Inicio
Detalle del título uniforme
Seizure
Tipo de obra :
Autre
Naturaleza de la obra :
Oeuvre
|
Documentos disponibles con este título uniforme (5)
Clasificado(s) por (Año de edición descendente) Refinar búsquedaValidation of the Status epilepticus severity score (STESS) at high-complexity hospitals in Medellín, Colombia / Lady Diana Ladino Malagón
Título : Validation of the Status epilepticus severity score (STESS) at high-complexity hospitals in Medellín, Colombia Tipo de documento : documento electrónico Autores : Lady Diana Ladino Malagón, Fecha de publicación : 2020 Títulos uniformes : Seizure Idioma : Inglés (eng) Palabras clave : Complication Epilepsy Death Outcome Prognosis Score Resumen : Purpose: The Status Epilepticus Severity Score (STESS) is one of the most well-known clinical scoring systems to predict mortality in status epilepticus (SE). The objective of this study was to validate STESS in a Colombian population. Method: We evaluated historical data of adult patients (age ≥16 years) with a clinical or electroencephalographic diagnosis of SE admitted between 2014 and 2017. Prospectively, we included patients admitted from January to June of 2018. The primary outcome was in-hospital mortality. Receiver operating characteristic (ROC)-analysis, determination of best cutoff values, sensitivity, specificity, and positive and negative likelihood ratios were performed. Results: The sample was 395 patients, with in-hospital mortality of 16.8 %. The area under the ROC curve for STESS was 0.84. A cutoff point of ≥3 produced the highest sensitivity of 84.9 % (95 % CI 73.9 %-92.5 %) and a specificity of 65.7 % (95 % CI 60.2 %–70.8 %), with a positive likelihood ratio of 2.5 and a negative likelihood ratio of 0.2. Conclusions: STESS is a useful tool to predict mortality in patients with SE. In Medellin, Colombia, a STESS Mención de responsabilidad : Juan Pablo Millán Sandoval, Luisa María Escobar del Rio, Edison Augusto Gómez, Lady Diana Ladino, Lina María López Ospina, Diana Marcela Díaz, José Fernando Zapata, Olga Helena Hernández Referencia : Seizure. 2020 Oct;81:287-291. DOI (Digital Object Identifier) : 10.1016/j.seizure.2020.08.020 PMID : 32927243 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1059131120302570 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5139 Validation of the Status epilepticus severity score (STESS) at high-complexity hospitals in Medellín, Colombia [documento electrónico] / Lady Diana Ladino Malagón, . - 2020.
Obra : Seizure
Idioma : Inglés (eng)
Palabras clave : Complication Epilepsy Death Outcome Prognosis Score Resumen : Purpose: The Status Epilepticus Severity Score (STESS) is one of the most well-known clinical scoring systems to predict mortality in status epilepticus (SE). The objective of this study was to validate STESS in a Colombian population. Method: We evaluated historical data of adult patients (age ≥16 years) with a clinical or electroencephalographic diagnosis of SE admitted between 2014 and 2017. Prospectively, we included patients admitted from January to June of 2018. The primary outcome was in-hospital mortality. Receiver operating characteristic (ROC)-analysis, determination of best cutoff values, sensitivity, specificity, and positive and negative likelihood ratios were performed. Results: The sample was 395 patients, with in-hospital mortality of 16.8 %. The area under the ROC curve for STESS was 0.84. A cutoff point of ≥3 produced the highest sensitivity of 84.9 % (95 % CI 73.9 %-92.5 %) and a specificity of 65.7 % (95 % CI 60.2 %–70.8 %), with a positive likelihood ratio of 2.5 and a negative likelihood ratio of 0.2. Conclusions: STESS is a useful tool to predict mortality in patients with SE. In Medellin, Colombia, a STESS Mención de responsabilidad : Juan Pablo Millán Sandoval, Luisa María Escobar del Rio, Edison Augusto Gómez, Lady Diana Ladino, Lina María López Ospina, Diana Marcela Díaz, José Fernando Zapata, Olga Helena Hernández Referencia : Seizure. 2020 Oct;81:287-291. DOI (Digital Object Identifier) : 10.1016/j.seizure.2020.08.020 PMID : 32927243 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1059131120302570 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5139 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001404 AC-2020-076 Archivo digital Producción Científica Artículos científicos Disponible
Título : Risk factors associated with drug resistant focal epilepsy in adults: A case control study Tipo de documento : documento electrónico Autores : Lady Diana Ladino Malagón, Fecha de publicación : 2019 Títulos uniformes : Seizure Idioma : Inglés (eng) Palabras clave : Complex partial seizure Focal seizure Intractable epilepsy Refractory epilepsy Risk factor Temporal lobe epilepsy Resumen : Purpose: Using an adult cohort of patients with focal epilepsy, we aimed to identify risk factors for development of drug-resistant epilepsy, which if identifiable would allow patients to receive appropriate counsel and earlier surgical treatment. Methods: This is a case-control study nested within a cohort, 146 adult patients with focal epilepsy were included. Definitions were used in accordance with ILAE criteria. The odds ratio and its confidence interval were calculated. We performed a logistic regression analysis. Results: Seventy-one [48.6%] patients met the criteria for drug-resistant epilepsy [cases] and 75 [51.4%] patients were controls. The mean age of patients was 44.5 ± 16.4 years. The most significant variables associated with developing drug-resistant epilepsy include younger age at diagnosis [18.75 vs. 32.2, p Mención de responsabilidad : Pragma Laboni Roy, Lizbeth Hernandez Ronquillo, Lady Diana Ladino, Jose F Tellez-Zenteno Referencia : Seizure. 2019;73:46–50. DOI (Digital Object Identifier) : 10.1016/j.seizure.2019.10.020 PMID : 31734466 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1059-1311(19)30390-5 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5081 Risk factors associated with drug resistant focal epilepsy in adults: A case control study [documento electrónico] / Lady Diana Ladino Malagón, . - 2019.
Obra : Seizure
Idioma : Inglés (eng)
Palabras clave : Complex partial seizure Focal seizure Intractable epilepsy Refractory epilepsy Risk factor Temporal lobe epilepsy Resumen : Purpose: Using an adult cohort of patients with focal epilepsy, we aimed to identify risk factors for development of drug-resistant epilepsy, which if identifiable would allow patients to receive appropriate counsel and earlier surgical treatment. Methods: This is a case-control study nested within a cohort, 146 adult patients with focal epilepsy were included. Definitions were used in accordance with ILAE criteria. The odds ratio and its confidence interval were calculated. We performed a logistic regression analysis. Results: Seventy-one [48.6%] patients met the criteria for drug-resistant epilepsy [cases] and 75 [51.4%] patients were controls. The mean age of patients was 44.5 ± 16.4 years. The most significant variables associated with developing drug-resistant epilepsy include younger age at diagnosis [18.75 vs. 32.2, p Mención de responsabilidad : Pragma Laboni Roy, Lizbeth Hernandez Ronquillo, Lady Diana Ladino, Jose F Tellez-Zenteno Referencia : Seizure. 2019;73:46–50. DOI (Digital Object Identifier) : 10.1016/j.seizure.2019.10.020 PMID : 31734466 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1059-1311(19)30390-5 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=5081 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD001311 AC-2020-015 Archivo digital Producción Científica Artículos científicos Disponible
Título : Efficacy of lacosamide in children and adolescents with drug-resistant epilepsy and refractory status epilepticus: A systematic review Tipo de documento : documento electrónico Autores : Lady Diana Ladino Malagón, Fecha de publicación : 2018 Títulos uniformes : Seizure Idioma : Inglés (eng) Palabras clave : Adds-on therapy behavior efficacy refractory epilepsy safety side effect Resumen : Purpose: Lacosamide, is one of the newer antiepileptic drug approved for focal drug-resistant epilepsy as an add-on treatment in patients older than 16 years. However, there is growing evidence of its use, safety and efficacy in children. We aim to evaluate efficacy and tolerability of lacosamide in focal and generalized drug-resistant epilepsy and refractory status epilepticus in the pediatric population. Methods: We conducted a systematic review on MEDLINE, EMBASE, COCHRANE, Google Scholar and Scielo from January 2008 to January 2017. The primary outcome was the efficacy of lacosamide in children with drug-resistant epilepsy and refractory status epilepticus. Efficacy and adverse events attributed to lacosamide were extracted from each publication and systematically reported. We performed no meta-analyses due to limited available data. Results: Of 175 abstracts identified by the search, 82 were reviewed as full-text. Twenty-six articles fulfilled eligibility criteria and described outcomes in 797 patients (57% male). The majority of studies were retrospective (69%) small series (84%). On average 51% of patients had 50% or greater seizure reduction. The mean seizure freedom rate was 24%. Adverse effects occurred in 18–59% of patients. The main events were dizziness, sedation, gastrointestinal upset, mood and behavioral changes. Half of the patients with Lennox Gastaut syndrome showed 50% or greater seizure reduction, 32% did not response to lacosamide and 17% suffered seizure aggravation. Conclusion: Current evidence shows lacosamide as a good option in pediatric patients with focal drug-resistant epilepsy and refractory status epilepticus as an add-on therapy given its efficacy on seizure control and safety profile. The use of lacosamide in Lennox-Gastaut syndrome shows conflicting data. Large randomized controlled studies in the pediatric population are necessary to substantiate these findings. Mención de responsabilidad : Johann Sebastián Ortiz de la Rosa, Lady Diana Ladino, Paula Juliana Rodríguez, María Camila Rueda, Juan Pablo Polanía, Angie Catalina Castañeda Referencia : Seizure. 2018 Mar;56:34-40. DOI (Digital Object Identifier) : 10.1016/j.seizure.2018.01.014 PMID : 29428899 En línea : https://www.seizure-journal.com/article/S1059-1311(17)30689-1/fulltext Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4191 Efficacy of lacosamide in children and adolescents with drug-resistant epilepsy and refractory status epilepticus: A systematic review [documento electrónico] / Lady Diana Ladino Malagón, . - 2018.
Obra : Seizure
Idioma : Inglés (eng)
Palabras clave : Adds-on therapy behavior efficacy refractory epilepsy safety side effect Resumen : Purpose: Lacosamide, is one of the newer antiepileptic drug approved for focal drug-resistant epilepsy as an add-on treatment in patients older than 16 years. However, there is growing evidence of its use, safety and efficacy in children. We aim to evaluate efficacy and tolerability of lacosamide in focal and generalized drug-resistant epilepsy and refractory status epilepticus in the pediatric population. Methods: We conducted a systematic review on MEDLINE, EMBASE, COCHRANE, Google Scholar and Scielo from January 2008 to January 2017. The primary outcome was the efficacy of lacosamide in children with drug-resistant epilepsy and refractory status epilepticus. Efficacy and adverse events attributed to lacosamide were extracted from each publication and systematically reported. We performed no meta-analyses due to limited available data. Results: Of 175 abstracts identified by the search, 82 were reviewed as full-text. Twenty-six articles fulfilled eligibility criteria and described outcomes in 797 patients (57% male). The majority of studies were retrospective (69%) small series (84%). On average 51% of patients had 50% or greater seizure reduction. The mean seizure freedom rate was 24%. Adverse effects occurred in 18–59% of patients. The main events were dizziness, sedation, gastrointestinal upset, mood and behavioral changes. Half of the patients with Lennox Gastaut syndrome showed 50% or greater seizure reduction, 32% did not response to lacosamide and 17% suffered seizure aggravation. Conclusion: Current evidence shows lacosamide as a good option in pediatric patients with focal drug-resistant epilepsy and refractory status epilepticus as an add-on therapy given its efficacy on seizure control and safety profile. The use of lacosamide in Lennox-Gastaut syndrome shows conflicting data. Large randomized controlled studies in the pediatric population are necessary to substantiate these findings. Mención de responsabilidad : Johann Sebastián Ortiz de la Rosa, Lady Diana Ladino, Paula Juliana Rodríguez, María Camila Rueda, Juan Pablo Polanía, Angie Catalina Castañeda Referencia : Seizure. 2018 Mar;56:34-40. DOI (Digital Object Identifier) : 10.1016/j.seizure.2018.01.014 PMID : 29428899 En línea : https://www.seizure-journal.com/article/S1059-1311(17)30689-1/fulltext Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4191 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000805 AC-2018-092 Archivo digital Producción Científica Artículos científicos Disponible
Título : Experience of psychogenic nonepileptic seizures in the Canadian league against epilepsy: A survey describing current practices by neurologists and epileptologists Tipo de documento : documento electrónico Autores : Lady Diana Ladino Malagón, Fecha de publicación : 2018 Títulos uniformes : Seizure Idioma : Inglés (eng) Palabras clave : Conversion disorder Functional seizures Nonepileptic attacks Pseudoseizures Psychotherapy Resumen : Purpose: Psychogenic nonepileptic seizures (PNES) are one of the most common differential diagnoses of epilepsy. Our objective is to describe current medical care in Canada and identify patterns of practice and service gaps. Methods: In 2015, a 36-question survey was sent via email to the 131 members of the Canadian League Against Epilepsy. The questions were designed after literature review and discussion with the ILAE PNES Task Force. Questions were separated into 5 sections: 1) the role of the respondent and their exposure to PNES, 2) diagnostic methods, 3) management of PNES, 4) etiological factors, and 5) problems accessing health care. Results: Sixty-two questionnaires were analyzed (response rate: 47%). Most respondents were epileptologists (76%). The majority of respondents personally diagnosed PNES and communicated the diagnosis to the patient, but only 55% provided follow-up within their practice and only 50% recommended or arranged treatment. Many (35%) were either unfamiliar with the diagnosis of PNES or inexperienced in arranging or offering treatment. Most (79%) provided follow-up to patients with concomitant epilepsy, but when PNES was the sole diagnosis follow-up rates were low. Although 84% of respondents felt that individualized psychological therapy was the most effective treatment, 40% of patients were not referred to psychotherapy and in most cases availability such therapy was low (30–60%). Conclusions: Canadian health professionals’ understanding of PNES mostly reflects current international expert opinion. Once diagnosis is made however, the majority of patients are discharged from neurological services without appropriate psychological care. Mención de responsabilidad : Alexandra Carter, Alyssa Denton, Lady D Ladino, Islam Hassan, Tyson Sawchuk, Thomas Snyder, Mirna Vrbancic, Markus Reuber, Richard Huntsman, Jose F Tellez-Zenteno, PNES Canada Group Referencia : Seizure. 2018 Oct;61:227-233. DOI (Digital Object Identifier) : 10.1016/j.seizure.2018.08.025 PMID : 30227342 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1059-1311(18)30315-7 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4151 Experience of psychogenic nonepileptic seizures in the Canadian league against epilepsy: A survey describing current practices by neurologists and epileptologists [documento electrónico] / Lady Diana Ladino Malagón, . - 2018.
Obra : Seizure
Idioma : Inglés (eng)
Palabras clave : Conversion disorder Functional seizures Nonepileptic attacks Pseudoseizures Psychotherapy Resumen : Purpose: Psychogenic nonepileptic seizures (PNES) are one of the most common differential diagnoses of epilepsy. Our objective is to describe current medical care in Canada and identify patterns of practice and service gaps. Methods: In 2015, a 36-question survey was sent via email to the 131 members of the Canadian League Against Epilepsy. The questions were designed after literature review and discussion with the ILAE PNES Task Force. Questions were separated into 5 sections: 1) the role of the respondent and their exposure to PNES, 2) diagnostic methods, 3) management of PNES, 4) etiological factors, and 5) problems accessing health care. Results: Sixty-two questionnaires were analyzed (response rate: 47%). Most respondents were epileptologists (76%). The majority of respondents personally diagnosed PNES and communicated the diagnosis to the patient, but only 55% provided follow-up within their practice and only 50% recommended or arranged treatment. Many (35%) were either unfamiliar with the diagnosis of PNES or inexperienced in arranging or offering treatment. Most (79%) provided follow-up to patients with concomitant epilepsy, but when PNES was the sole diagnosis follow-up rates were low. Although 84% of respondents felt that individualized psychological therapy was the most effective treatment, 40% of patients were not referred to psychotherapy and in most cases availability such therapy was low (30–60%). Conclusions: Canadian health professionals’ understanding of PNES mostly reflects current international expert opinion. Once diagnosis is made however, the majority of patients are discharged from neurological services without appropriate psychological care. Mención de responsabilidad : Alexandra Carter, Alyssa Denton, Lady D Ladino, Islam Hassan, Tyson Sawchuk, Thomas Snyder, Mirna Vrbancic, Markus Reuber, Richard Huntsman, Jose F Tellez-Zenteno, PNES Canada Group Referencia : Seizure. 2018 Oct;61:227-233. DOI (Digital Object Identifier) : 10.1016/j.seizure.2018.08.025 PMID : 30227342 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1059-1311(18)30315-7 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4151 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000765 AC-2018-052 Archivo digital Producción Científica Artículos científicos Disponible
Título : Epidemiology of early stages of epilepsy: Risk of seizure recurrence after a first seizure Tipo de documento : documento electrónico Autores : Lady Diana Ladino Malagón, Fecha de publicación : 2017 Títulos uniformes : Seizure Idioma : Inglés (eng) Palabras clave : Diagnosis Epidemiology First seizure Recurrence Single seizure Unprovoked seizure Resumen : A single unprovoked seizure is a frequent phenomenon in the general population and the rate of seizure recurrence can vary widely. Individual risk prognostication is crucial in predicting patient outcomes and guiding treatment decisions. In this article, we review the most important risk factors associated with an increased likelihood of seizure recurrence after a single unprovoked seizure. In summary, the presence of focal seizure, nocturnal seizure, history of prior brain injury, family history of epilepsy, abnormal neurological exam, epileptiform discharges on electroencephalography and neuroimaging abnormalities, portend increased risk of seizure recurrence. Elucidation of these risk factors in patient assessment will augment clinical decision-making and may help determine the appropriateness of instituting anti-epilepsy treatment. We also discuss the Canadian model of single seizure clinics and the potential use to assess these patients. Mención de responsabilidad : Syed Rizvi, Lady Diana Ladino, Lizbeth Hernandez-Ronquillo, José F Téllez-Zenteno Referencia : Seizure. 2017 Jul;49:46-53. DOI (Digital Object Identifier) : 10.1016/j.seizure.2017.02.006 PMID : 28242175 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1059-1311(17)30118-8 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4033 Epidemiology of early stages of epilepsy: Risk of seizure recurrence after a first seizure [documento electrónico] / Lady Diana Ladino Malagón, . - 2017.
Obra : Seizure
Idioma : Inglés (eng)
Palabras clave : Diagnosis Epidemiology First seizure Recurrence Single seizure Unprovoked seizure Resumen : A single unprovoked seizure is a frequent phenomenon in the general population and the rate of seizure recurrence can vary widely. Individual risk prognostication is crucial in predicting patient outcomes and guiding treatment decisions. In this article, we review the most important risk factors associated with an increased likelihood of seizure recurrence after a single unprovoked seizure. In summary, the presence of focal seizure, nocturnal seizure, history of prior brain injury, family history of epilepsy, abnormal neurological exam, epileptiform discharges on electroencephalography and neuroimaging abnormalities, portend increased risk of seizure recurrence. Elucidation of these risk factors in patient assessment will augment clinical decision-making and may help determine the appropriateness of instituting anti-epilepsy treatment. We also discuss the Canadian model of single seizure clinics and the potential use to assess these patients. Mención de responsabilidad : Syed Rizvi, Lady Diana Ladino, Lizbeth Hernandez-Ronquillo, José F Téllez-Zenteno Referencia : Seizure. 2017 Jul;49:46-53. DOI (Digital Object Identifier) : 10.1016/j.seizure.2017.02.006 PMID : 28242175 En línea : https://linkinghub.elsevier.com/retrieve/pii/S1059-1311(17)30118-8 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4033 Reserva
Reservar este documentoEjemplares(1)
Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000629 AC-2017-018 Archivo digital Producción Científica Artículos científicos Disponible
