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Journal of Medical and Veterinary Mycology
Tipo de obra :
Autre
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Oeuvre
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Documentos disponibles con este título uniforme (19)
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Chronic murine paracoccidioidomycosis: Effect of ketoconazole on clearance of paracoccidioides brasiliensis and immune response / Guillermo L. Hoyos ; Juan Guillermo McEwen Ochoa ; Ángela Restrepo Moreno
Título : Chronic murine paracoccidioidomycosis: Effect of ketoconazole on clearance of paracoccidioides brasiliensis and immune response Tipo de documento : documento electrónico Autores : Guillermo L. Hoyos, ; Juan Guillermo McEwen Ochoa, ; Ángela Restrepo Moreno, Fecha de publicación : 1984 Títulos uniformes : Journal of Medical and Veterinary Mycology Idioma : Inglés (eng) Resumen : In a murine model of chronic pulmonary and disseminated paracoccidioidomycosis, ketoconazole (100 mg kg-1 in 0–3% agar) given by gavage twice daily for 1 or 2 months enabled all mice to clear disseminated Paracoccidioides brasiliensis from the spleen. Clearance of P. brasiliensis from the lungs was more difficult, and was achieved in 60% of the mice treated for 2 months. Sera from agar-treated control mice at days 77 and 103 post-infection demonstrated precipitating antibodies to P. brasiliensis antigens, but sera from ketoconazole-treated mice were precipitin-negative, indicating a favorable prognosis. Delayed hypersensitivity reactions to P. brasiliensis antigens in ketoconazole-treated mice were not significantly greater than in controls; consequently this test correlated less well with response than levels of serum antibody. This is the first use of this animal model of paracoccidioidomycosis to study the effect of antifungal drug protocols on the resolution of the disease. It also demonstrates the utility of this model in addressing clinically relevant questions about this disease and its treatment. Mención de responsabilidad : Guillermo L. Hoyos, Juan G. McEwen, Elmer Brummer, Elizabeth Castañeda, Angela Restrepo, David A. Stevens Referencia : Sabouraudia. 1984;22(5):419-26. DOI (Digital Object Identifier) : 10.1080/00362178485380671 PMID : 6095472 En línea : https://academic.oup.com/mmy/article-abstract/22/5/419/1628665 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4330 Chronic murine paracoccidioidomycosis: Effect of ketoconazole on clearance of paracoccidioides brasiliensis and immune response [documento electrónico] / Guillermo L. Hoyos, ; Juan Guillermo McEwen Ochoa, ; Ángela Restrepo Moreno, . - 1984.
Obra : Journal of Medical and Veterinary Mycology
Idioma : Inglés (eng)
Resumen : In a murine model of chronic pulmonary and disseminated paracoccidioidomycosis, ketoconazole (100 mg kg-1 in 0–3% agar) given by gavage twice daily for 1 or 2 months enabled all mice to clear disseminated Paracoccidioides brasiliensis from the spleen. Clearance of P. brasiliensis from the lungs was more difficult, and was achieved in 60% of the mice treated for 2 months. Sera from agar-treated control mice at days 77 and 103 post-infection demonstrated precipitating antibodies to P. brasiliensis antigens, but sera from ketoconazole-treated mice were precipitin-negative, indicating a favorable prognosis. Delayed hypersensitivity reactions to P. brasiliensis antigens in ketoconazole-treated mice were not significantly greater than in controls; consequently this test correlated less well with response than levels of serum antibody. This is the first use of this animal model of paracoccidioidomycosis to study the effect of antifungal drug protocols on the resolution of the disease. It also demonstrates the utility of this model in addressing clinically relevant questions about this disease and its treatment. Mención de responsabilidad : Guillermo L. Hoyos, Juan G. McEwen, Elmer Brummer, Elizabeth Castañeda, Angela Restrepo, David A. Stevens Referencia : Sabouraudia. 1984;22(5):419-26. DOI (Digital Object Identifier) : 10.1080/00362178485380671 PMID : 6095472 En línea : https://academic.oup.com/mmy/article-abstract/22/5/419/1628665 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4330 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000831 AC-1984-004 Archivo digital Producción Científica Artículos científicos Disponible Effect of temperature on the mycelium to yeast transformation of paracoccidioides brasiliensis / María Mercedes Patiño ; Luis C. Burgos ; Ángela Restrepo Moreno
Título : Effect of temperature on the mycelium to yeast transformation of paracoccidioides brasiliensis Tipo de documento : documento electrónico Autores : María Mercedes Patiño, ; Luis C. Burgos, ; Ángela Restrepo Moreno, Fecha de publicación : 1984 Títulos uniformes : Journal of Medical and Veterinary Mycology Idioma : Inglés (eng) Resumen : The influence of temperature on Paracoccidioides brasiliensis mycelium to yeast transformation was studied by sequential microscopic observations of slide cultures. When incubated at temperatures above 28°C, the mycelial elements gradually produced round to oval chlamydospores and later on, exhibited multiple budding. A sizeable proportion of mycelial elements transformed at 34°C; however, multiple budding was important only at 37°C. Mención de responsabilidad : María Mercedes Patiño, Luic C. Burgos, Angela Restrepo Referencia : Sabouraudia. 1984;22(6):509-11. DOI (Digital Object Identifier) : 10.1080/00362178485380801 PMID : 6523309 En línea : https://academic.oup.com/mmy/article-abstract/22/6/509/1625052 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4328 Effect of temperature on the mycelium to yeast transformation of paracoccidioides brasiliensis [documento electrónico] / María Mercedes Patiño, ; Luis C. Burgos, ; Ángela Restrepo Moreno, . - 1984.
Obra : Journal of Medical and Veterinary Mycology
Idioma : Inglés (eng)
Resumen : The influence of temperature on Paracoccidioides brasiliensis mycelium to yeast transformation was studied by sequential microscopic observations of slide cultures. When incubated at temperatures above 28°C, the mycelial elements gradually produced round to oval chlamydospores and later on, exhibited multiple budding. A sizeable proportion of mycelial elements transformed at 34°C; however, multiple budding was important only at 37°C. Mención de responsabilidad : María Mercedes Patiño, Luic C. Burgos, Angela Restrepo Referencia : Sabouraudia. 1984;22(6):509-11. DOI (Digital Object Identifier) : 10.1080/00362178485380801 PMID : 6523309 En línea : https://academic.oup.com/mmy/article-abstract/22/6/509/1625052 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4328 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000829 AC-1984-002 Archivo digital Producción Científica Artículos científicos Disponible Blood groups and HLA antigens in paracoccidioidomycosis / Fabiola Montoya de Restrepo ; Marcos Restrepo ; Ángela Restrepo Moreno
Título : Blood groups and HLA antigens in paracoccidioidomycosis Tipo de documento : documento electrónico Autores : Fabiola Montoya de Restrepo, ; Marcos Restrepo, ; Ángela Restrepo Moreno, Fecha de publicación : 1983 Títulos uniformes : Journal of Medical and Veterinary Mycology Idioma : Inglés (eng) Resumen : The frequencies of blood groups, Rh and HLA antigens were studied in a series of patients with paracoccidioidomycosis as well as in control subjects. Statistical analysis of the results showed that only 2 antigens (HLA-A9 and HLA-B13) had a significantly increased frequency among patients with paracoccidioidomycosis compared with healthy controls. Among patients with paracoccidioidomycosis antigen HLA-A9 was significantly more prevalent in progressive pulmonary forms of the disease than in patients with extra pulmonary involvement. These observations suggest that HLA-A9 may influence susceptibility to the mycosis as well as its course. Mención de responsabilidad : Fabiola Montoya de Restrepo, Marcos Restrepo, Angela Restrepo Referencia : Sabouraudia. 1983 Mar;21(1):35-9. DOI (Digital Object Identifier) : 10.1080/00362178385380061 PMID : 6405491 En línea : https://academic.oup.com/mmy/article-abstract/21/1/35/1640462 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4326 Blood groups and HLA antigens in paracoccidioidomycosis [documento electrónico] / Fabiola Montoya de Restrepo, ; Marcos Restrepo, ; Ángela Restrepo Moreno, . - 1983.
Obra : Journal of Medical and Veterinary Mycology
Idioma : Inglés (eng)
Resumen : The frequencies of blood groups, Rh and HLA antigens were studied in a series of patients with paracoccidioidomycosis as well as in control subjects. Statistical analysis of the results showed that only 2 antigens (HLA-A9 and HLA-B13) had a significantly increased frequency among patients with paracoccidioidomycosis compared with healthy controls. Among patients with paracoccidioidomycosis antigen HLA-A9 was significantly more prevalent in progressive pulmonary forms of the disease than in patients with extra pulmonary involvement. These observations suggest that HLA-A9 may influence susceptibility to the mycosis as well as its course. Mención de responsabilidad : Fabiola Montoya de Restrepo, Marcos Restrepo, Angela Restrepo Referencia : Sabouraudia. 1983 Mar;21(1):35-9. DOI (Digital Object Identifier) : 10.1080/00362178385380061 PMID : 6405491 En línea : https://academic.oup.com/mmy/article-abstract/21/1/35/1640462 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4326 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000827 AC-1983-003 Archivo digital Producción Científica Artículos científicos Disponible Survival of paracoccidioides brasiliensis yeast cells under microaerophilic conditions / Ángela Restrepo Moreno ; Beatriz Elena Jiménez ; Catalina de Bedout Gómez
Título : Survival of paracoccidioides brasiliensis yeast cells under microaerophilic conditions Tipo de documento : documento electrónico Autores : Ángela Restrepo Moreno, ; Beatriz Elena Jiménez, ; Catalina de Bedout Gómez, Fecha de publicación : 1981 Títulos uniformes : Journal of Medical and Veterinary Mycology Idioma : Inglés (eng) Resumen : The ability of P. brasiliensis yeast cells to withstand microaerophilic conditions was investigated in a liquid medium distributed in tall columns in screw-capped tubes. Young cells of three isolates were inoculated on top of the medium, and the tubes were incubated aerobically and anaerobically at 36°C for 28 days. The viability of cells that had sedimented to the bottoms of the tubes was studied by fluorescent microscopy and by their capacity to resume growth when transferred to fresh medium under continuous agitation. The proportion of viable cells in the sediments diminished with time of incubation. However, after 28 days, 27% of the cells were still viable and fully capable of active growth when placed under adequate aeration. On the other hand, drastic reduction of oxygen access elicited an accelerated death rate, with no survival after 7 days of incubation. Mención de responsabilidad : Angela Restrepo, Beatriz Elena Jiménez, Catalina de Bedout Referencia : Sabouraudia. 1981 Dec;19(4):301-5. DOI (Digital Object Identifier) : 10.1080/00362178185380481 PMID : 7034241 En línea : https://academic.oup.com/mmy/article-abstract/19/4/301/1697303 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4320 Survival of paracoccidioides brasiliensis yeast cells under microaerophilic conditions [documento electrónico] / Ángela Restrepo Moreno, ; Beatriz Elena Jiménez, ; Catalina de Bedout Gómez, . - 1981.
Obra : Journal of Medical and Veterinary Mycology
Idioma : Inglés (eng)
Resumen : The ability of P. brasiliensis yeast cells to withstand microaerophilic conditions was investigated in a liquid medium distributed in tall columns in screw-capped tubes. Young cells of three isolates were inoculated on top of the medium, and the tubes were incubated aerobically and anaerobically at 36°C for 28 days. The viability of cells that had sedimented to the bottoms of the tubes was studied by fluorescent microscopy and by their capacity to resume growth when transferred to fresh medium under continuous agitation. The proportion of viable cells in the sediments diminished with time of incubation. However, after 28 days, 27% of the cells were still viable and fully capable of active growth when placed under adequate aeration. On the other hand, drastic reduction of oxygen access elicited an accelerated death rate, with no survival after 7 days of incubation. Mención de responsabilidad : Angela Restrepo, Beatriz Elena Jiménez, Catalina de Bedout Referencia : Sabouraudia. 1981 Dec;19(4):301-5. DOI (Digital Object Identifier) : 10.1080/00362178185380481 PMID : 7034241 En línea : https://academic.oup.com/mmy/article-abstract/19/4/301/1697303 Enlace permanente : https://hospitalpablotobon.cloudbiteca.com/pmb/opac_css/index.php?lvl=notice_display&id=4320 Reserva
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Código de barras Número de Ubicación Tipo de medio Ubicación Sección Estado DD000821 AC-1981-001 Archivo digital Producción Científica Artículos científicos Disponible