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Journal of Medical and Veterinary Mycology
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Documentos disponibles con este título uniforme (19)
Clasificado(s) por (Año de edición descendente) Refinar búsquedaCourse of the experimental murine infection induced by sporothrix schenckii conidia according to depth of inoculation / Fabio Uribe Jaramillo ; Ángela Inés Zuluaga Cadena ; Ángela Restrepo Moreno
Título : Course of the experimental murine infection induced by sporothrix schenckii conidia according to depth of inoculation Tipo de documento : documento electrónico Autores : Fabio Uribe Jaramillo, ; Ángela Inés Zuluaga Cadena, ; Ángela Restrepo Moreno, Fecha de publicación : 1993 Títulos uniformes : Journal of Medical and Veterinary Mycology Idioma : Inglés (eng) Resumen : Balb/c mice were infected intradermally (ID) or subcutaneously (SC) with Sporothrix schenckii conidia, in an attempt to demonstrate the role played by the depth of inoculation on the course of the infectious process. Animals were observed weekly up to 6 weeks and the time of appearance, as well as the aspect of the lesions, was recorded. Thirty percent of the animals were autopsied and their organs subjected to histopathological study. All animals, irrespective of the route of inoculation, developed clinically detectable sporotrichosis; the resulting lesions (nodules, drained or undrained abscesses, pustules) tended towards spontaneous healing; most of the ID-inoculated mice healed after 3 weeks post-infection while the SC group took longer (5 weeks). Histologically, all the animals that were killed had inflammatory foci, but a larger proportion (57%) of those infected SC exhibited granuloma formation in comparison with the animals infected by the ID route (16·6%). During the first week post-inoculation, the enlargement of the inguinal lymph node did not coincide with the presence of histologically detectable hypertrophy; however, after 2 weeks, 70–80% of all animals had both types of abnormality. Our results indicate that irrespective of the route of inoculation all the mice developed clinically and histologically detectable sporotrichosis, albeit of a limited character. Mención de responsabilidad : S. Restrepo-Gutierrez, M. Arango-Arteaga, F. Uribe-Jaramillo, A.I. Zuluaga-Cadena, A. Restrepo-Moreno DOI (Digital Object Identifier) : 10.1080/02681219380000541 En línea : https://academic.oup.com/mmy/article-abstract/31/6/411/988315 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4371 Course of the experimental murine infection induced by sporothrix schenckii conidia according to depth of inoculation [documento electrónico] / Fabio Uribe Jaramillo, ; Ángela Inés Zuluaga Cadena, ; Ángela Restrepo Moreno, . - 1993.
Obra : Journal of Medical and Veterinary Mycology
Idioma : Inglés (eng)
Resumen : Balb/c mice were infected intradermally (ID) or subcutaneously (SC) with Sporothrix schenckii conidia, in an attempt to demonstrate the role played by the depth of inoculation on the course of the infectious process. Animals were observed weekly up to 6 weeks and the time of appearance, as well as the aspect of the lesions, was recorded. Thirty percent of the animals were autopsied and their organs subjected to histopathological study. All animals, irrespective of the route of inoculation, developed clinically detectable sporotrichosis; the resulting lesions (nodules, drained or undrained abscesses, pustules) tended towards spontaneous healing; most of the ID-inoculated mice healed after 3 weeks post-infection while the SC group took longer (5 weeks). Histologically, all the animals that were killed had inflammatory foci, but a larger proportion (57%) of those infected SC exhibited granuloma formation in comparison with the animals infected by the ID route (16·6%). During the first week post-inoculation, the enlargement of the inguinal lymph node did not coincide with the presence of histologically detectable hypertrophy; however, after 2 weeks, 70–80% of all animals had both types of abnormality. Our results indicate that irrespective of the route of inoculation all the mice developed clinically and histologically detectable sporotrichosis, albeit of a limited character. Mención de responsabilidad : S. Restrepo-Gutierrez, M. Arango-Arteaga, F. Uribe-Jaramillo, A.I. Zuluaga-Cadena, A. Restrepo-Moreno DOI (Digital Object Identifier) : 10.1080/02681219380000541 En línea : https://academic.oup.com/mmy/article-abstract/31/6/411/988315 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4371 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000871 AC-1993-005 Archivo digital Producción Científica Artículos científicos Disponible
Título : Detection of proteolytic enzymes released by the dimorphic fungus Paracoccidioides brasiliensis Tipo de documento : documento electrónico Autores : Victoria Inés Bedoya Escobar, ; María Soledad Naranjo Mesa, ; Ángela Restrepo Moreno, Fecha de publicación : 1993 Títulos uniformes : Journal of Medical and Veterinary Mycology Idioma : Inglés (eng) Resumen : The release of proteolytic enzymes with elastinolytic and collagenolytic activity was investigated in 10 different isolates of Paracoccidioides brasiliensis. The study encompassed both the mycelial and the yeast phase of the fungus. In the mycelial phase, secretion of elastinolytic and collagenolytic enzymes was demonstrated in 70% and 80% of the isolates, respectively. None of the isolates in the yeast phase exhibited elastinolytic activity, but 90% showed collagenolytic activity. These results demonstrate that the dimorphic fungus P. brasiliensis has the ability to release proteolytic enzymes in both growth phases, although with apparently different specificities. Mención de responsabilidad : V.I. Bedoya-Escobar, M.S. Naranjo-Mesa & A. Restrepo-Moreno DOI (Digital Object Identifier) : 10.1080/02681219380000361 En línea : https://www.tandfonline.com/doi/abs/10.1080/02681219380000361 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4370 Detection of proteolytic enzymes released by the dimorphic fungus Paracoccidioides brasiliensis [documento electrónico] / Victoria Inés Bedoya Escobar, ; María Soledad Naranjo Mesa, ; Ángela Restrepo Moreno, . - 1993.
Obra : Journal of Medical and Veterinary Mycology
Idioma : Inglés (eng)
Resumen : The release of proteolytic enzymes with elastinolytic and collagenolytic activity was investigated in 10 different isolates of Paracoccidioides brasiliensis. The study encompassed both the mycelial and the yeast phase of the fungus. In the mycelial phase, secretion of elastinolytic and collagenolytic enzymes was demonstrated in 70% and 80% of the isolates, respectively. None of the isolates in the yeast phase exhibited elastinolytic activity, but 90% showed collagenolytic activity. These results demonstrate that the dimorphic fungus P. brasiliensis has the ability to release proteolytic enzymes in both growth phases, although with apparently different specificities. Mención de responsabilidad : V.I. Bedoya-Escobar, M.S. Naranjo-Mesa & A. Restrepo-Moreno DOI (Digital Object Identifier) : 10.1080/02681219380000361 En línea : https://www.tandfonline.com/doi/abs/10.1080/02681219380000361 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4370 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000870 AC-1993-004 Archivo digital Producción Científica Artículos científicos Disponible
Título : Disseminated adiaspiromycosis in a patient with AIDS Tipo de documento : documento electrónico Autores : Luz Elena Cano Restrepo, ; Ángela Restrepo Moreno, Fecha de publicación : 1993 Títulos uniformes : Journal of Medical and Veterinary Mycology Idioma : Inglés (eng) Resumen : A case of disseminated adiaspiromycosis in an AIDS patient is described. The most notable characteristic of the infection was the extensive osteomyelitis exhibited by the patient. Positive cultures for Chrysosporium parvum var. parvum were obtained from pus taken from a lesion of the wrist during surgery as well as from sputum samples and a bone marrow aspirate. Treatment with amphotericin B controlled the fungal infection. Mención de responsabilidad : E. Echavarria, E.L. Cano, A. Restrepo Referencia : J Med Vet Mycol. 1993;31(1):91-7. DOI (Digital Object Identifier) : 10.1080/02681219380000101 PMID : 8483061 En línea : https://academic.oup.com/mmy/article-abstract/31/1/91/942394 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4369 Disseminated adiaspiromycosis in a patient with AIDS [documento electrónico] / Luz Elena Cano Restrepo, ; Ángela Restrepo Moreno, . - 1993.
Obra : Journal of Medical and Veterinary Mycology
Idioma : Inglés (eng)
Resumen : A case of disseminated adiaspiromycosis in an AIDS patient is described. The most notable characteristic of the infection was the extensive osteomyelitis exhibited by the patient. Positive cultures for Chrysosporium parvum var. parvum were obtained from pus taken from a lesion of the wrist during surgery as well as from sputum samples and a bone marrow aspirate. Treatment with amphotericin B controlled the fungal infection. Mención de responsabilidad : E. Echavarria, E.L. Cano, A. Restrepo Referencia : J Med Vet Mycol. 1993;31(1):91-7. DOI (Digital Object Identifier) : 10.1080/02681219380000101 PMID : 8483061 En línea : https://academic.oup.com/mmy/article-abstract/31/1/91/942394 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4369 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000869 AC-1993-002 Archivo digital Producción Científica Artículos científicos Disponible
Título : Development of pulmonary fibrosis in mice during infection with Paracoccidioides brasiliensis conidia Tipo de documento : documento electrónico Autores : Susana Restrepo, ; Ángela María Tobón Orozco, ; Ángela Restrepo Moreno, Fecha de publicación : 1992 Títulos uniformes : Journal of Medical and Veterinary Mycology Idioma : Inglés (eng) Resumen : Pulmonary fibrosis is a feared sequelae of paracoccidioidomycosis. We sought to determine if mice exposed to Paracoccidioides brasiliensis conidia would develop pulmonary fibrosis. BALB/c mice were infected intranasally with P. brasiliensis conidia and sacrificed at regular intervals. One lung was sectioned for histopathology and sections were stained with haematoxylin and eosin, trichromic and argentic stains; the other lung was homogenized and cultured to determine the viability of the fungus. One week post-challenge, only small peribronchial foci were apparent. After 4 weeks, reticular fibres appeared disorganized and disrupted. Six to 8 weeks later peribronchial infiltrates were larger and appeared surrounded by reticular fibres; thick collagen I fibres were noticed in the infiltrated areas at this time. On weeks 10–12, infiltrates were confluent and reticular fibres were concentrated around the inflammatory foci; collagenization was apparent. Observations up to 16 weeks revealed diffuse involvement of the lung parenchyma with extensive collagenization. Lung cultures were always positive. We suggest that inhalation of P. brasiliensis conidia induces adverse lung responses leading to changes in the proportion of collagen fibres I and III. Mención de responsabilidad : S. Restrepo, A. Tobon, J. Trujillo & A. Restrepo Referencia : J Med Vet Mycol. 1992;30(3):173-84. PMID : 1517956 En línea : https://www.tandfonline.com/doi/abs/10.1080/02681219280000241 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4366 Development of pulmonary fibrosis in mice during infection with Paracoccidioides brasiliensis conidia [documento electrónico] / Susana Restrepo, ; Ángela María Tobón Orozco, ; Ángela Restrepo Moreno, . - 1992.
Obra : Journal of Medical and Veterinary Mycology
Idioma : Inglés (eng)
Resumen : Pulmonary fibrosis is a feared sequelae of paracoccidioidomycosis. We sought to determine if mice exposed to Paracoccidioides brasiliensis conidia would develop pulmonary fibrosis. BALB/c mice were infected intranasally with P. brasiliensis conidia and sacrificed at regular intervals. One lung was sectioned for histopathology and sections were stained with haematoxylin and eosin, trichromic and argentic stains; the other lung was homogenized and cultured to determine the viability of the fungus. One week post-challenge, only small peribronchial foci were apparent. After 4 weeks, reticular fibres appeared disorganized and disrupted. Six to 8 weeks later peribronchial infiltrates were larger and appeared surrounded by reticular fibres; thick collagen I fibres were noticed in the infiltrated areas at this time. On weeks 10–12, infiltrates were confluent and reticular fibres were concentrated around the inflammatory foci; collagenization was apparent. Observations up to 16 weeks revealed diffuse involvement of the lung parenchyma with extensive collagenization. Lung cultures were always positive. We suggest that inhalation of P. brasiliensis conidia induces adverse lung responses leading to changes in the proportion of collagen fibres I and III. Mención de responsabilidad : S. Restrepo, A. Tobon, J. Trujillo & A. Restrepo Referencia : J Med Vet Mycol. 1992;30(3):173-84. PMID : 1517956 En línea : https://www.tandfonline.com/doi/abs/10.1080/02681219280000241 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4366 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000866 AC-1992-005 Archivo digital Producción Científica Artículos científicos Disponible
Título : Killing of Paracoccidioides brasiliensis conidia by pulmonary macrophages and the effect of cytokines Tipo de documento : documento electrónico Autores : Luz Elena Cano Restrepo, ; R. Arango, ; Maria E. Salazar, ; Ángela Restrepo Moreno, Fecha de publicación : 1992 Títulos uniformes : Journal of Medical and Veterinary Mycology Idioma : Inglés (eng) Resumen : The ability of conidia, the infectious form of the dimorphic fungus Paracoccidioides brasiliensis, to be killed in vitro by murine pulmonary macrophages was studied. Mice were immunized by intravenous injection of killed conidia, which resulted in cellular immunity demonstrated by delayed type hypersensitivity in vivo and macrophage migration inhibition factor production in vitro. Resident pulmonary macrophages from non-immune mice were able to significantly kill the conidia (28%). Such macrophages treated with supernatants (cytokines) from antigen-stimulated immune mononuclears had a markedly enhanced ability to kill conidia (73%). These results show that activated pulmonary macrophages are potent killers of conidia of P. brasiliensis and that immune mononuclears play a role in activation of macrophages. Activated macrophages may be important for pulmonary defense against the initial stages of infection with this fungus. Mención de responsabilidad : L.E. Cano, R. Arango, M.E. Salazar, E. Brummer, D.A. Stevens & A. Restrepo Referencia : J Med Vet Mycol. 1992;30(2):161-8. DOI (Digital Object Identifier) : 10.1080/02681219280000211 PMID : 1588466 En línea : https://www.tandfonline.com/doi/abs/10.1080/02681219280000211 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4365 Killing of Paracoccidioides brasiliensis conidia by pulmonary macrophages and the effect of cytokines [documento electrónico] / Luz Elena Cano Restrepo, ; R. Arango, ; Maria E. Salazar, ; Ángela Restrepo Moreno, . - 1992.
Obra : Journal of Medical and Veterinary Mycology
Idioma : Inglés (eng)
Resumen : The ability of conidia, the infectious form of the dimorphic fungus Paracoccidioides brasiliensis, to be killed in vitro by murine pulmonary macrophages was studied. Mice were immunized by intravenous injection of killed conidia, which resulted in cellular immunity demonstrated by delayed type hypersensitivity in vivo and macrophage migration inhibition factor production in vitro. Resident pulmonary macrophages from non-immune mice were able to significantly kill the conidia (28%). Such macrophages treated with supernatants (cytokines) from antigen-stimulated immune mononuclears had a markedly enhanced ability to kill conidia (73%). These results show that activated pulmonary macrophages are potent killers of conidia of P. brasiliensis and that immune mononuclears play a role in activation of macrophages. Activated macrophages may be important for pulmonary defense against the initial stages of infection with this fungus. Mención de responsabilidad : L.E. Cano, R. Arango, M.E. Salazar, E. Brummer, D.A. Stevens & A. Restrepo Referencia : J Med Vet Mycol. 1992;30(2):161-8. DOI (Digital Object Identifier) : 10.1080/02681219280000211 PMID : 1588466 En línea : https://www.tandfonline.com/doi/abs/10.1080/02681219280000211 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4365 Reserva
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