Maya, Mónica Trujillo, Ángela Rocio Copete, Cristian Vera, Mariana Herrera, Margarita Rosa Giraldo, Gloria Isabel Niño-Cruz, Lázaro A Vélez Referencia : Int J Infect Dis. 2022 Jan 19;116:348-354. DOI (Digital Object Identifier) : 10.1016/j.ijid.2022.01.026 PMID : 35063681 Derechos de uso : CC BY-NC-ND En línea : https://linkinghub.elsevier.com/retrieve/pii/S1201-9712(22)00025-X Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=6010

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Human melioidosis reported by ProMED / Franco Eduardo Montúfar Andrade    

Público ISBD Título : Human melioidosis reported by ProMED Tipo de documento : documento electrónico Autores : Franco Eduardo Montúfar Andrade, Fecha de publicación : 2015 Títulos uniformes : International Journal of Infectious Diseases Idioma : Inglés (eng) Palabras clave : Melioidosis  ProMED. epidemiology Resumen : Objective: There are limited sources describing the global burden of emerging diseases. A review of human melioidosis reported by ProMED was performed and the reliability of the data retrieved assessed in comparison to published reports. The effectiveness of ProMED was evaluated as a source of epidemiological data by focusing on melioidosis. Methods: Using the keyword ‘melioidosis’ in the ProMED search engine, all of the information from the reports and collected data was reviewed using a structured form, including the year, country, gender, occupation, number of infected individuals, and number of fatal cases. Results: One hundred and twenty-four entries reported between January 1995 and October 2014 were identified. A total of 4630 cases were reported, with death reported in 505 cases, suggesting a misleadingly low overall case fatality rate (CFR) of 11%. Of 20 cases for which the gender was reported, 12 (60%) were male. Most of the cases were reported from Australia, Thailand, Singapore, Vietnam, and Malaysia, with sporadic reports from other countries. Conclusions: Internet-based reporting systems such as ProMED are useful to gather information and synthesize knowledge on emerging infections. Although certain areas need to be improved, ProMED provided good information about melioidosis. Mención de responsabilidad : Katherinn Melissa Nasner-Posso, Stefania Cruz-Calderón, Franco E Montúfar-Andrade, David A B Dance, Alfonso J Rodriguez-Morales Referencia : Int J Infect Dis. 2015 Jun;35:103-6. DOI (Digital Object Identifier) : 10.1016/j.ijid.2015.05.009 PMID : 25975651 Derechos de uso : CC BY En línea : https://www.ijidonline.com/article/S1201-9712(15)00116-2/fulltext Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3899 Human melioidosis reported by ProMED [documento electrónico] / Franco Eduardo Montúfar Andrade,  . - 2015. Obra : International Journal of Infectious Diseases Idioma : Inglés (eng) Palabras clave : Melioidosis  ProMED. epidemiology Resumen : Objective: There are limited sources describing the global burden of emerging diseases. A review of human melioidosis reported by ProMED was performed and the reliability of the data retrieved assessed in comparison to published reports. The effectiveness of ProMED was evaluated as a source of epidemiological data by focusing on melioidosis. Methods: Using the keyword ‘melioidosis’ in the ProMED search engine, all of the information from the reports and collected data was reviewed using a structured form, including the year, country, gender, occupation, number of infected individuals, and number of fatal cases. Results: One hundred and twenty-four entries reported between January 1995 and October 2014 were identified. A total of 4630 cases were reported, with death reported in 505 cases, suggesting a misleadingly low overall case fatality rate (CFR) of 11%. Of 20 cases for which the gender was reported, 12 (60%) were male. Most of the cases were reported from Australia, Thailand, Singapore, Vietnam, and Malaysia, with sporadic reports from other countries. Conclusions: Internet-based reporting systems such as ProMED are useful to gather information and synthesize knowledge on emerging infections. Although certain areas need to be improved, ProMED provided good information about melioidosis. Mención de responsabilidad : Katherinn Melissa Nasner-Posso, Stefania Cruz-Calderón, Franco E Montúfar-Andrade, David A B Dance, Alfonso J Rodriguez-Morales Referencia : Int J Infect Dis. 2015 Jun;35:103-6. DOI (Digital Object Identifier) : 10.1016/j.ijid.2015.05.009 PMID : 25975651 Derechos de uso : CC BY En línea : https://www.ijidonline.com/article/S1201-9712(15)00116-2/fulltext Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3899

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“Melioidosis in Antioquia, Colombia: an emerging or endemic disease? A cases series” / Franco Eduardo Montúfar Andrade    

Público ISBD Título : “Melioidosis in Antioquia, Colombia: an emerging or endemic disease? A cases series” Tipo de documento : documento electrónico Autores : Franco Eduardo Montúfar Andrade, Fecha de publicación : 2015 Títulos uniformes : International Journal of Infectious Diseases Idioma : Inglés (eng) Palabras clave : Melioidosis  sepsis  pneumonia  burkholderia pseudomallei Resumen : Background: Melioidosis is endemic in Malaysia, the southwest of Thailand, and northern Australia. The incidence in Thailand is 4.4/1 000 000 inhabitants, where it causes 19% of community-acquired pneumonia (CAP) and 20% of bacteremic pneumonia, and the mortality is 50%. Sporadic cases have been described in Central and South America. The objective of this study was to describe the clinical and epidemiological features and ecological characteristics of melioidosis in Antioquia, Colombia. Methods: This is a case series description. Results: Seven cases were identified. Burkholderia pseudomallei was isolated from peripheral blood, pleural fluid, and urine and was identified by the automated system VITEK 2 (bioMe ́ rieux) and API 20NE biochemical kit. Five of the cases had a bacteremic form with shock and pulmonary compromise and two of these patients died. The non-bacteremic melioidosis cases had genitourinary, abdominal, and osteoarticular compromise. All patients had comorbidities and lived in rural hot and humid areas in the west central region of Colombia (Antioquia). Diabetes mellitus, renal insufficiency, and other chronic diseases are important risk factors for the development of severe forms. Conclusions: The cases presented here are similar to those occurring in endemic areas regarding comorbidity, risk factors, clinical presentation, and environmental conditions. It is necessary to establish whether melioidosis is an endemic and under-diagnosed disease or an emerging disease in Colombia. Mención de responsabilidad : F E Montúfar, J E Ochoa, H Ortega, L Franco, M C Montúfar, A Monsalve, C Jaramillo, M Zapata Referencia : Int J Infect Dis. 2015 Aug;37:50-7. DOI (Digital Object Identifier) : 10.1016/j.ijid.2015.05.023 PMID : 26051974 Derechos de uso : CC BY-NC-ND En línea : http://www.ijidonline.com/article/S1201-9712(15)00132-0/fulltext Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3896 “Melioidosis in Antioquia, Colombia: an emerging or endemic disease? A cases series” [documento electrónico] / Franco Eduardo Montúfar Andrade,  . - 2015. Obra : International Journal of Infectious Diseases Idioma : Inglés (eng) Palabras clave : Melioidosis  sepsis  pneumonia  burkholderia pseudomallei Resumen : Background: Melioidosis is endemic in Malaysia, the southwest of Thailand, and northern Australia. The incidence in Thailand is 4.4/1 000 000 inhabitants, where it causes 19% of community-acquired pneumonia (CAP) and 20% of bacteremic pneumonia, and the mortality is 50%. Sporadic cases have been described in Central and South America. The objective of this study was to describe the clinical and epidemiological features and ecological characteristics of melioidosis in Antioquia, Colombia. Methods: This is a case series description. Results: Seven cases were identified. Burkholderia pseudomallei was isolated from peripheral blood, pleural fluid, and urine and was identified by the automated system VITEK 2 (bioMe ́ rieux) and API 20NE biochemical kit. Five of the cases had a bacteremic form with shock and pulmonary compromise and two of these patients died. The non-bacteremic melioidosis cases had genitourinary, abdominal, and osteoarticular compromise. All patients had comorbidities and lived in rural hot and humid areas in the west central region of Colombia (Antioquia). Diabetes mellitus, renal insufficiency, and other chronic diseases are important risk factors for the development of severe forms. Conclusions: The cases presented here are similar to those occurring in endemic areas regarding comorbidity, risk factors, clinical presentation, and environmental conditions. It is necessary to establish whether melioidosis is an endemic and under-diagnosed disease or an emerging disease in Colombia. Mención de responsabilidad : F E Montúfar, J E Ochoa, H Ortega, L Franco, M C Montúfar, A Monsalve, C Jaramillo, M Zapata Referencia : Int J Infect Dis. 2015 Aug;37:50-7. DOI (Digital Object Identifier) : 10.1016/j.ijid.2015.05.023 PMID : 26051974 Derechos de uso : CC BY-NC-ND En línea : http://www.ijidonline.com/article/S1201-9712(15)00132-0/fulltext Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=3896

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